Results 11 to 20 of about 204,518 (306)

Propionate Alleviates Abdominal Aortic Aneurysm by Modulating Colonic Regulatory T-Cell Expansion and Recirculation

JACC: Basic to Translational Science, 2022
Summary: Emerging evidence supports that intestinal microbial metabolite short-chain fatty acids (SCFAs) increase the pool of regulatory T cells (Tregs) in the colonic lamina propria (cLP) and protect against nonintestinal inflammatory diseases, such as ...
Fen Yang, MD, Ni Xia, MD, PhD, Shuang Guo, MD, Jiyu Zhang, MS, Yuhan Liao, MS, Tingting Tang, MD, PhD, Shaofang Nie, MD, PhD, Min Zhang, MD, PhD, Bingjie Lv, MD, Yuzhi Lu, MD, PhD, Jiao Jiao, MD, PhD, Jingyong Li, MD, PhD, Weimin Wang, PhD, Desheng Hu, MD, PhD, Xiang Cheng, MD, PhD   +14 more
doaj   +1 more source

The Short-Chain Fatty Acids Propionate and Butyrate Augment Adherent-Invasive Escherichia coli Virulence but Repress Inflammation in a Human Intestinal Enteroid Model of Infection

Microbiology Spectrum, 2021
Short-chain fatty acids (SCFAs), which consist of six or fewer carbons, are fermentation products of the bacterial community that inhabits the intestine.
Fernanda Pace, Sara E. Rudolph, Ying Chen, Bin Bao, David L. Kaplan, Paula I. Watnick   +5 more
doaj   +1 more source

Overexpression of GPR41 attenuated glucose production in propionate-induced bovine hepatocytes

Frontiers in Veterinary Science, 2022
Bovine liver mainly utilizes the propionate as a gluconeogenic substrate to synthesize the glucose. However, the mechanism underlying the regulatory effects of propionate on the glucose production in bovine hepatocytes remains less known.
Miao Lin, Miao Lin, Miao Lin, Maocheng Jiang, Tianyu Yang, Guoqi Zhao, Guoqi Zhao, Guoqi Zhao, Kang Zhan, Kang Zhan, Kang Zhan   +10 more
doaj   +1 more source

Increased colonic propionate reduces anticipatory reward responses in the human striatum to high-energy foods [PDF]

, 2016
Background: Short-chain fatty acids (SCFAs), metabolites produced through the microbial fermentation of nondigestible dietary components, have key roles in energy homeostasis.
Alhabeeb, Habeeb, Busza, Albert, Byrne, Claire S., Chambers, Edward S., Chhina, Navpreet, Fitzpatrick, Julie, Fountana, Sofia, Frost, Gary S., Garcia-Perez, Isabel, Goldstone, Anthony P., Holmes, Elaine, Irani, Cherag, Morrison, Douglas J., Preston, Tom, Tedford, Catriona   +14 more
core   +1 more source

Acute oral sodium propionate supplementation raises resting energy expenditure and lipid oxidation in fasted humans [PDF]

, 2018
Short chain fatty acids (SCFAs), produced from fermentation of dietary fibre by the gut microbiota, have been suggested to modulate energy metabolism. Previous work using rodent models have demonstrated that oral supplementation of the SCFA propionate ...
Baldwin, Besten, Boets, Canfora, Canfora, Chambers, Chandramouli, De Vadder, Flint, Frayn, Ge, Kimura, Kimura, Kummitha, Ludwig, Morrison, Peters, Psichas, Ridaura, Weir   +19 more
core   +1 more source

The molecular mechanism of propionate-regulating gluconeogenesis in bovine hepatocytes [PDF]

Animal Bioscience, 2023
Objective Cows that are nursing get around 80% of their glucose from liver gluconeogenesis. Propionate, a significant precursor of liver gluconeogenesis, can regulate the key genes involved in hepatic gluconeogenesis expression, but its precise effects ...
Rui Pang, Xiao Xiao, Tiantian Mao, Jiajia Yu, Li Huang, Wei Xu, Yu Li, Wen Zhu   +7 more
doaj   +1 more source

The lung function profile of once-daily tiotropium and olodaterol via Respimat® is superior to that of twice-daily salmeterol and fluticasone propionate via Accuhaler® (ENERGITO® study) [PDF]

, 2016
Background: Tiotropium + olodaterol has demonstrated improvements beyond lung function benefits in a large Phase III clinical program as a once-daily maintenance treatment for COPD and may be a potential option for the initiation of maintenance treatment
Beeh, Kai-Michael, Bjermer, Leif,, Derom, Eric, Echave-Sustaeta, José, Grönke, Lars, Hamilton, Alan, Lund University., Lund University., Zhai, Dongmei   +8 more
core   +2 more sources

Safety and efficacy of fluticasone propionate in the topical treatment of skin diseases [PDF]

, 2004
Fluticasone propionate - the first carbothioate corticosteroid - has been classified as a potent anti-inflammatory drug for dermatological use. It is available as 0.05% cream and 0.005% ointment formulations for the acute and maintenance treatment of ...
Atsuta J, Boner AL, Bridgman A, Callen J, Delescluse J, Dooms-Goossens AE, Dykes PJ, Falcoz C, Fisher DA, Goossens A, Harding SM, Hogger P, James M, Johnson M, Johnson M, Juhlin L, Katz HI, Korting HC, Lebwohl M, Li JT, Liu XQ, Llewellyn-Jones CG, Lucky AW, McKenzie AW, McLean HM, Nurnberger FG, Phillipps GH, Roberts DT, Spencer CM, Tharp MD, Venning VA, Wilkinson SM, Wolkerstorfer A, Young MMR   +33 more
core   +1 more source

Systemic availability and metabolism of colonic-derived short-chain fatty acids in healthy subjects: a stable isotope study [PDF]

, 2016
The short-chain fatty acids (SCFAs), acetate, propionate and butyrate, are bacterial metabolites that mediate the interaction between the diet, the microbiota and the host.
Annaert, Pieter, Boets, Eef, Courtin, Christophe M., De Preter, Vicky, De Vuyst, Luc, Delcour, Jan A., Deroover, Lise, Gomand, Sara V., Hamer, Henrike M., Preston, Tom, Van den Mooter, Guy, Verbeke, Kristin A., Vermeulen, Karen   +12 more
core   +1 more source

Temporal Microbial Community Dynamics in Microbial Electrolysis Cells – Influence of Acetate and Propionate Concentration

Frontiers in Microbiology, 2017
Microbial electrolysis cells (MECs) are widely considered as a next generation wastewater treatment system. However, fundamental insight on the temporal dynamics of microbial communities associated with MEC performance under different organic types with ...
Ananda Rao Hari, Krishnaveni Venkidusamy, Krishna P. Katuri, Samik Bagchi, Pascal E. Saikaly   +4 more
doaj   +1 more source