Results 1 to 10 of about 113,832 (239)

Protective role of coenzyme Q10 against renal and hepatic toxicity induced by acetaminophen overdose in albino rats. [PDF]

Open Vet J
Background: Acetaminophen has an antipyretic activity by inhibiting prostaglandin synthesis found in the brain, and this action is responsible for its analgesic effect, but overdose can cause hepatic and renal toxicity.
Naser IH, Al-Kareem ZA, Ubaid MM, Kadhim SH.   +3 more
europepmc   +2 more sources

Perioperative anaphylaxis attributed to acetaminophen following intravenous acetaminophen administration: a case report. [PDF]

JA Clin Rep
Background Anaphylaxis caused by intravenous acetaminophen is extremely rare, but a few case reports have identified mannitol, an excipient, as the causative component.
Amano Y, Taki Y, Konishi Y, Fujii T, Tamura T.   +4 more
europepmc   +2 more sources

Effect of perioperative acetaminophen on body temperature after cardiovascular surgery with cardiopulmonary bypass: A single-center retrospective study

Annals of Cardiac Anaesthesia, 2021
Context: Postoperative hyperthermia, which may lead to cognitive decline, is a common complication of cardiovascular surgery with cardiopulmonary bypass (CPB).
Shohei Kaneko, Taiga Ichinomiya, Shuntaro Sato, Motohiro Sekino, Hiroaki Murata, Tetsuya Hara   +5 more
doaj   +1 more source

Acute effects of acetaminophen on the developmental, swimming performance and cardiovascular activities of the African catfish embryos/larvae (Clarias gariepinus)

Ecotoxicology and Environmental Safety, 2021
Acetaminophen is a widely used analgesic that has been detected in many water bodies with few reports concerning its potential toxicity to fish. This study sought to assess the developmental, swimming performance and cardiovascular activities of embryo ...
Nosakhare Osazee Erhunmwunse, Isioma Tongo, Lawrence Ikechukwu Ezemonye   +2 more
doaj   +1 more source

Acetaminophen-induced hypotension in sepsis

Journal of Pharmaceutical Health Care and Sciences, 2022
Background Acetaminophen-induced hypotension has been reported in critically ill patients; however, it remains unclear whether mannitol, present as a stabilizing compound in acetaminophen formulations, affects hemodynamic changes.
Shunsuke Inage, Ryo Yajima, Shintaro Nagahara, Aya Kazama, Moe Takamura, Tomohiro Shoji, Mika Kadoi, Yukiko Tashiro, Yuya Ise   +8 more
doaj   +1 more source

Macrophage migration inhibitory factor as a potential biomarker in acetaminophen overdose: a pilot study

Toxicology Communications, 2022
Acetaminophen overdose is a leading cause of liver failure in the United States. Macrophage migration inhibitory factor (MIF) is a cytokine that is released early and promotes acetaminophen toxicity in preclinical models.
Joshua Bloom, Teddy Uzamere, Yasmin Hurd, Alex F. Manini   +3 more
doaj   +1 more source

Delayed Acetaminophen Absorption Resulting in Acute Liver Failure

Case Reports in Critical Care, 2022
Introduction. Acetaminophen is a common medication involved in deliberate and accidental self-poisoning. The acetaminophen treatment nomogram is used to guide acetylcysteine treatment.
Huiling Tan, Paul Stathakis, Benoj Varghese, Nicholas A. Buckley, Angela L. Chiew   +4 more
doaj   +1 more source

Use of Arctium lappa Extract Against Acetaminophen-Induced Hepatotoxicity in Rats

Current Therapeutic Research, 2015
Background: Severe destructive hepatic injuries can be induced by acetaminophen overdose and may lead to acute hepatic failure. Objective: To investigate the ameliorative effects of Arctium lappa root extract on acetaminophen-induced hepatotoxicity ...
Attalla Farag El-Kott, PhD, Mashael Mohammed Bin-Meferij, PhD   +1 more
doaj   +1 more source

Effect of Saffron (Crocus sativus L.), as a Bioenhancer, on Pharmacokinetic of Acetaminophen: An Animal Study

Traditional and Integrative Medicine, 2023
In Traditional Persian Medicine (TPM) saffron is used as an accompaniment agent “Mobadreq” in poly herbal formulations. According to TPM texts, “Mobadreq” is a substance (or drug) which facilitates access of drugs or food to the whole body or specific ...
Seyede Nargess Sadati Lamardi, Mohammad Reza Shams Ardekani, Katayoon Mireskandari, Mohammad Sharifzadeh, Maryam Yakhchali, Sima Sadrai   +5 more
doaj   +1 more source

An evaluation on consumers' usage pattern of acetaminophen (paracetamol): A multicenter study from Penang, Malaysia

Archives of Pharmacy Practice, 2017
Background: Acetaminophen poisoning is becoming an increasingly common social problem in Malaysia. An understanding of consumers' usage pattern of acetaminophen is essential in addressing the issue of accidental acetaminophen poisoning.
Chee Ping Chong, Seak Fang Tan, Weng-Tink Chooi   +2 more
doaj   +1 more source