Results 101 to 110 of about 1,341,464 (302)

Effects of Hardening Model and Variation of Elastic Modulus on Springback Prediction in Roll Forming

open access: yesMetals, 2019
In this paper, the uniaxial loading−unloading−reloading (LUR) tensile test was conducted to determine the elastic modulus depending on the plastic pre-strain. To obtain the material parameters and parameter of Yoshida-Uemori’s kinematic
Jihad Naofal   +2 more
doaj   +1 more source

Bifurcation analysis based on a material model with stress-rate dependency and non-associated flow rule for fracture prediction in metal forming [PDF]

open access: yes, 2017
Recent increasing application of advanced high-strength metals causes grow-ing demand for accurate fracture prediction in metal forming simulation. However, since the construction of objective and reliable fracture prediction method is generally difficult,
Ito, Koichi   +4 more
core  

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Elliptical Galaxies with Emission Lines from the Sloan Digital Sky Survey

open access: yes, 2005
We present the results of 11 elliptical galaxies with strong nebular emission lines during our study of star formation history along the Hubble sequence. After removing the dilution from the underlying old stellar populations by use of stellar population
Barger A J   +34 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

A Microstructure-Integrated Ductile Fracture Criterion and FE-Based Framework for Predicting Warm Formability of AA7075 Sheets

open access: yesMetals
Variations in the warm formability of AA7075 sheets are primarily attributed to differences in precipitate morphology resulting from distinct thermal histories.
Wan-Ling Chen, Rong-Shean Lee
doaj   +1 more source

The Kinematics of Multiple-Peaked Lyα Emission in Star-Forming Galaxies at z ~ 2-3 [PDF]

open access: yes, 2012
We present new results on the Lyα emission-line kinematics of 18 z ~ 2-3 star-forming galaxies with multiple-peaked Lyα profiles. With our large spectroscopic database of UV-selected star-forming galaxies at these redshifts, we have determined that ~30 ...
Hainline, Kevin N.   +5 more
core  

Shear flow-interchange instability in nightside magnetotail causes auroral beads as a signature of substorm onset

open access: yes, 2019
A geometric wedge model of the near-earth nightside plasma sheet is used to derive a wave equation for low frequency shear flow-interchange waves which transmit $\vec{E} \times \vec{B}$ sheared zonal flows along magnetic flux tubes towards the ionosphere.
Derr, Jason   +2 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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