Results 121 to 130 of about 620,051 (294)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
ANGIOTENSIN II RECEPTOR ANTAGONISTS AND PROTEINURIA
Zdravniški Vestnik, 2002 Background. In numerous clinical studies that tried to identify risk factors for progressive renal function loss, the severity of proteinuria correlated with the rate of renal function loss.
Tanja Kök, Radovan Hojs
doaj
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
World NutritionOne risk factor for high blood pressure is obesity. An enzyme called the angiotensin-converting enzyme (ACE) is responsible for vasoconstriction. It is possible that ACE gene insertion or deletion polymorphisms are linked to hypertension.
MUHAMMAD ALI GAMBO +2 more
doaj +1 more source
A critical appraisal of the intrinsic pancreatic angiotensin-generating system [PDF]
, 2001 The pancreas is a relative newcomer to the stable of tissues with an intrinsic angiotensin-generating system. The involvement of this system in pancreatic activity will be dependent on the angiotensin-generating paths present in the pancreas and their ...
Sernia, Conrad
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Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Benefits of perindopril all along the cardiovascular continuum: the level of evidence. [PDF]
, 2011 Clinical efficacy of perindopril has been proved by using extensive clinical randomized studies in patients with hypertension, diabetes, cerebrovascular disease, stable coronary heart disease (CHD) and heart failure.
Aleksandar Knežević
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
استخراج و بهينهسازی تخليص چند مرحلهای آنزيم تبديل کننده آنژيوتانسين I(ACE) از ريه خرگوش [PDF]
, 2005 آنزيم تبديل کننده آنژيوتانسين I(ACE) يک پپتيديل دی پپتيد هيدرولاز است که 2 اسيد آمينه انتهای کربوکسيلی(His-Leu) را از آنژيوتانسين I که يک دکاپپتيد است جدا کرده و آنژيوتانسين II(يک اکتاپپتيد) را توليد مینمايد.
شعبانی, محمد +4 more
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