Results 31 to 40 of about 113,832 (239)

Conjugation of nitrated acetaminophen to Der p1 amplifies peripheral blood monocyte response to Der p1.

PLoS ONE, 2017
BACKGROUND:An association of acetaminophen use and asthma was observed in the International Study of Asthma and Allergies in Childhood study. However there are no clear mechanisms to explain an association between acetaminophen use and immunologic ...
Ryan G Thomas, Brenda M Rivera Reyes, Benjamin M Gaston, Nelki B Rivera Acosta, Ilya R Bederman, Laura A Smith, Morgan T Sutton, Benlian Wang, John F Hunt, Tracey L Bonfield   +9 more
doaj   +1 more source

Adverse effect profile comparison of pain regimens with and without intravenous acetaminophen in total hip and knee arthroplasty patients

SAGE Open Medicine, 2017
Background: The use of adjunct, non-opioid agents is integral for pain control following total hip and knee arthroplasty. Literature comparing safety profiles of intravenous acetaminophen versus opioids is lacking.
Alyssa Gallipani, A Scott Mathis, Hoytin Lee Ghin, Germin Fahim   +3 more
doaj   +1 more source

Acetaminophen (Paracetamol) [PDF]

Journal of Pain and Symptom Management, 2013
Therapeutic Reviews aim to provide essential independent information for health professionals about drugs used in palliative and hospice care. Additional content is available on www.palliativedrugs.com. Country-specific books (Hospice and Palliative Care Formulary USA, and Palliative Care Formulary, British and Canadian editions) are also available and
Robert, Twycross, Victor, Pace, Mary, Mihalyo, Andrew, Wilcock   +3 more
openaire   +2 more sources

Integration of Placental Transfer in a Fetal–Maternal Physiologically Based Pharmacokinetic Model to Characterize Acetaminophen Exposure and Metabolic Clearance in the Fetus

Clinical Pharmacokinetics, 2020
Background and Objective Although acetaminophen is frequently used during pregnancy, little is known about fetal acetaminophen pharmacokinetics. Acetaminophen safety evaluation has typically focused on hepatotoxicity, while other events (fetal ductal ...
P. Mian, K. Allegaert, S. Conings, P. Annaert, D. Tibboel, M. Pfister, K. Van Calsteren, J. N. van den Anker, A. Dallmann   +8 more
semanticscholar   +1 more source

Using a decision tree algorithm to distinguish between repeated supra-therapeutic and acute acetaminophen exposures

BMC Medical Informatics and Decision Making, 2023
Background This study aimed to compare clinical and laboratory characteristics of supra-therapeutic (RSTI) and acute acetaminophen exposures using a predictive decision tree (DT) algorithm.
Omid Mehrpour, Christopher Hoyte, Samaneh Nakhaee, Bruno Megarbane, Foster Goss   +4 more
doaj   +1 more source

Acetaminophen Overdose as a Potential Risk Factor for Parkinson's Disease

Clinical and Translational Science, 2019
Four complementary approaches were used to investigate acetaminophen overdose as a risk factor for Parkinson's disease (PD). Circulating microRNAs (miRNAs) serum profiles from acetaminophen‐overdosed patients were compared with patients with terminal PD,
Sacha Bohler, Xiaosong Liu, Julian Krauskopf, Florian Caiment, Jiri Aubrecht, Gerry A. F. Nicolaes, Jos C. S. Kleinjans, Jacco J. Briedé   +7 more
doaj   +1 more source

Acetaminophen Use Concomitant with Long-Lasting Flucloxacillin Therapy: A Dangerous Combination

European Journal of Case Reports in Internal Medicine, 2020
Acetaminophen and flucloxacillin both interfere with the ?-glutamyl cycle. Long-lasting concomitant use of flucloxacillin and acetaminophen can lead to 5-oxoproline accumulation and severe high anion gap metabolic acidosis.
Luuk René van den Bersselaar, Judith Maria Dimphena van den Brule, Johannes Gerardus van der Hoeven   +2 more
doaj   +1 more source

Association of Prenatal Acetaminophen Exposure Measured in Meconium With Adverse Birth Outcomes in a Canadian Birth Cohort

Frontiers in Pediatrics, 2022
BackgroundThe small number of studies examining the association of prenatal acetaminophen with birth outcomes have all relied on maternal self-report.
Brennan H. Baker, Heather H. Burris, Tessa R. Bloomquist, Amélie Boivin, Virginie Gillet, Annie Larouche, Larissa Takser, Larissa Takser, Jean-Philippe Bellenger, Jean-Charles Pasquier, Andrea A. Baccarelli   +10 more
doaj   +1 more source

Public awareness of acetaminophen and risks of drug induced liver injury: Results of a large outpatient clinic survey.

PLoS ONE, 2020
Acetaminophen is one of the most commonly consumed analgesics world wide. Generally perceived as a safe medication, it is the most common cause of acute liver failure in the United States with inadvertent hepatotoxicity in half of all cases. We therefore
Robert A Mitchell, Sahaj Rathi, Monica Dahiya, Julie Zhu, Trana Hussaini, Eric M Yoshida   +5 more
doaj   +1 more source

Attenuation of copaiba oil in hepatic damage in rats [PDF]

Acta Cirúrgica Brasileira, 2014
PURPOSE: To investigate the copaiba oil on the hepatic damage induced by acetaminophen, comparing against corn oil. METHODS: Fifty four rats were distributed into nine study groups (N=6): control group, that didn't receive the acetaminophen ...
Marcus Vinicius Henriques Brito, Felipe D'Almeida Costa, Diego Matos de Vasconcelos, Lauro Augusto Veloso Costa, Edson Yuzur Yasojima, Renan Kleber Costa Teixeira, Vitor Nagai Yamaki   +6 more
doaj   +1 more source