Results 51 to 60 of about 149,286 (348)

Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19

Critical Care, 2020
An outbreak of pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that started in Wuhan, China, at the end of 2019 has become a global pandemic.
W. Ni, Xiuwen Yang, Deqing Yang, J. Bao, Ran Li, Yongjiu Xiao, C. Hou, Haibin Wang, Jie Liu, Dong-hong Yang, Yu Xu, Zhaolong Cao, Zhancheng Gao   +12 more
semanticscholar   +1 more source

Triglyceride regulate ACE2 level through MTHFD1 [PDF]

Journal of Biosciences, 2021
Obesity has been followed with interest as a risk factor for COVID-19, with triglycerides as one of four common criteria used to define obesity, which have been used to study the mechanism of obesity. In this study, we showed that angiotensin-converting enzyme-2 (ACE2) is widely expressed in the mouse body, including the kidney, spleen, brain, heart ...
Xiaohua Ma, Xiaojing Li, Bo Wan, Zhigang Miao   +3 more
openaire   +2 more sources

The Use of ACE inhibitor/ARB in SARS-CoV-2 Patients: A Comprehensive Narrative Review

Asian Journal of Medical Sciences, 2020
The three most common comorbidities that are associated with increased mortality in COVID-19 patients are Hypertension, Diabetes, and Cardiovascular disease, Angiotensin-converting enzyme (ACE) inhibitors and Angiotensin II receptor blockers (ARB) are ...
Timotius Ivan Hariyanto , Karunia Valeriani Japar , Vika Damay , Felix Kwenandar , Novia Lauren Sieto , Andree Kurniawan   +5 more
doaj   +1 more source

Lactate signalling regulates fungal β-glucan masking and immune evasion [PDF]

, 2016
AJPB: This work was supported by the European Research Council (STRIFE, ERC- 2009-AdG-249793), The UK Medical Research Council (MR/M026663/1), the UK Biotechnology and Biological Research Council (BB/K017365/1), the Wellcome Trust (080088; 097377).
A Hopke, B Ferwerda, BN Gantner, C Kuei, CA Johnston, CA Munro, CA Rappleye, CJ Barelle, CJ Heilmann, DH Owen, DO Inglis, E Leberer, FN Gravelat, G Bindea, GD Brown, GJ Sosinska, HJ Flint, I Jacobs, ID Iliev, IV Ene, IV Ene, IV Ene, IV Ene, JE Nett, JM Bain, K Lemaire, LE Lewis, LM Graham, M Galán-Díez, M Karababa, M Santos, MG Netea, MG Netea, MJ Marakalala, MM Maidan, MT Kelly, N Vieira, NAR Gow, P Shannon, PR Desai, RA Hall, RT Wheeler, RT Wheeler, RT Wheeler, S Lev, S Shahana, SdJ Carrion, SE Hardison, SM Noble, TR O'Meara, YL Chen   +50 more
core   +1 more source

ACE2 ACTIVATION PROMOTES ANTITHROMBOTIC ACTIVITY

The FASEB Journal, 2009
Hyperactivity of the axis ACE/AngII/AT1R of the renin‐angiotensin system is associated with occurrence of acute thrombotic event. Recently a novel concept of a counterrugulatory axis, ACE2/Ang‐(1‐7)/Mas, has emerged. We hypothesized that ACE2 would be protective against thrombosis.
Rodrigo A, Fraga-Silva, Brian S, Sorg, Mamta, Wankhede, Casey, Dedeugd, Joo Y, Jun, Matthew B, Baker, Yan, Li, Ronald K, Castellano, Michael J, Katovich, Mohan K, Raizada, Anderson J, Ferreira   +10 more
openaire   +2 more sources

Evaluation of the effect of angiotensin converting enzyme2 in corona pandemic affect female infertility: A review article

Fiyz̤, 2021
Background: Recently in 2019, a novel virus from coronavirus family (Sars-CoV-2) was introduced in China. ACE2 is a zinc metalloprotease played role in the angiotensin system.
Mosleh HR, Mehdizadeh M, Moradi F, Moeinzadeh A, Shabani R   +4 more
doaj  

Immunocytochemical Assessment of ACE2 and TMPRSS2 in Nasopharyngeal Swabs from SARS-CoV-2 Patients

Frontiers in Bioscience-Landmark, 2022
Background: SARS-CoV-2 is a positive-sense single-stranded RNA virus. It is enveloped by four structural proteins. The entry of the virus into the host cells is mediated by spike protein binding to the angiotensin converting enzyme 2 (ACE2) and ...
Karla Beatríz Peña, Josep Gumà, Carmen Guilarte, Lola Delamo, Marc Grifol, Berta Pique, Anna Hernandez, Helena Casteñé, Francesc Riu, David Parada   +9 more
doaj   +1 more source

Distinct regions of the Swi5 and Ace2 transcription factors are required for specific gene activation [PDF]

, 1999
Swi5 and Ace2 are cell cycle-regulated transcription factors that activate expression of early G1-specific genes in Saccharomyces cerevisiae. Swi5 and Ace2 have zinc finger DNA-binding domains that are highly conserved, and the two proteins bind to the ...
McBride, Helen J., Stillman, David J., Yu, Yaxin   +2 more
core   +2 more sources

Angiotensin-converting enzyme 2 activation suppresses pulmonary vascular remodeling by inducing apoptosis through the Hippo signaling pathway in rats with pulmonary arterial hypertension

Clinical and Experimental Hypertension, 2019
Objective: To investigate the effects of angiotensin-converting enzyme 2 (ACE2) activation on pulmonary arterial cell apoptosis during pulmonary vascular remodeling associated with pulmonary arterial hypertension (PAH) and to elucidate potential ...
Daole Yan, Gang Li, Yaozhong Zhang, Yinglong Liu   +3 more
doaj   +1 more source

ACE2 in tumor cells and tumor vasculature: Negligible intercellular transfer from cancer cells into endothelial cells

Visualized Cancer Medicine, 2021
Cancer patients are more susceptible to severe coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Angiotensin-converting enzyme 2 (ACE2) is the functional host receptor for SARS-
Liu Zhi-Jie, Mei Yan, Lu Jiang-Li, Lu Jia-Bin, Cao Yun, Cai Mu-Yan, Zheng Li-Sheng, Wang Ming-Dian, Peng Li-Xia, Li Yang, Huang Bi-Jun, Yun Jin-Ping, Qian Chao-Nan   +12 more
doaj   +1 more source