Results 51 to 60 of about 32,023 (271)

Synthesis, Characterization, Biological Properties, and Sensor Applications of Novel Thiosemicarbazone Derivatives

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT In this study, novel thiosemicarbazone derivative molecules (5a–j) were synthesized. The characterization of the synthesized molecules was carried out using 1H–, 13C–NMR, FT–IR, and Q–TOF spectroscopic techniques. Then, the inhibitory effect of these compounds was examined for human carbonic anhydrase I and II (hCA I, and II) and ...
Hayreddin Gezegen, Oguz Özbek, Meryem Topal, Hatice Şahin, Ümit M. Koçyiğit   +4 more
wiley   +1 more source

Acetazolamide as an Add-on Therapy Following Barbed Reposition Pharyngoplasty in Obstructive Sleep Apnea: A Randomized Controlled Trial

Life
Surgical interventions, like barbed reposition pharyngoplasty (BRP), are a valuable alternative for patients with obstructive sleep apnea (OSA) who are unable to tolerate continuous positive airway pressure (CPAP).
Simon Hellemans, Eli Van de Perck, Dorine Van Loo, Johan Verbraecken, Scott A. Sands, Ali Azarbarzin, Marijke Dieltjens, Sara Op De Beeck, Anneclaire Vroegop, Olivier M. Vanderveken   +9 more
doaj   +1 more source

Mind the Gap: Acetazolamide Prolonged Periods without Paralysis in a Girl with Andersen-Tawil Syndrome

Case Reports in Neurology, 2021
We present a case report of a 13-year-old girl with Andersen-Tawil Syndrome (ATS), a rare genetic disorder which is characterized by dysmorphic features, ventricular arrhythmias, and frequent episodes of muscle paralysis that interfere with daily ...
Nina Žakelj, Damjan Osredkar, Nataša Šuštar   +2 more
doaj   +1 more source

Question Answering with Subgraph Embeddings [PDF]

, 2014
This paper presents a system which learns to answer questions on a broad range of topics from a knowledge base using few hand-crafted features. Our model learns low-dimensional embeddings of words and knowledge base constituents; these representations ...
Bordes, Antoine, Chopra, Sumit, Weston, Jason   +2 more
core   +2 more sources

Annual Banned‐Substance Review 17th Edition—Analytical Approaches in Human Sports Drug Testing 2023/2024

Drug Testing and Analysis, EarlyView.
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario  Thevis, Tiia  Kuuranne, Hans  Geyer   +2 more
wiley   +1 more source

GC-NICI-MS analysis of acetazolamide and other sulfonamide (R-SO2-NH2) drugs as pentafluorobenzyl derivatives [R-SO2-N(PFB)2] and quantification of pharmacological acetazolamide in human urine

Journal of Pharmaceutical Analysis, 2020
Acetazolamide (molecular mass (MM), 222) belongs to the class of sulfonamides (R-SO2-NH2) and is one of the strongest pharmacological inhibitors of carbonic anhydrase activity. Acetazolamide is excreted unchanged in the urine.
Olga Begou, Kathrin Drabert, Georgios Theodoridis, Dimitrios Tsikas   +3 more
doaj  

Early diuretic response and outcome prediction in ambulatory worsening heart failure: Natriuresis versus diuresis

ESC Heart Failure, EarlyView.
Abstract Aims Early diuresis and natriuresis are commonly used to assess the efficacy of decongestive therapy following an acute heart failure episode. There is limited knowledge regarding which parameter better predicts adverse clinical outcomes, especially in the outpatient setting.
M. Cobo Marcos, R. de la Espriella, I. Zegri‐Reiriz, P. Llacer, J. Rubio Gracia, J. Comín‐Colet, J. L. Morales‐Rull, P. Diez‐Villanueva, J. de Juan Bagudá, S. Jiménez‐Marrero, C. Ortiz Cortés, M. A. Restrepo‐Córdoba, J. M. García‐Pinilla, E. Barrios, S. del Prado Díaz, J. Núñez   +15 more
wiley   +1 more source

Novel cubosome based system for ocular delivery of acetazolamide

Drug Delivery, 2021
Acetazolamide is the drug of choice for glaucoma treatment in an emergency. However, it is not available in any topical formulation and it is available only as systemic tablets.
Hoda E. Teba, Islam A. Khalil, Heba M. El Sorogy   +2 more
doaj   +1 more source

Quantification of Carbonic Anhydrase Inhibitors and Metabolites in Urine and Hair of Patients and Their Relatives

Biology, 2022
Carbonic anhydrase inhibitors (CAIs) are prescription drugs also used in doping to dilute urine samples and tamper with urinalyses. Dorzolamide, brinzolamide, and acetazolamide are prohibited by the World Anti-Doping Agency.
Alfredo Fabrizio Lo Faro, Anastasio Tini, Giulia Bambagiotti, Filippo Pirani, Andrea Faragalli, Flavia Carle, Elena Pacella, Artan Ceka, Marco Moretti, Massimo Gottardi, Nicola Vito Lassandro, Michele Nicolai, Marco Lupidi, Cesare Mariotti, Francesco Paolo Busardò, Jeremy Carlier   +15 more
doaj   +1 more source

Rebound macular edema following oral acetazolamide therapy for juvenile X-linked retinoschisis in an Italian family [PDF]

, 2016
BACKGROUND: Juvenile X-linked retinoschisis (RS1, OMIM: 312700) is a hereditary vitreoretinal dystrophy characterized by bilateral foveal schisis and, in half of the patients, splitting through the nerve fiber layer in the peripheral retina. In the first
CUCCU, ALBERTO, FARCI, ROBERTA, FOSSARELLO, MAURIZIO, GALANTUOMO, MARIA SILVANA, Lorenz, B, NAPOLI, PIETRO EMANUELE, Preising, MN   +6 more
core   +2 more sources