Results 101 to 110 of about 34,477 (255)

Identifying Drugs Associated With Parkinson's Disease Risk Using Machine Learning

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Machine learning (ML)–based methods have been proposed as a potential approach for identifying candidate drugs to be repurposed as disease‐modifying treatments for Parkinson's disease (PD). We applied an ML‐based signal detection method to identify drugs associated with PD and evaluated the method's generalizability.
Eeva Pylkkö, Émeline Courtois, Anne Paakinaho, Sirpa Hartikainen, Valtteri Kaasinen, Alexis Elbaz, Anne C. M. Thiébaut, Ismaïl Ahmed, Anna‐Maija Tolppanen   +8 more
wiley   +1 more source

Brain Edema Formation and Functional Outcome After Surgical Decompression in Murine Closed Head Injury Are Modulated by Acetazolamide Administration

Frontiers in Neurology, 2019
Acetazolamide (ACZ), carbonic anhydrase inhibitor, has been successfully applied in several neurosurgical conditions for diagnostic or therapeutic purposes. Furthermore, neuroprotective and anti-edematous properties of ACZ have been postulated.
Jacek Szczygielski, Jacek Szczygielski, Jacek Szczygielski, Vanessa Hubertus, Vanessa Hubertus, Eduard Kruchten, Eduard Kruchten, Andreas Müller, Lisa Franziska Albrecht, Angelika E. Mautes, Karsten Schwerdtfeger, Joachim Oertel   +11 more
doaj   +1 more source

Possible association between acetazolamide administration during pregnancy and multiple congenital malformations

Drug Design, Development and Therapy, 2016
Afnan I Al-Saleem,1 Asma M Al-Jobair21Dental Department, Prince Sultan Military Medical City, Riyadh, Saudi Arabia; 2Department of Pediatric Dentistry and Orthodontics, College of Dentistry, King Saud University, Riyadh, Saudi ArabiaAbstract: Congenital ...
Al-Saleem AI, Al-Jobair AM
doaj  

Effectiveness of Topiramate Versus Acetazolamide in the Management of Idiopathic Intracranial Hypertension: ASystematic Review and Meta-Analysis

Medicina
Background and Objectives: Primary pseudotumor cerebri syndrome, another name for idiopathic intracranial hypertension (IIH), is a neurological condition marked by elevated intracranial pressure (ICP) that can result in papilledema without a known ...
Abdullah Almaqhawi, Alia Alokley, Reham Alamri, Razan Alabdulqader, Ahmad Alali, Ayat Aleid, Amani Alhejji, Maryam N. ALNasser   +7 more
doaj   +1 more source

Mäestikuhaigus [PDF]

, 2017
Seoses seiklusreiside populaarsemaks muutumisega ei ole mäestikuhaigus tänapäeval enam ainuüksi alpinistide probleem, vaid see võib tabada ka n-ö tavalist inimest.
Poots, Marja
core   +2 more sources

Endolymphatic Hydrops Reversal following Acetazolamide Therapy: Demonstration with Delayed Intravenous Contrast-Enhanced 3D-FLAIR MRI [PDF]

, 2015
Ali R. Sepahdari, Nopawan Vorasubin, Gail Ishiyama, Akira Ishiyama   +3 more
openalex   +1 more source

Acetazolamide in Vestibulocerebellar Syndrome

Pediatric Neurology Briefs, 1991
Five patients with long-standing episodic vertigo and ocular motor signs are reported from the Department of Neurology, UCLA School of Medicine, Los Angeles, CA.
J Gordon Millichap
doaj   +1 more source

Effect of acetazolamide and subsequent ventriculo-peritoneal shunting on clinical signs and ventricular volumes in dogs with internal hydrocephalus [PDF]

, 2015
Background: Acetazolamide is recommended for the reduction of cerebrospinal fluid production in canine internal hydrocephalus. The efficacy of the drug in terms of alleviation of the clinical symptoms and the restoration of normal ventricular volume has ...
Kolecka, Malgorzata, Kramer, Martin, Moritz, Andreas, Ondreka, Nele, Schmidt, Martin J.   +4 more
core   +2 more sources

P277Comparison of changes in the plasma volume and renal function between acetazolamide vs. conventional diuretics: understanding their mechanical differences according to the chloride theory [PDF]

, 2018
Hajime Kataoka
openalex   +1 more source

Effects of acetazolamide on kidney function in Type 1 (insulin-dependent) diabetic patients with diabetic nephropathy [PDF]

, 1988
P. Sk�tt, E. Hommel, Niels Eske Bruun, S. Arnold‐Larsen, H.‐H. Parving   +4 more
openalex   +1 more source