Results 1 to 10 of about 179,024 (208)

Bacteroides methylmalonyl-CoA mutase produces propionate that promotes intestinal goblet cell differentiation and homeostasis.

Cell Host and Microbe, 2023
Propionate is a short-chain fatty acid that is generated upon microbiome-mediated fiber fermentation in the intestine. By modulating immune and metabolic pathways, propionate exerts many health benefits.
Xingyu Wang, Zhongle Cai, Qiaoling Wang, Chao Wu, Yingkai Sun, Zhifeng Wang, Xiaoqiang Xu, Wenzhi Xue, Zhiwen Cao, Minchun Zhang, Yinmeng Zhu, Huibin Lin, Yi Zhang, Mingyang Yuan, Yuxiao Zhao, Aibo Gao, Yu-Hong Yu, Yufang Bi, Guang Ning, Weiqing Wang, Jiqiu Wang, Ruixin Liu   +21 more
semanticscholar   +1 more source

The enol of propionic acid

Chemical Communications, 2023
We demonstrate the gas-phase synthesis of prop-1-ene-1,1-diol, the hitherto unreported higher energy tautomer of propionic acid.
Akkad Danho, Artur Mardyukov, Peter R. Schreiner   +2 more
openaire   +2 more sources

Sources of propionate in inborn errors of propionate metabolism

Metabolism, 1990
Amino acids are widely regarded as the most important sources of propionate in disorders of propionate metabolism. Propionate production was measured in the fasting state by continuous infusion of sodium [1-13C]propionate in three children with methylmalonic acidemia (MMA) and three with propionic acidemia (PA).
G N, Thompson, J H, Walter, J L, Bresson, G C, Ford, S L, Lyonnet, R A, Chalmers, J M, Saudubray, J V, Leonard, D, Halliday   +8 more
openaire   +2 more sources

Propionate Ameliorates Alcohol-Induced Liver Injury in Mice via the Gut-Liver Axis: Focus on the Improvement of Intestinal Permeability.

Journal of Agricultural and Food Chemistry, 2022
Alcohol-related liver disease (ALD) is a major cause of chronic liver disease worldwide with limited therapeutic options. Here, we first revealed the promising beneficial effect of gut microbiota-derived propionate on alcoholic liver injury in mice. This
Qi Xu, Renshuai Zhang, Y. Mu, Yue Song, Na Hao, Yunbo Wei, Quanbo Wang, Charles R. Mackay   +7 more
semanticscholar   +1 more source

Survey of baked goods for propionic acid and propionates

Food Additives and Contaminants, 1996
One hundred and thirty samples comprising bread (64), hamburger buns (33), pittas (16), cakes (9) and Christmas puddings (8) from various retail outlets in the UK, have been analysed for the preservative propionic acid. Only one sample of bread, two samples of hamburger buns and three samples of pitta contained propionic acid in excess of 1000 mg/kg ...
M J, Scotter, S A, Thorpe, S L, Reynolds, L A, Wilson, P R, Strutt   +4 more
openaire   +2 more sources

Measurement of propionate turnover in vivo using sodium [2H5]propionate and sodium [13C]propionate

Clinica Chimica Acta, 1989
The outcome for children with inherited disorders of propionate metabolism is poor. To facilitate development of improved treatment in these conditions, we described techniques for the estimation of the rate of production and removal of propionate in vivo.
J H, Walter, G N, Thompson, J V, Leonard, C S, Heatherington, K, Bartlett   +4 more
openaire   +2 more sources

Short-chain fatty acids, acetate and propionate, directly upregulate osteoblastic differentiation

International Journal of Food Science and Nutrition, 2022
Short-chain fatty acids, including acetate, propionate, and butyrate are metabolites of dietary fibre produced by microbiota in the large intestine, have been proposed to contribute to effects on bone homeostasis.
Takashi Kondo, T. Chiba, Yuko Tousen
semanticscholar   +1 more source

The pathway of propionate oxidation

Biochimica et Biophysica Acta, 1953
Abstract 1. 1. The oxidation of labelled propionate in the presence of large pools of unlabelled l -lactate, d -lactate and pyruvate gives rise to the appearance of label in these pools. The appearance of label suggests that the compounds mentioned are in equilibrium with the actual intermediates.
H R, MAHLER, F M, HUENNEKENS
openaire   +2 more sources

Cardiomyopathy in propionic acidaemia

European Journal of Pediatrics, 1993
Following the death of a patient with propionic acidaemia with a cardiomyopathy we reviewed 19 patients with the same disorder for evidence of cardiomyopathy. Six patients were found to meet the diagnostic criteria. Three patients died and in the other three the cardiac disease resolved completely.
A F, Massoud, J V, Leonard
openaire   +2 more sources

Propionate promotes ferroptosis and apoptosis through mitophagy and ACSL4-mediated ferroptosis elicits anti-leukemia immunity.

Free Radical Biology & Medicine
Short-chain fatty acids (SCFAs), particularly propionate and butyrate, have been reported in many cancers. However, the relationship between propionate and acute myeloid leukemia (AML) remains unclear.
Yihong Wei, Wancheng Liu, Ruiqing Wang, Yuhong Chen, Jinting Liu, Xiaodong Guo, Candan Can, Xinyu Yang, Dongmei Wang, Xiang Hu, Daoxin Ma   +10 more
semanticscholar   +1 more source