Results 1 to 10 of about 136,607 (334)
Use of Arctium lappa Extract Against Acetaminophen-Induced Hepatotoxicity in Rats [PDF]
Current Therapeutic Research, 2015 Background: Severe destructive hepatic injuries can be induced by acetaminophen overdose and may lead to acute hepatic failure. Objective: To investigate the ameliorative effects of Arctium lappa root extract on acetaminophen-induced hepatotoxicity ...
Attalla Farag El-Kott, PhD +1 more
doaj +7 more sources
J Educ Teach Emerg MedThis is a practice structured interview case which is appropriate for emergency medicine residents at all levels of training.Acetaminophen (APAP) is an over-the-counter medication commonly used by adult and pediatric populations. While acetaminophen has demonstrated to be reasonably safe and well-tolerated at therapeutic doses, it can cause severe ...
Whittaker R, Cheema N.
europepmc +4 more sources
Annals of Cardiac Anaesthesia, 2021 Context: Postoperative hyperthermia, which may lead to cognitive decline, is a common complication of cardiovascular surgery with cardiopulmonary bypass (CPB).
Shohei Kaneko +5 more
doaj +1 more source
Acetaminophen-induced hypotension in sepsis
Journal of Pharmaceutical Health Care and Sciences, 2022 Background Acetaminophen-induced hypotension has been reported in critically ill patients; however, it remains unclear whether mannitol, present as a stabilizing compound in acetaminophen formulations, affects hemodynamic changes.
Shunsuke Inage +8 more
doaj +1 more source
Toxicology Communications, 2022 Acetaminophen overdose is a leading cause of liver failure in the United States. Macrophage migration inhibitory factor (MIF) is a cytokine that is released early and promotes acetaminophen toxicity in preclinical models.
Joshua Bloom +3 more
doaj +1 more source
Delayed Acetaminophen Absorption Resulting in Acute Liver Failure
Case Reports in Critical Care, 2022 Introduction. Acetaminophen is a common medication involved in deliberate and accidental self-poisoning. The acetaminophen treatment nomogram is used to guide acetylcysteine treatment.
Huiling Tan +4 more
doaj +1 more source
Archives of Pharmacy Practice, 2017 Background: Acetaminophen poisoning is becoming an increasingly common social problem in Malaysia. An understanding of consumers' usage pattern of acetaminophen is essential in addressing the issue of accidental acetaminophen poisoning.
Chee Ping Chong +2 more
doaj +1 more source
PLoS ONE, 2015 Metabolomics approaches have enabled the study of new mechanisms of liver injury in experimental models of drug toxicity. Disruption of bile acid homeostasis is a known mechanism of drug induced liver injury.
Laura James +8 more
doaj +1 more source
Bananas decrease acetaminophen potency in in vitro assays. [PDF]
PLoS ONE, 2018 Edible portions of bananas contain high levels of polyphenol oxidase, which catalyzes reactions in the melanin formation pathway. Tyrosine, a physiological substrate of polyphenol oxidase, has an analogous structure to acetaminophen.
Yoshihiro Uesawa, Naotaka Tsuji
doaj +1 more source
Traditional and Integrative Medicine, 2023 In Traditional Persian Medicine (TPM) saffron is used as an accompaniment agent “Mobadreq” in poly herbal formulations. According to TPM texts, “Mobadreq” is a substance (or drug) which facilitates access of drugs or food to the whole body or specific ...
Seyede Nargess Sadati Lamardi +5 more
doaj +1 more source