Results 101 to 110 of about 132,338 (329)

HYPERGLYCEMIA ON THE BACKGROUND OF TREATMENT OF COVID-19-ASSOCIATED PNEUMONIA USING GLUCOCORTICOIDS

open access: yesJuvenis Scientia, 2021
The pandemic of coronavirus pneumonia caused by SARS-CoV-2 virus and its multiple complications are a global issue of the day. Coronavirus infection is more severe in patients having chronic concomitant diseases.
A. V. Alimov   +6 more
doaj  

High-Purity Functional Corneal Endothelial Cells From Human Induced Pluripotent Stem Cells via a Novel Wash-Out Method. [PDF]

open access: yesMedComm (2020)
iPSC‐derived corneal endothelial cells purified via a novel wash‐out method show high functional fidelity, resemble primary CECs, and restore corneal clarity in vivo, offering a scalable alternative to donor transplantation. ABSTRACT Corneal endothelial failure can cause blindness, with transplantation as the only treatment.
Ye EA   +10 more
europepmc   +2 more sources

Therapeutic potential of the renin angiotensin system in ischaemic stroke [PDF]

open access: yes, 2016
The renin angiotensin system (RAS) consists of the systemic hormone system, critically involved in regulation and homeostasis of normal physiological functions [i.e.
Arroja, Mariana Moreira Coutinho   +2 more
core   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

open access: yesiNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu   +5 more
wiley   +1 more source

Study on the Clinical Significance of ACE2 and Its Age-Related Expression

open access: yesJournal of Inflammation Research, 2021
Jie Gu,1,* JiangWen Yin,1,* MengJie Zhang,1,* JinHui Li,1 YeMing Wu,2 Jun Chen,1 HongJun Miao1 1Department of Emergency/Critical care Medicine, Children’s Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, 210008, People’s ...
Gu J   +6 more
doaj  

Sitagliptin: a potential drug for the treatment of COVID-19?

open access: yesActa Pharmaceutica, 2021
Recently, an outbreak of a fatal coronavirus, SARS-CoV-2, has emerged from China and is rapidly spreading worldwide. Possible interaction of SARS-CoV-2 with DPP4 peptidase may partly contribute to the viral pathogenesis.
Bardaweel Sanaa K.   +2 more
doaj   +1 more source

Pathological Ace2-to-Ace enzyme switch in the stressed heart is transcriptionally controlled by the endothelial Brg1–FoxM1 complex [PDF]

open access: yes, 2016
Genes encoding angiotensin-converting enzymes (Ace and Ace2) are essential for heart function regulation. Cardiac stress enhances Ace, but suppresses Ace2, expression in the heart, leading to a net production of angiotensin II that promotes cardiac ...
Chang, Ching-Pin   +9 more
core   +1 more source

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

open access: yesInterdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi   +6 more
wiley   +1 more source

SARS-CoV-2 (COVID-19) Adhesion Site Protein Upregulation in Small Airways, Type 2 Pneumocytes, and Alveolar Macrophages of Smokers and COPD – Possible Implications for Interstitial Fibrosis

open access: yesInternational Journal of COPD, 2022
Samuel James Brake,1 Mathew Suji Eapen,1 Kielan Darcy McAlinden,1 James Markos,1,2 Greg Haug,1,2 Josie Larby,1,2 Collin Chia,1,2 Ashutosh Hardikar,1,3 Gurpreet Kaur Singhera,4,5 Tillie L Hackett,4,5 Wenying Lu,1 Sukhwinder Singh Sohal1 1Respiratory ...
Brake SJ   +11 more
doaj  

The Use of ACE inhibitor/ARB in SARS-CoV-2 Patients: A Comprehensive Narrative Review

open access: yesAsian Journal of Medical Sciences, 2020
The three most common comorbidities that are associated with increased mortality in COVID-19 patients are Hypertension, Diabetes, and Cardiovascular disease, Angiotensin-converting enzyme (ACE) inhibitors and Angiotensin II receptor blockers (ARB) are ...
Timotius Ivan Hariyanto   +5 more
doaj   +1 more source

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