Results 61 to 70 of about 387,146 (299)

Comparison of kinship‐identification methods for robust stock assessment using close‐kin mark–recapture data for Pacific bluefin tuna

Population Ecology, EarlyView.
In this study, we compared three methods for kinship identification using different algorithms in samples of wild Pacific bluefin tuna and generated genotyping data. The three methods resulted in different numbers of inferred kinship pairs for both generated and actual data. Particularly for the half‐sibling pairs, considerable number of false‐positive
Yohei Tsukahara, Reiichiro Nakamichi, Aiko Matsuura, Tetsuya Akita, Atushi Fujiwara, Nobuaki Suzuki   +5 more
wiley   +1 more source

Constraints on radiatively inefficient accretion history from Eddington ratio distribution of active galactic nuclei [PDF]

Mon.Not.Roy.Astron.Soc.377:425-429,2007, 2005
The transition of a standard thin disk to a radiatively inefficient accretion flow (RIAF) is expected to occur, when the accretion rate is close to the critical rate. The radiative efficiencies of accretion flows accreting at rates lower than the critical accretion rate become significantly lower than that of standard thin disks.
arxiv   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Accretion rates and accretion efficiency in AGNs [PDF]

, 2003
We used the standard geometrical thin accretion theory to obtain the accretion rates in Seyfert 1 galaxies and quasars. Combining accretion rates with the bolometric luminosity, we obtained the accretion efficiency. We found most of Seyfert 1 galaxies and radio quiet quasars have lower accretion efficiencies while most of the radio loud quasars possess
arxiv   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

On the efficiency of jet production in FR II radio galaxies and quasars [PDF]

, 2016
Jet powers in many radio galaxies with extended radio structures appear to exceed their associated accretion luminosities. In systems with very low accretion rates, this is likely due to the very low accretion luminosities resulting from radiatively inefficient accretion flows.
arxiv   +1 more source

Cold, clumpy accretion onto an active supermassive black hole [PDF]

Nature, 2016
The so-called accretion flow that powers the growth of supermassive black holes in galaxy centres is assumed to be dominated by a smooth, steady flow of very hot plasma, but now observations instead reveal a clumpy accretion of very cold molecular clouds
Grant R. Tremblay, Grant R. Tremblay, J. Oonk, J. Oonk, F. Combes, P. Salomé, C. O’Dea, C. O’Dea, S. Baum, S. Baum, G. Voit, M. Donahue, B. McNamara, T. A. Davis, T. A. Davis, Michael McDonald, A. Edge, T. Clarke, Roberto Galván-Madrid, Roberto Galván-Madrid, M. Bremer, L. O. V. Edwards, A. C. Fabian, S. Hamer, Yuan Li, A. Maury, H. Russell, A. Quillen, C. Urry, J. Sanders, M. Wise   +30 more
semanticscholar   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Global Evolution of an Accretion Disk with a Net Vertical Field: Coronal Accretion, Flux Transport, and Disk Winds [PDF]

, 2017
We report results from global ideal MHD simulations that study thin accretion disks (with thermal scale height H/R = 0.1 and 0.05) threaded by net vertical magnetic fields.
Zhaohuan Zhu, J. Stone
semanticscholar   +1 more source

Insights into the renal pathophysiology in Hermansky‐Pudlak syndrome‐1 from urinary extracellular vesicle proteomics and a new mouse model

FEBS Letters, EarlyView.
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard, Bernadette R. Gochuico, Hadass Pri Chen, Christopher K. E. Bleck, Patricia M. Zerfas, Wendy J. Introne, William A. Gahl, May C. V. Malicdan   +7 more
wiley   +1 more source