Results 101 to 110 of about 21,852 (266)
Thermische Umlagerung von Benzyl-1-alkinyl-äthern in Gegenwart von Aminen
CHIMIA, 1972 The benzyl-l-alkynyl ethers 1a and 1b in the presence of ammonia or diethylamine at 50 to 80° are transformed into the corresponding o-tolyl-acetamides 4 to 6 (scheme 1). This observation gives good evidence that benzyl-1-alkynyl ethers 1 rearrange by a
A. Wunderli +3 more
doaj +1 more source
B(OCH2CF3)3-mediated direct amidation of pharmaceutically relevant building blocks in cyclopentyl methyl ether [PDF]
, 2015 The use of B(OCH2CF3)3 for mediating direct amidation reactions of a wide range of pharmaceutically relevant carboxylic acids and amines is described, including numerous heterocycle-containing examples.
Badland, M +4 more
core +1 more source
Annalen der Pharmacie, 2018 The intramolecular carbene C–H insertion of α-diazo-α(methoxycarbonyl)acetamides leading to β-lactams is effectively catalyzed by palladium complexes. It is found that whereas Pd(0)catalysts typically produce mixtures of β-lactams together with Buchner ...
D. Solé +3 more
semanticscholar +1 more source
Indole‐Based π‐Extended Monophosphine Ligands for Enhanced Palladium‐Catalyzed Sonogashira Coupling
Journal of Heterocyclic Chemistry, EarlyView.A general palladium‐catalyzed Sonogashira cross‐coupling of (hetero)aryl chlorides with aliphatic, (hetero)aryl alkynes is described using Pd(dba)₂/PCy2‐Napdole‐phos catalyst system. The reaction protocol exhibits broad substrate scope and the catalyst loading can be down to 0.2 mol% Pd.
Yu Kiu Lau +9 more
wiley +1 more source
Brazilian Journal of Pharmaceutical SciencesThe aim of the present research work was to investigate the enzyme inhibitory potential of some new sulfonamides having benzodioxane and acetamide moieties.
Muhammad Athar Abbasi +7 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2019 The condensation of primary amines with N-(1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-2-oxo-2-arylethyl)acetamides was explored. Thus, a previously unknown recyclization of the starting material was observed in acidic ethanol in the presence of an amine,
Valeriya G. Melekhina +9 more
doaj +1 more source
Cobalt-catalysed site-selective intra- and intermolecular dehydrogenative amination of unactivated sp3 carbons [PDF]
, 2015 Cobalt-catalysed sp2 C–H bond functionalization has attracted considerable attention in recent years because of the low cost of cobalt complexes and interesting modes of action in the process. In comparison, much less efforts have been devoted to the sp3
Ge, Haibo +5 more
core +1 more source
The continuing significance of chiral agrochemicals
Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley +1 more source
The Chemical Record, EarlyView.This review highlights the characteristic odor markers of illicit drugs, emphasizing volatile markers from both natural and synthetic sources, and explores the shift from canine‐based detection to emerging noncontact sensing technologies. Illicit drug use remains a global concern, requiring effective detection methods to counter evolving concealment ...
Minwoo Kim +4 more
wiley +1 more source
New methods for preparing N,N-dialkyltrifluoroacetamides [PDF]
The customary preparative methods for N,N-dialkyltrifluoroacetamides involve the acylation of an amine by trifluoroacetic acid or its derivatives.
Hsu, L.
core +1 more source