Results 181 to 190 of about 146,351 (241)

Ferroptosis: Newly Emerged Regulator for Human Disease

MedComm, Volume 7, Issue 9, September 2026.
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao, Lin Ye, Tianqi Jiang, Mengyuan Liu, Yuxia Zhou   +4 more
wiley   +1 more source

Heat Shock Proteins in Cancer: Mechanisms and Therapeutic Targeting

MedComm, Volume 7, Issue 9, September 2026.
This review illustrates heat shock proteins (HSPs) as central regulators of cancer metabolic reprogramming. By stabilizing key metabolic enzymes and coordinating glycolysis, oxidative phosphorylation, redox homeostasis, and stress adaptation, HSPs support tumor growth, metastasis, and therapeutic resistance. Targeting HSP networks may therefore provide
Sheng Ma, Chen‐Qian Liu, Si‐Yang Ma, Shao‐Gang Wang, Qi‐Dong Xia, Meng‐Yao Xu   +5 more
wiley   +1 more source

Lipodystrophy and adipose tissue recovery are mediated by the Wnt/lipogenesis axis during skin fibrosis

The Journal of Pathology, Volume 270, Issue 1, Page 98-113, September 2026.
Abstract Acquired lipodystrophy in the dermal white adipose tissue (DWAT) is an early phenotype of skin fibrosis, followed by the accumulation of extracellular matrix (ECM). Lipodystrophy syndromes are estimated to affect 1 in 20,000 people and are associated with metabolic comorbidities.
Suneeti R Madhavan, Piper Moore, Rohan Varshney, Miles Montegut, Qiannan Ma, Kayla Klatt, Reshmi Parameswaran, Elif G Ertugral, Chandrasekhar R Kothapalli, Michael C Rudolph, Radhika P Atit   +10 more
wiley   +1 more source

Molecular Mechanisms of Food Bioactive Constituents in the Management of Obesity and Hypertension: A Critical Review

Phytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
Obesity and hypertension co‐exist and share molecular mechanisms in terms of dietary therapy, modulated by food bioactive constituents. ABSTRACT Obesity and hypertension are among the most pressing global public health challenges. They frequently co‐exist, with obesity‐related hypertension accounting for an estimated 75% of the hypertension burden ...
Samuel Oluwasegun Maccarthy, Emmanuel Anyachukwu Irondi, Abdulazeez Olamilekan Elemosho, Emmanuel Oladipo Ajani   +3 more
wiley   +1 more source

When Fat Goes Astray: Your Liver and Pancreas Get Into Trouble

Portal Hypertension &Cirrhosis, Volume 5, Issue 3, Page 269-282, September 2026.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) and intrapancreatic fat deposition (IPFD) are both common manifestations of ectopic fat accumulation. Although they share multiple risk factors, they also show notable differences in pathological features, standardization of diagnosis, and research maturity.
Yuying Chen, Li Ding, Shan Zhao, Weihong Wang, Jing Zhong, Qiang Yan   +5 more
wiley   +1 more source

Tributyltin Protumorigenic Effects Targeting Prostate Cancer Cell Metabolism, Proliferation, Migration, and Invasion

Environmental Toxicology, Volume 41, Issue 9, Page 709-729, September 2026.
ABSTRACT Prostate cancer (PCa) is an endocrine‐related cancer highly dependent on androgenic signaling. Beyond hormone dependence, extrinsic factors play a significant role in the risk of developing PCa, which raises concern about the influence of environmental compounds such as endocrine‐disrupting chemicals (EDCs). Tributyltin (TBT) is an EDC used in
Mariana Feijó, Luís P. Brás, Catarina M. D. Serra, Lara R. S. Fonseca, Sara Correia, Bruno J. Pereira, Ana P. Duarte, Henrique J. Cardoso, Cátia V. Vaz, Sílvia Socorro   +9 more
wiley   +1 more source

Harnessing of Tomato (Solanum lycopersicum) Pomace Powder on Growth Response and Haematological Indices of Sonali Chickens

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Dried tomato pomace powder is evaluated as a functional feed additive for Sonali chickens under tropical conditions. Dietary supplementation up to 6% improves growth performance, feed efficiency, carcass yield, serum lipid profile and economic return without adverse haematological effects.
Md. Ahsan Habib, Manish Halder, Ummay Salma, Md. Nurul Amin, Sabbir Hossen Sabuz, Ayesha Siddika, MD. Al Fattah, Ishrat Jahan, Umesh Kumar Yadav   +8 more
wiley   +1 more source

A Review on Heat Stress in Broiler Chickens: Mechanisms, Effects and Mitigation Strategies

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Heat stress caused by high temperature and humidity compromises broiler health, welfare, and productivity by reducing feed intake, growth performance, and feed efficiency, while increasing mortality, oxidative stress, metabolic disturbances, intestinal dysfunction, gut dysbiosis, immune suppression, and meat quality deterioration.
Maksuda Begum, Laura Musa, Guido Grilli, Dilşan Akçay, Md Golam Kibria, Mst. Mayeeda Parvin, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed, Delower Hossain   +8 more
wiley   +1 more source

Brazilian Green Propolis and Essential Oil Residues Improve Metabolic Dysfunction by Modulating Key Hepatic Lipogenic Genes in High‐Fat Diet‐Fed Mice

Journal of Food Science, Volume 91, Issue 9, September 2026.
ABSTRACT Obesity is closely associated with metabolic dysfunction, leading to impaired glucose and lipid homeostasis and contributing to the development of metabolic dysfunction–associated liver disease (MASLD). Propolis is a bee‐derived natural product rich in bioactive compounds and widely recognized for its antioxidant, anti‐inflammatory, and ...
Caroline Alves de Araújo, Giovana Dias Ramundo, Beatriz Teixeira dos Santos, Dafne Lopes Beserra Silva, Graziele Freitas de Bem, Dayane Teixeira Ognibene, Angela Castro Resende, Brenda Akemi Nagagata, Isabela Macedo Lopes Vasques‐Monteiro, Julio Beltrame Daleprane, Debora Baptista Pereira, Douglas Siqueira de Almeida Chaves, Cristiane Aguiar da Costa   +12 more
wiley   +1 more source

Autophagy in MASLD: A Metabolic and Precision Medicine Perspective

Liver International, Volume 46, Issue 9, September 2026.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver condition worldwide and a major contributor to cirrhosis and hepatocellular carcinoma (HCC). While metabolic triggers such as obesity and insulin resistance are key drivers of MASLD, growing evidence has identified defects in intracellular quality
Alessandra Cazzaniga, Silvia Frigo, Alessandro Cherubini, Eniada Rrapaj, Luca Valenti   +4 more
wiley   +1 more source