Results 71 to 80 of about 32,023 (271)

Treatment‐emergent central sleep apnoea managed by CPAP with adjunctive acetazolamide: A case report

Respirology Case Reports, 2022
Treatment‐emergent central sleep apnoea (TECSA) refers to the emergence of central apnoea during treatment for obstructive sleep apnoea (OSA), most commonly continuous positive airway pressure (CPAP).
Chin Tong Kwok, Kam Cheung Wong, Chun Lee Kwok, Sing Hang Lee, Kwok Sang Yee   +4 more
doaj   +1 more source

Phosphorylation and protonation of neighboring MiRP2 sites: function and pathophysiology of MiRP2-Kv3.4 potassium channels in periodic paralysis. [PDF]

, 2006
MinK-related peptide 2 (MiRP2) and Kv3.4 subunits assemble in skeletal muscle to create subthreshold, voltage-gated potassium channels. MiRP2 acts on Kv3.4 to shift the voltage dependence of activation, speed recovery from inactivation, suppress ...
Abbott, Geoffrey W, Butler, Margaret H, Goldstein, Steve AN   +2 more
core   +1 more source

Cognitive function and mood at high altitude following acclimatization and use of supplemental oxygen and adaptive servoventilation sleep treatments. [PDF]

, 2019
Impairments in cognitive function, mood, and sleep quality occur following ascent to high altitude. Low oxygen (hypoxia) and poor sleep quality are both linked to impaired cognitive performance, but their independent contributions at high altitude remain
Anza-Ramirez, Cecilia, Bosompra, Naa-Oye, DeYoung, Pamela N, Djokic, Matea A, Gilbertson, Dillon, Heinrich, Erica C, Malhotra, Atul, Orr, Jeremy E, Powell, Frank L, Simonson, Tatum S, Wu, Lu   +10 more
core   +2 more sources

High Genetic Diagnostic Yield for Patients with Rare Movement Disorders at a Single‐Center Neurogenetics Clinic

Movement Disorders Clinical Practice, EarlyView.
Abstract Background As advanced molecular testing is incorporated into routine clinical practice, accessibility and yield remain limited. Objectives We propose a simplified and effective workup strategy to maximize diagnostic yield based on presented diagnostic yield of rare movement disorders at a tertiary Neurogenetics Clinic.
Dvir Penn, Yam Amir, Gil Ben David, Alina Kuralop, Dalit Barel, Uri Hamiel, Michal Bach, Emil Elhanan, Tali Barkan, Daphna Marom, Adi Mory, Noga Simantov, Gadi Maayan Eshed, Achinoam Faust‐Socher, Vered Livneh, Avner Thaler, Nurit Omer, Tamara Shiner, Nir Giladi, Tanya Gurevich, Hagit Baris Feldman, Roy N. Alcalay, Yuval Yaron, Penina Ponger   +23 more
wiley   +1 more source

Effects of acetazolamide on sleep disordered breathing in pulmonary vascular disease: a randomised controlled trial

ERJ Open Research
Background Patients with pulmonary vascular disease (PVD) often suffer from nocturnal hypoxaemia, but also from sleep apnoea. Short-term use of acetazolamide increases ventilation due to metabolic acidosis and also reduces loop gain.
Esther I. Schwarz, Stéphanie Saxer, Mona Lichtblau, Simon R. Schneider, Julian Müller, Laura Mayer, Konrad E. Bloch, Silvia Ulrich   +7 more
doaj   +1 more source

High pseudotumor cerebri incidence in tretinoin and arsenic treated acute promyelocytic leukemia and the role of topiramate after acetazolamide failure

Leukemia Research Reports, 2014
Dual differentiation therapy with arsenic trioxide and tretinoin (all-trans-retinoic acid; ATRA) for the management of low and intermediate risk acute promyelocytic leukemia has recently been recommended by the National Comprehensive Cancer Network. Some
Morgan B. Smith, Elizabeth A. Griffiths, James E. Thompson, Eunice S. Wang, Meir Wetzler, Craig W. Freyer   +5 more
doaj   +1 more source

Targeting carbonic anhydrase IX improves the anti-cancer efficacy of mTOR inhibitors. [PDF]

, 2016
The inhibition of the mechanistic target of rapamycin complex 1 (mTORC1) by chemical inhibitors, such as rapamycin, has demonstrated anti-cancer activity in preclinical and clinical trials.
Datta, D., Demartines, N., Dormond, O., Faes, S., Horlbeck, J., Letovanec, I., Planche, A., Pythoud, C., Riggi, N., Santoro, T., Stehle, J.C., Uldry, E.   +11 more
core   +1 more source

Surgical Outcomes Comparison of Spontaneous Middle Cranial Fossa Cerebrospinal Fluid Leaks: Systematic Review and Meta‐analysis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Spontaneous cerebrospinal fluid (sCSF) leaks of lateral skull base have little consensus on optimal management. We synthesized and evaluated current literature via systematic and meta‐analysis to compare the success rates and complications of the different surgical techniques for middle cranial fossa (MCF) sCSF leak repair.
Dimitrios Spinos, Panagiotis Varoutis, Georgios Geropoulos, Georgios Vavoulis, Georgios Georgountzos, Nina Rafailia Karela, Manthia Papageorgakopoulou, Kyriacos Evangelou, Jameel Muzaffar, Wai Sum Cho   +9 more
wiley   +1 more source

Acetazolamide in prevention of altitude disease

Pedagogy and Psychology of Sport, 2020
Mountain climbing is associated with many risky, life-threatening situations. One of the most common attacking diseases at altitudes above 2500 m is altitude disease (HAI).
Paweł Choroszewicz, Anna Maria Dobosiewicz, Nataliia Badiuk   +2 more
doaj   +1 more source

Risk of Benign Paroxysmal Positional Vertigo Modified by Diuretics—A Population‐Level Case‐Control Study

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective This study aims to characterize diuretic use among patients with and without benign paroxysmal positional vertigo (BPPV) using a population‐level database. Study Design A case‐control study. Setting TriNetX US Collaborative Network. Methods Subjects with ≥1 hospital visit between 2019 and 2024 were queried and stratified by age (18 ...
Marwin Li, Rebecca C. Chiffer, Hongyan Li   +2 more
wiley   +1 more source