Results 61 to 70 of about 34,477 (255)

Clinical outcomes of the PAUL glaucoma implant in primary open‐angle and pseudoexfoliative glaucoma eyes after failed glaucoma surgeries

Acta Ophthalmologica, EarlyView.
Abstract Purpose This study assesses the PAUL® glaucoma implant (PGI) in primary open angle glaucoma (POAG) and pseudoexfoliative glaucoma (PEXG) after failed glaucoma surgery. Given PEXG's more aggressive nature, limited research exists on PGI outcomes in this subgroup. This study aims to compare PGI's efficacy and safety in both conditions. Methods A
Constance Liegl, Leonie Bourauel, Benjamin Aretz, Diana Samarghitan, Wolfgang Walz, Michael Petrak, Frank G. Holz, Raffael Liegl, Karl Mercieca   +8 more
wiley   +1 more source

Phosphorylation and protonation of neighboring MiRP2 sites: function and pathophysiology of MiRP2-Kv3.4 potassium channels in periodic paralysis. [PDF]

, 2006
MinK-related peptide 2 (MiRP2) and Kv3.4 subunits assemble in skeletal muscle to create subthreshold, voltage-gated potassium channels. MiRP2 acts on Kv3.4 to shift the voltage dependence of activation, speed recovery from inactivation, suppress ...
Abbott, Geoffrey W, Butler, Margaret H, Goldstein, Steve AN   +2 more
core   +1 more source

Preclinical Evaluation of Ureidosulfamate Carbonic Anhydrase IX/XII Inhibitors in the Treatment of Cancers [PDF]

, 2019
Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues. Upregulation of the CAIX/XII isoforms is associated with hypoxic tumours and clinically linked with malignant progression, treatment ...
Gieling, Roben, Williams, Kaye J.
core   +2 more sources

Effects of acetazolamide on intracranial pressure and brain tissue oxygenation on patients with acute brain injury: A pilot physiological study

Physiological Reports
The effect of acetazolamide on regional brain tissue oxygenation in patients with acute brain injury (ABI) is unknown. We studied adult patients with ABI who received acetazolamide as per the treating physician's decision and had ICP and brain oxygen ...
Anas Hachlouf, Claudia Stella, Irene Cavalli, Elisa Gouvêa Bogossian, Sophie Schuind, Marco Anderloni, Fabio Silvio Taccone   +6 more
doaj   +1 more source

Effects of acetazolamide on exercise performance in patients with COPD going to high altitude: randomised controlled trial

ERJ Open Research
Background In patients with COPD, preventive treatment with acetazolamide reduces adverse health effects during altitude travel. We investigated whether preventive acetazolamide treatment modifies exercise performance in COPD patients going to high ...
Roman F. Kind, Michael Furian, Aline Buergin, Philipp M. Scheiwiller, Laura Mayer, Simon R. Schneider, Mona Lichtblau, Lara Muralt, Maamed Mademilov, Talant M. Sooronbaev, Silvia Ulrich, Konrad E. Bloch   +11 more
doaj   +1 more source

Treatment of acute cryptococcal meningitis in HIV infected adults, with an emphasis on resource-limited settings [PDF]

, 2018
BACKGROUND: Despite the advent and increasingly wide availability of antiretroviral therapy, cryptococcal meningitis (CM) remains a significant cause of mortality and morbidity amongst individuals with HIV infection in resource-limited settings.
Dedicoat, Martin, Dlamini, Sipho, Paul, Navin, Sloan, Derek   +3 more
core   +1 more source

Acetazolamide to treat symptomatic ruptured arachnoid cysts: illustrative cases [PDF]

, 2022
Isabella Watson, Patrick J. McDonald, Paul Steinbok, Brendon Graeber, Ash Singhal   +4 more
openalex   +1 more source

Incidence, risk factors, and outcomes of numerical hypotony and choroidal effusion following PRESERFLO MicroShunt implantation

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate the incidence, outcomes, and risk factors of numerical hypotony (NH) and choroidal effusion (CE) following standalone PRESERFLO MicroShunt (PMS) implantation. Methods Primary open‐angle glaucoma (POAG) and pseudoexfoliative glaucoma (PXG) patients with uni‐ or bilateral surgery at a tertiary university hospital were ...
Emil Nasyrov, Isabel Kommerell, Isabell Schleicher, David A. Merle, Caroline J. Wenzel, Bogomil Voykov   +5 more
wiley   +1 more source

Acetazolamide-induced bilateral ciliochoroidal effusion syndrome in plateau iris configuration

American Journal of Ophthalmology Case Reports, 2016
Purpose: Our purpose is to describe a 60-year-old male, who has plateau iris configuration and developed bilateral ciliochoroidal effusion syndrome after ingestion of acetazolamide.
Xiaofei Man, Raquel Costa, Bernadete M. Ayres, Sayoko E. Moroi   +3 more
doaj   +1 more source

Vitreoretinal complications and surgical outcomes in patients with X‐linked retinoschisis

Acta Ophthalmologica, EarlyView.
Abstract Purpose X‐linked retinoschisis (XLRS) is an inherited vitreoretinal disorder characterized by macular retinoschisis. In a subgroup of patients, peripheral retinoschisis can occur, potentially leading to complications such as vitreous haemorrhage (VH) and retinal detachment (RD).
Jonathan Hensman, Leo C. Hahn, Mary J. van Schooneveld, Roselie M. H. Diederen, Filip van den Broeck, Jacoline B. Ten Brink, Alberta A. Thiadens, Maria M. van Genderen, L. Ingeborgh van den Born, Bart P. Leroy, Carel B. Hoyng, Camiel J. F. Boon   +11 more
wiley   +1 more source