Results 211 to 220 of about 86,728 (368)

Pharmacological induction of acetyl-CoA carboxylase 1 autophagic degradation attenuates lipid accumulation and cholangiocarcinoma progression. [PDF]

open access: yesJ Exp Clin Cancer Res
Pan Y   +13 more
europepmc   +1 more source

Interaction Between Photoperiod and Sex on Hepatic Lipid Homeostasis in Rats Fed an Obesogenic Diet

open access: yesThe FASEB Journal, Volume 39, Issue 23, 15 December 2025.
Male and female Fischer 344 rats were fed a cafeteria (CAF) diet for 11 weeks and exposed to long (L18, 18 h of light per day) or short (L6, 6 h of light per day) photoperiods for 8 weeks. Photoperiod and sex influenced hepatic steatosis, plasmatic and hepatic lipid levels, and hepatic lipid handling, showing sex‐specific metabolic responses to ...
Saioa Gómez‐Roncal   +6 more
wiley   +1 more source

Suppressing Glycerol‐3‐phosphate Phosphatase and Enhancing Glycerol‐3‐Phosphate Shuttle Flux Crucial for High‐Efficiency Fatty Acid Production in the Fast‐Growing Oleaginous Schizochytrium

open access: yesAdvanced Science, Volume 12, Issue 45, December 4, 2025.
This study establishes an efficient oleaginous heterotrophic microalga, Schizochytrium, through chassis optimization and metabolic engineering, significantly enhancing fatty acid titers and productivities. It also identifies a regulatory mechanism that coordinates biomass and lipid synthesis, providing a rational target for metabolic pathway rewiring ...
Fangzhong Wang   +7 more
wiley   +1 more source

Inhibition of acetyl-CoA carboxylase impaired tubulin palmitoylation and induced spindle abnormalities. [PDF]

open access: yesCell Death Discov, 2023
Fang CT   +6 more
europepmc   +1 more source

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