Results 261 to 270 of about 141,407 (287)
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Vascular Effects of ACE Inhibition by Perindopril
Drugs, 1990Hypertension and ageing are associated with decreased arterial compliance, increased thickening of the arterial wall, hypertrophy of arterial smooth muscle cells and an increase in the collagen content of the arterial wall. Increased blood pressure has been implicated as a causative factor in such adaptive vascular alterations, however, other factors ...
J B, Michel, B I, Levy
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ACE Inhibition in Cardiovascular Disease
New England Journal of Medicine, 2000An important article in this issue of the Journal describes the results of the Heart Outcomes Prevention Evaluation (HOPE) study, which are likely to have important implications for the treatment o...
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Journal of Cardiovascular Pharmacology, 1990
Results of uncontrolled studies suggest that the duration of action of an ACE inhibitor may be an important determinant of renal impairment when using these agents to treat patients with heart failure. To determine whether there is experimental evidence for this hypothesis, we compared the effects of intermittent (captopril, 25 mg i.v.
M A, Fitzpatrick +6 more
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Results of uncontrolled studies suggest that the duration of action of an ACE inhibitor may be an important determinant of renal impairment when using these agents to treat patients with heart failure. To determine whether there is experimental evidence for this hypothesis, we compared the effects of intermittent (captopril, 25 mg i.v.
M A, Fitzpatrick +6 more
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Triple ACE-ECE-NEP Inhibition in Heart Failure: A Comparison With ACE and Dual ECE-NEP Inhibition
Journal of Cardiovascular Pharmacology, 2005Abstract: Mortality remains high in chronic heart failure (CHF) because under ACE inhibitor treatment other neurohumoral systems remain/become (de)activated, such as the endothelin and atrial natriuretic peptide pathways.
Virginie, Mellin +6 more
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ACE inhibition in the tissues.
Clinical physiology and biochemistry, 1993The discovery of the components of the renin angiotensin system (RAS) in various tissues gave rise to the idea that functional "tissue" renin-angiotensin systems exist that are more or less independent of the hormonal RAS. Further support to this notion came from the recent demonstration of the mRNA for the protein components of the RAS in a number of ...
T, Unger, P, Gohlke
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Relationships Among Diabetes, Microalbuminuria, and ACE Inhibition
Journal of Cardiovascular Pharmacology, 1998Increasing worldwide rates of diabetes mellitus, combined with the significant micro- and macrovascular complications that accompany the disease, point to a heightened need to develop simple, rational strategies to protect against end-organ damage, particularly diabetic nephropathy.
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ACE Inhibition in Acute Myocardial Infarction
New England Journal of Medicine, 1995Any new therapeutic advance requires clear proof of effectiveness from well-designed and well-conducted clinical trials that establish both the range of anticipated benefits and the potential adver...
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ACE-INHIBITED RENAL SCINTIGRAPHY
Investigative Radiology, 1991J. Rohltinq, K. A. Morton, F. L Dalz
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