Results 191 to 200 of about 92,949 (326)

Design, Synthesis, and Antibacterial Properties of Dual-Ligand Inhibitors of Acetyl-CoA Carboxylase and Mechanism of Action for the Antibacterial Agent Moiramide B

, 2014
Molly A. Silvers
openalex   +2 more sources

Acetyl-CoA carboxylase 1 depletion suppresses de novo fatty acid synthesis and mitochondrial β-oxidation in castration-resistant prostate cancer cells [PDF]

, 2022
Shaoyou Liu, Jiarun Lai, Yuanfa Feng, Yangjia Zhuo, Hui Zhang, Yupeng Chen, Jinchuang Li, Xinyue Mei, Yanting Zeng, Jiaming Su, Yulin Deng, Funeng Jiang, Sheng-Bang Yang, Huijing Tan, Chi Tin Hon, Wei Sun, Zhaodong Han, Fen Wang, Weide Zhong   +18 more
openalex   +1 more source

The proteomic differences and expression of fatty acid‐binding protein 6 (FABP6) associated with gastrointestinal injury in horses with oral administration of a clinical dose of phenylbutazone

Equine Veterinary Journal, Volume 58, Issue 3, Page 845-856, May 2026.
Abstract Background Phenylbutazone (PBZ) can potentially induce gastrointestinal ulceration, and early detection of PBZ‐induced gastroenteropathy will be useful for the diagnosis, treatment, and prevention of PBZ toxicity. Objectives To identify putative proteins associated with equine gastric ulcer syndrome after clinical dose (4.4 mg/kg ...
Ruethaiwan Vinijkumthorn, Nawarus Prapaiwan, Thanapon Chotikaprakal, Phirom Prompiram, Narumon Phaonakrop, Sittiruk Roytrakul, Parichart Tesena   +6 more
wiley   +1 more source

Figure S2 from Phosphorylated Acetyl-CoA Carboxylase Is Associated with Clinical Benefit with Regorafenib in Relapsed Glioblastoma: REGOMA Trial Biomarker Analysis

, 2023
Stefano Indraccolo, Gian Luca De Salvo, Martina Verza, Mario Caccese, Giovanni Esposito, Ilaria Piga, Paola Del Bianco, Marco Pizzi, Marina Paola Gardiman, Marica Eoli, Roberta Rudà, Alba A. Brandes, Toni Ibrahim, Simona Rizzato, Ivan Lolli, Vittorina Zagonel, Giuseppe Lombardi   +16 more
openalex   +1 more source

From Adipose Tissue to Cardiac Repair: Extracellular Vesicles in Cardiovascular Regeneration

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Adipose‐derived extracellular vesicles (ADEVs) secreted by adipose tissue have gained increasing attention due to their regenerative and immunomodulatory properties in cardiovascular diseases. They carry proteins, lipids, and nucleic acids that mediate intercellular communication and influence cardiac pathophysiology. In atherosclerosis, ADEVs
Karolina Ignaczak, Pola Ochocka, Karol Sadowski, Weronika Ploch, Dominika Tomkiel, Mariusz Tomaniak, Wioletta Olejarz   +6 more
wiley   +1 more source

Dephosphorylation and activation of Acetyl‐CoA‐carboxylase from lactating rabbit mammary gland [PDF]

, 1979
D. Grahame Hardie, Philip Cohen
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Mitochondrial β‐carbonic anhydrase is a conserved metabolic rheostat for branched‐chain amino acid catabolism and metabolic flexibility

New Phytologist, Volume 250, Issue 4, Page 2415-2427, May 2026.
Summary Carbonic anhydrases (CAs) are ubiquitous metalloenzymes that catalyze the reversible hydration of CO2, enabling fundamental processes in organisms across all domains of life. Among all CAs, the role of mitochondrial βCA remains poorly understood. Here, we identify a mitochondrial βCA, βCA6, as a key regulator of branched‐chain amino acid (BCAA)
Naveen Sharma, Thomas D. Sharkey, Federica Brandizzi   +2 more
wiley   +1 more source

Design, synthesis, and structure–activity relationships of novel spiro-piperidines as acetyl-CoA carboxylase inhibitors

, 2012
Makoto Kamata, Tohru Yamashita, Asato Kina, Masaaki Funata, Atsushi Mizukami, Masako Sasaki, Akiyoshi Tani, Miyuki Funami, Nobuyuki Amano, K. Fukatsu   +9 more
openalex   +1 more source

Regulation of eukaryotic acetyl-CoA carboxylases

, 2018
Many biological carboxylation reactions are catalyzed by ubiquitous biotin-dependent carboxylases. Their mechanism involves three conserved functional components; First, a biotin moiety, covalently linked to the biotin carboxyl carrier protein (BCCP) is carboxylated under ATP consumption at the biotin carboxylase (BC). Then the BCCP translocates to the
openaire   +3 more sources

Molecular Targeted Suppression of Male Fertility in Amaranthus palmeri S. Watson: Function and Layered Double Hydroxide Nanosheets‐Based Delivery System of ApmiR319

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3296-3307, May 2026.
ABSTRACT Amaranthus palmeri is one of the most troublesome invasive agricultural weeds worldwide, exhibiting super invasiveness and high resistance to conventional management strategies. Artificial microRNA‐mediated silencing technology, coupled with a nanoparticle‐mediated delivery system, represents an attractive approach for fertility control in A ...
Liyong Sun, Yusen Wang, Minglu Yin, Lina Xu, Yao Chen, Shuxian Li, Zengfang Yin   +6 more
wiley   +1 more source