Results 21 to 30 of about 29,036 (224)

Carbonic anhydrase inhibitor acetazolamide shifts synaptic vesicle recycling to a fast mode at the mouse neuromuscular junction [PDF]

open access: yes, 2017
Acetazolamide (AZ), a molecule frequently used to treat different neurological syndromes, is an inhibitor of the carbonic anhydrase (CA), an enzyme that regulates pH inside and outside cells.
Bertone Cueto, Nicolás Iván   +5 more
core   +1 more source

Structural and Vibrational Study on Monomer and Dimer Forms and Water Clusters of Acetazolamide

open access: yesJournal of Spectroscopy, 2013
Experimental IR and Raman spectra of solid acetazolamide have been analysed by computing the molecular structures and vibrational spectra of monomer and dimer forms and water clusters of acetazolamide. The possible stable conformers of free acetazolamide
Aysen E. Ozel   +3 more
doaj   +1 more source

Acetazolamide for Bipolar Disorders: A Scoping Review

open access: yesBrain Sciences, 2023
Acetazolamide, a carbonic anhydrase inhibitor, is used to treat a variety of ailments. It has been highlighted for its potential to benefit people with bipolar disorders, for whom there are clear current unmet treatment needs.
Rebecca Strawbridge   +3 more
doaj   +1 more source

Autoimmune hyperphosphatemic tumoral calcinosis in a patient with FGF23 autoantibodies [PDF]

open access: yes, 2018
Hyperphosphatemic familial tumoral calcinosis (HFTC)/hyperostosis-hyperphosphatemia syndrome (HHS) is an autosomal recessive disorder of ectopic calcification due to deficiency of or resistance to intact fibroblast growth factor 23 (iFGF23). Inactivating
Burbelo   +14 more
core   +1 more source

Benzolamide improves oxygenation and reduces acute mountain sickness during a high-altitude trek and has fewer side effects than acetazolamide at sea level. [PDF]

open access: yes, 2017
Acetazolamide is the standard carbonic anhydrase (CA) inhibitor used for acute mountain sickness (AMS), however some of its undesirable effects are related to intracellular penetrance into many tissues, including across the blood-brain barrier ...
Collier, DJ   +6 more
core   +1 more source

Adverse events associated with intraocular injection of anti-VEGF(bevacizumab) in retinal vein ccclusion: a case report [PDF]

open access: yes, 2015
Introduction: Antiangiogenic agents are often administered for treatment of Branch Retinal Vein Occlusion (BRVO). Among them, Bevacizumab has noticeable antiangiogenic and antiedemigenic properties and possesses great capacity to penetrate the retinal ...
ARTICO, Marco   +7 more
core   +1 more source

Keratoprostheses for corneal blindness: a review of contemporary devices [PDF]

open access: yes, 2015
According to the World Health Organization, globally 4.9 million are blind due to corneal pathology. Corneal transplantation is successful and curative of the blindness for a majority of these cases. However, it is less successful in a number of diseases
Avadhanam, Venkata   +2 more
core   +1 more source

Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment of Neisseria gonorrhoeae

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2022
Neisseria gonorrhoeae is a high-priority pathogen of concern due to the growing prevalence of resistance development against approved antibiotics. Herein, we report the anti-gonococcal activity of ethoxzolamide, the FDA-approved human carbonic anhydrase ...
Nader S. Abutaleb   +8 more
doaj   +1 more source

Cerebrovascular reserve in moyamoya disease: relation to cerebral blood flow, capillary dysfunction, oxygenation, and energy metabolism

open access: yesFrontiers in Neurology, 2023
BackgroundCerebral hemodynamics in moyamoya disease (MMD) is complex and needs further elucidation. The primary aim of the study was to determine the association of the cerebrovascular reserve (CVR) with cerebral blood flow (CBF) disturbances, oxygen ...
Teodor Svedung Wettervik   +4 more
doaj   +1 more source

Effects of acetazolamide on control of breathing in sleep apnea patients: Mechanistic insights using meta‐analyses and physiological model simulations

open access: yesPhysiological Reports, 2021
Obstructive and central sleep apnea affects ~1 billion people globally and may lead to serious cardiovascular and neurocognitive consequences, but treatment options are limited.
Christopher N. Schmickl   +6 more
doaj   +1 more source

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