Results 81 to 90 of about 1,685,259 (292)

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Effect of vitamin C and quercetin treatment on the liver histopathologic profile in congenital lead exposed male rat pups [PDF]

, 2015
Introduction: Lead is one of the most important environmental pollutants due to its vast use in various industries. Lead accumulation in different organs, especially the brain, liver and kidneys can cause serious health problems.
Beheshti, N., Ganji, F., Sepehri, H.
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Semiconductive and Photoconductive Properties of the Single Molecule Magnets Mn$_{12}$-Acetate and Fe$_8$Br$_8$

, 2003
Resistivity measurements are reported for single crystals of Mn$_{12}$-Acetate and Fe$_8$Br$_8$. Both materials exhibit a semiconductor-like, thermally activated behavior over the 200-300 K range.
A. Lascialfari, A. Mukhin, A. Mukhin, A.B. Sushkov, A.B. Sushkov, A.L. Barra, A.M. Gomes, C. Sangregorio, D. Arcon, D. L. Eaton, D. Zipse, E. Jobiliong, E. S. Choi, E.M. Chudnovsky, E.M. Chudnovsky, F. Fominaya, F. Luis, I. Mirebeau, J. Dolinsek, J. M. North, J. S. Brooks, J.A.A.J. Perenboom, J.F. Fernandez, J.M. North, J.M. North, J.R. Friedman, K. Park, K. Park, K. Weighardt, K.M. Mertes, L. Bokacheva, L. Thomas, M. Dressel, M. Hennion, M. I. Katsnelson, M. Sales, M.N. Leuenberger, M.R. Pederson, M.R. Pederson, N. S. Dalal, R. Blinc, R. Caciuffo, R.M. Achey, R.M. Achey, R.M. Achey, S. Carretta, S. Hill, S. Hill, S.M. Oppenheimer, S.M.J. Aubin, T. Goto, T. Kubo, T. Lis, T. Tokumoto, W. Wernsdofer, W. Wernsdorfer, Y. Furukawa, Y. Furukawa, Z. Kutnjak, Z. Zeng   +59 more
core   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

The interplay between gut microbiota, short-chain fatty acids, and implications for host health and disease

Gut Microbes
Short-chain fatty acids (SCFAs) – acetate, propionate, and butyrate – are important bacterial fermentation metabolites regulating many important aspects of human physiology.
Kallie E. Hays, Jacob M. Pfaffinger, Rebecca Ryznar   +2 more
doaj   +1 more source

Competition for Hydrogen Prevents Coexistence of Human Gastrointestinal Hydrogenotrophs in Continuous Culture

Frontiers in Microbiology, 2020
Understanding the metabolic dynamics of the human gastrointestinal tract (GIT) microbiota is of growing importance as research continues to link the microbiome to host health status.
Nick W. Smith, Nick W. Smith, Nick W. Smith, Nick W. Smith, Paul R. Shorten, Paul R. Shorten, Eric Altermann, Eric Altermann, Nicole C. Roy, Nicole C. Roy, Nicole C. Roy, Nicole C. Roy, Warren C. McNabb, Warren C. McNabb   +13 more
doaj   +1 more source

Liquid and vapour phase of lavandin (Lavandula × intermedia) essential oil: chemical composition and antimicrobial activity [PDF]

, 2019
Essential oils from Lavandula genus and the obtained hybrids are widely used for different purposes such as perfume production in the cosmetic field and for its biological properties.
Garzoli, S., Giacomello, P., Masci, V. L., Ovidi, E., Tiezzi, A., Turchetti, G.   +5 more
core   +1 more source

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source

Phase Equilibria for Quaternary Mixtures in Esterification Reaction Systems [PDF]

, 2003
This paper examines the effect of the simultaneous chemical and phase equilibrium on the conceptual design of reactive distillation processes. Esterification of acetic acid with methanol, ethanol and butanol are examined.
Campanella, Enrique Angel, Mandagaran, Beatriz Adriana   +1 more
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