Results 251 to 260 of about 149,286 (348)

The Regulation Role of the Gut-Islets Axis in Diabetes

Diabetes, Metabolic Syndrome and Obesity
Songtao Yang,1 Jie Cao,1 Chuan Sun,2 Li Yuan1 1Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 2Department of Emergency Medical, Wuhan ASIA ...
Yang S, Cao J, Sun C, Yuan L
doaj  

Electrochemical Detection of SARS‐CoV‐2 in Saliva Using ZnO Nanorods Functionalized with Gold‐Conjugated Antireceptor‐Binding Domain Antibodies

ChemNanoMat, Volume 12, Issue 1, January 2026.
An electrochemical immunosensor based on ZnO nanorods functionalized with gold nanoparticle‐conjugated anti‐receptor‐binding domain antibodies enables rapid, noninvasive, and selective detection of SARS‐CoV‐2 in saliva, providing a promising platform for point‐of‐care diagnostic applications.
Fabíola Lelis de Castro, Ana Cristina Honorato Castro‐Kochi, Marcos Roberto de Araújo Silva, Priscila Sabbag Ferreira, Sydney Ferreira Santos, Lídia Maria de Andrade, Mariano Venanzi, Francesca Cavalieri, Mariângela de Oliveira Silva, Isabela Pazotti Daher, Catarina Harumi Oda Ibrahim, Vivian Leite de Oliveira, Jorge Kalil, Tamires Lopes Silva, Silvia Beatriz Boscardin, Wendel Andrade Alves   +15 more
wiley   +1 more source

Fullerenol C60(OH)40 Nanoparticles and Ectoine Protect Human Nasal Epithelial Cells Against the Cytokine Storm After Addition of the Full-Length Spike Protein from SARS-CoV-2

International Journal of Nanomedicine
Malwina Sosnowska,1 Mateusz Wierzbicki,1 Barbara Nasiłowska,2 Totka Nikolaeva Bakalova,3 Klara Piotrowska,4 Barbara Strojny-Cieślak,1 Ewa Sawosz,1 Marta Kutwin1 1Department of Nanobiotechnology, Institute of Biology, Warsaw University of ...
Sosnowska M, Wierzbicki M, Nasiłowska B, Bakalova TN, Piotrowska K, Strojny-Cieślak B, Sawosz E, Kutwin M   +7 more
doaj  

Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction

, 2021
Amit Mahindra, Gonzalo S. Tejeda, Mario Rossi, Omar Janha, Imogen Herbert, Caroline Morris, Danielle C. Morgan, Wendy Beattie, Augusto C. Montezano, Brian Hudson, Andrew B. Tobin, David Bhella, Rhian M. Touyz, Andrew G. Jamieson, George S. Baillie, Connor M. Blair   +15 more
openalex   +1 more source

Prolonged persistence of tissue‐resident memory cells in the upper airway following SARS‐CoV‐2 infection and vaccination

Clinical &Translational Immunology, Volume 15, Issue 1, 2026.
In this study, we found that both SARS‐CoV‐2 infection and vaccination elicit long‐lived tissue‐resident immune responses in the nasopharynx (NP), marked by persistent TRM and BRM cells. Our experiment data determine that subjects with breakthrough infections exhibit significantly enhanced frequencies and polyfunctionality of CD4+ TRM cells, along with
Hyunkyung Cha, Jina Won, Soo Min Kim, Suhyun Lim, Sujin Kim, Siyeon Jin, Sung Dong Cho, Hyun Jik Kim   +7 more
wiley   +1 more source

Tolerability, Safety, and Pharmacokinetics of Ivermectin After Nasal Application in Healthy Adult Subjects

The Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.
Abstract Nasal epithelium is the site of infection for SARS‐CoV2 viruses, with interactions of the viral spike protein with the ACE2 receptor of the host cell. Molecular docking studies have shown that ivermectin shields the spike protein and thereby prevents binding to ACE2.
Stefan Wissel, Philipp Wissel, Matthias Rischer, Felix Häberlein, Hilde Riethmüller‐Winzen, Hanns Häberlein   +5 more
wiley   +1 more source

Clinical Significance and Potential Molecular Mechanisms of Angiotensin-Converting Enzyme 2 in Colorectal Cancer. [PDF]

World J Oncol
Zeng DT, Yang L, Wen JY, Wu KJ, Chen GQ, Li ZY, Ling JW, Huang BB, Xie YY, Dong YY, Fang YY, Wei DM, Chen G, Shi L, Huang WJ.   +14 more
europepmc   +1 more source

A peptide array pipeline for the development of Spike-ACE2 interaction inhibitors

, 2022
Anand Chopra, Ali H. Shukri, Hemanta Adhikary, Valentina Lukinović, Matthew Hoekstra, Michael Cowpland, Kyle K. Biggar   +6 more
openalex   +2 more sources

Structural Adaptability of IgA and IgM Supports Broad SARS‐CoV‐2 Variant Neutralization

Journal of Medical Virology, Volume 98, Issue 1, January 2026.
ABSTRACT Neutralizing emerging SARS‐CoV‐2 variants requires antibodies effective not only against epitope mutations but also under variable antigenic presentations. We assessed the neutralization capacity of the same anti‐RBD monoclonal antibody (8A5) expressed as IgG, IgA, or IgM against 18 variants, identifying three neutralization classes: variants ...
Yalcin Pisil, Hisatoshi Shida, Sandra Morales Ruiz, Kyunghak Cho, Metehan Gungor, Zafer Yazici, Tomoyuki Miura   +6 more
wiley   +1 more source

Dual role of ACE2 in regulating inflammation triggered by Omicron S1 and other SARS-CoV-2 Spike variants. [PDF]

Front Immunol
Pedoto A, Lozano-Gil JM, Ocaña-Esparza M, Conesa-Hernández AM, Candel S, Cayuela ML, Mulero V, Tyrkalska SD.   +7 more
europepmc   +1 more source