Results 91 to 100 of about 3,911 (190)

Synthesis of 4-styrylquinazolines enabled by a hypervalent iodine-promoted oxidative amination cascade

Tetrahedron Chem
Efficient synthetic routes to pharmaceutically important 4-styrylquinazolines scaffolds are of considerable interest. Herein, we report a concise synthesis of 4-styrylquinazoline derivatives via a hypervalent iodine-promoted oxidative amination cascade ...
Lipeng Long, Ziyi Yu, Ziwen Huang, Min Ye, Wenjun Luo, Xunjin Jiang, Zhengwang Chen, Zhong-Xia Wang   +7 more
doaj   +1 more source

Differential Analysis of IAA Anabolism Pathway Based on Bacillus cereus, Bacillus subtilis and Bacillus safensis Genome

Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.
Three Bacillus species isolated from Platycladus orientalis rhizosphere in Taihang Mountains: Bacillus cereus has 3 IAA synthesis pathways (TAM, IAM, IPyA); Bacillus subtilis has IAM/IPyA; and Bacillus safensis only has IPyA (via whole‐genome sequencing).
Dongyue Hou, Xuejie Zhai, Kezhong Zhang, Jinteng Cui   +3 more
wiley   +1 more source

Assessment of amination reactions via nucleophilic aromatic substitution using conventional and eco-friendly energies

Green Chemistry Letters and Reviews, 2018
The efficiency of conventional heating energy source compared with Infrared (IR), Ultrasound (US), Microwave and the simultaneous combination US–IR eco-friendly approaches for preparation of new N-(5-R1 -amino-2-nitrophenyl)acetamides and 5-R1-amino-2 ...
Ricardo A. Luna-Mora, Ángeles Torres-Reyes, Oscar A. González-Cruz, Fernando Ortega-Jiménez, Hulme Ríos-Guerra, Jessica V. González-Carrillo, Francisco Barrera-Téllez, Javier Perez-Flores, José G. Penieres-Carrillo   +8 more
doaj   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, Volume 183, Issue 7, Page 1313-1340, April 2026.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

Polylimonene Improves the In Vivo Wound Healing Performance of Sodium Alginate‐Based Hydrogels

Journal of Applied Polymer Science, Volume 143, Issue 12, March 20, 2026.
An oligomer derived from orange peel essential oil incorporated into an alginate hydrogel was shown to be biocompatible and to exhibit a high capacity for in vivo incisional wound healing, as confirmed by experimental assays and mathematical models fitted to the data describing wound area reduction as a function of the dressing‐tissue contact time ...
Roniérik Pioli Vieira, Guilherme Frey Schutz, Oana‐Maria Chirliu, Aurelian‐Sorin Pasca, Lenuta Profire, Sandra Van Vlierberghe   +5 more
wiley   +1 more source

Quinic Acid and Synthetic Derivatives in Medicinal Chemistry

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel, Manuel J. Verganista, Nuno R. Candeias   +2 more
wiley   +1 more source

Ximenia americana L. From Popular Use to Anti‐Inflammatory Activities: A Comprehensive Review

Food Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT Ximenia americana (L.), known as “yellow plum,” “sea lemon,” or “Brazilian plum,” is a tropical/subtropical plant widely used in traditional medicine. Its roots, leaves, flowers, stem, and fruits are traditionally employed to treat various inflammatory disorders.
Bruno Anderson F. Silva, Maria Gabriely de Lima Silva, Eduardo S. Silva, Lucas Yure S. Silva, Renata Torres Pessoa, Silvio C. Alves‐Júnior, Jullyana S. S. Quintans, Laurent Picot, Irwin Rose A. Menezes, Lucindo J. Quintans‐Júnior   +9 more
wiley   +1 more source

Upcycling Agricultural By‐Product: Therapeutic Potential of Oriental Melon Stem (Cucumis melo var. makuwa) in Treating Obesity and Fatty Liver via Enhanced Thermogenesis

Food Frontiers, Volume 7, Issue 2, March 2026.
This study proposes the upcycling of oriental melon (Cucumis melo var. makuwa) stems, typically discarded as agricultural waste, into a bioactive extract with functional potential. CMSE ameliorates high‐fat‐diet‐induced obesity and fatty liver, contributing to the restoration of metabolic health by enhancing the expression of thermogenesis‐related ...
Myeong‐Jin Kim, Ji Yun Van, Su‐Yeon Park, Ji Young Hwang, Yerin Seong, Yeo Jin Park, Seokmin Lee, Bo‐mi Ryu, Joo Yun Jun, Won‐Kyo Jung, Bonggi Lee   +10 more
wiley   +1 more source

SYNTHESIS OF NEW N-PHENYL-N-(1-PHENYLHEX-5-EN-1-YL)ACETAMIDES AND THEIR 1H-NMR CONFORMATIONAL STUDY

Revista Colombiana de Química, 2014
The synthesis and characterization of different N-phenyl-N-(1-phenylhex-5-en-1-yl)acetamides is presented. Two conformational isomers were observed for one of the compounds in their1H/13C-NMR spectra.
Mauricio Acelas, Elizabeth Gil, Markus Doerr, Martha Daza, Juan Manuel Urbina   +4 more
doaj  

Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors

Medicinal Research Reviews, Volume 46, Issue 2, Page 445-474, March 2026.
ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara, Gómez‐Santacana Xavier, Llebaria Amadeu, Rovira Xavier   +3 more
wiley   +1 more source