Results 81 to 90 of about 149,286 (348)

A Case of Novel Coronavirus Disease 19 in a Chronic Hemodialysis Patient Presenting with Gastroenteritis and Developing Severe Pulmonary Disease. [PDF]

, 2020
Novel coronavirus disease 2019 (COVID-19) is a highly infectious, rapidly spreading viral disease with an alarming case fatality rate up to 5%.
Amin, Alpesh N, Chang, Yongen, Cheng, Timmy T, Choi, Grace, Ferrey, Antoney J, Gohil, Shruti, Hanna, Ramy M, Hsieh, Lanny, Huang, Susan S, Ivaturi, Kaushik, Kalantar-Zadeh, Kamyar, Lau, Wei Ling, Lee, Richard A, Nguyen, Lawrence, Park, Elisa, Reddy, Uttam, Rhee, Connie M, Tantisattamo, Ekamol, Tonthat, Sam, Wang, Brian   +19 more
core   +1 more source

Obesity and COVID-19: A Perspective from the European Association for the Study of Obesity on Immunological Perturbations, Therapeutic Challenges, and Opportunities in Obesity

Obesity Facts, 2020
Accumulating evidence suggests that obesity is a major risk factor for the initiation, progression, and outcomes of coronavirus disease 2019 (COVID-19).
Gijs H. Goossens, Dror Dicker, Nathalie J. Farpour-Lambert, Gema Frühbeck, Dana Mullerova, Euan Woodward, Jens-Christian Holm   +6 more
doaj   +1 more source

Combining VEGF receptor inhibitors and angiotensin-(1–7) to target renal cell carcinoma

Molecular & Cellular Oncology, 2021
Resistance to tyrosine kinase inhibitors of the vascular endothelial growth factor receptor inevitably develops in most patients with metastatic kidney cancer.
Thomas Walther, Prateek Khanna, Rupal S. Bhatt   +2 more
doaj   +1 more source

ACE2 [PDF]

Journal of the American Society of Nephrology, 2006
Abundant, well-accepted evidence demonstrates a complete tissue renin-angiotensin system (RAS) within the kidney that plays many roles in the control of the intrarenal vasculature, as well in the control of glomerular and tubular processes ([1][1]).
openaire   +2 more sources

Pharmacophore mapping of Angiotensin Converting Enzymes (ACEs): Insight to Binding Site of ACE1 and ACE2

Biology, Medicine & Natural Product Chemistry
Angiotensin Converting Enzymes (ACEs) are carboxypeptidase enzymes involved in the renin-angiotensin system (RAS), which catalyze angiotensin I by cleavage of the peptide bond. ACE1 has been known as a target for antihypertensive drugs.
Navista Sri Octa Ujiantari, Cintya Nurul Apsari   +1 more
doaj   +1 more source

Regulation of Ace2-dependent genes requires components of the PBF complex in schizosaccharomyces pombe [PDF]

, 2015
The division cycle of unicellular yeasts is completed with the activation of a cell separation program that results in the dissolution of the septum assembled during cytokinesis between the 2 daughter cells, allowing them to become independent entities ...
Alonso-Nuñez, María Luisa, del Rey, Francisco, McInerny, Christopher J., Suárez, M Belén, Vázquez de Aldana, Carlos R   +4 more
core   +1 more source

The novel coronavirus 2019 (2019-nCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells

bioRxiv, 2020
The emergence of a novel, highly pathogenic coronavirus, 2019-nCoV, in China, and its rapid national and international spread pose a global health emergency.
M. Hoffmann, Hannah Kleine-Weber, Nadine Krüger, Marcel Müller, C. Drosten, S. Pöhlmann   +5 more
semanticscholar   +1 more source

Molecular Docking and Fragment-Based QSAR Modeling for In Silico Screening of Approved Drugs and Candidate Compounds Against COVID-19 [PDF]

Avicenna Journal of Medical Biochemistry, 2020
Background: Coronavirus disease 2019 (COVID-19) as a serious global health crisis leads to high mortality and morbidity. However, currently, there are no effective vaccines and treatments for COVID-19.
Saeid Afshar, Asrin Bahmani, Massoud Saidijam   +2 more
doaj   +1 more source

A novel mechanism of action for angiotensin-(1-7) via the angiotensin type 1 receptor [PDF]

, 2016
No abstract ...
Nicklin, Stuart A.
core   +1 more source

Specific ACE2 Expression in Cholangiocytes May Cause Liver Damage After 2019-nCoV Infection

bioRxiv, 2020
A newly identified coronavirus, 2019-nCoV, has been posing significant threats to public health since December 2019. ACE2, the host cell receptor for severe acute respiratory syndrome coronavirus (SARS), has recently been demonstrated in mediating 2019 ...
Xiaoqiang Chai, Longfei Hu, Yan Zhang, Weiyu Han, Zhou Lu, A. Ke, Jian Zhou, G. Shi, Nan Fang, Jia Fan, Jia-Bing Cai, Jue Fan, F. Lan   +12 more
semanticscholar   +1 more source