Interaction of acetyl‐CoA fragments with rat liver acetyl‐CoA carboxylase [PDF]
European Journal of Biochemistry, 1990 The interaction of acetyl‐CoA fragments with rat liver acetyl‐CoA carboxylase has been studied. Dephosphorylated acetyl‐CoA did not actually differ from acetyl‐CoA in its substrate properties. Non‐nucleotide analogues of the substrate, S‐acetylpantatheine and it's 4′‐phosphate, also possess substrate properties (Vmax= 1.5% and 15% of the maximal rate ...
A G, Rabinkov +4 more
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Programmed cell death in pathogenesis induced by herbicides inhibitors of acetyl-CoA-carboxylase
Біологічні студії, 2013 Importance of pathogenesis induced by herbicides whose phytotoxic action is caused by the interaction with photosynthesis is discussed. For this class of herbicides, the participation of programmed cell death and the role of reactive oxygen species (ROS)
A. M. Sychuk +2 more
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Molecular Basis for Resistance to Fluazifop-P-Butyl in Itchgrass (Rottboellia cochinchinensis) from Costa Rica [PDF]
Planta Daninha, 2016 Rottboellia cochinchinensis is an annual grass weed species known as itchgrass, or "caminadora" in America´s Spanish speaking countries, and has become a major and troublesome weed in several crops.
R. CASTILLO-MATAMOROS +3 more
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Molecular regulation of the cardiac-enriched acetyl-CoA carboxylase isoform (ACCβ) : a novel target for therapeutic interventions in cardiovascular disease [PDF]
, 2006 Includes bibliographical references (leaves 130-173).Metabolic remodeling is thought to be an important contributor towards the development of various cardiac pathophysiologic conditions.
Makaula, Siyanda S S
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Studies on the Intracellular Localization of Acetyl-CoA Carboxylase [PDF]
Biochemical and Biophysical Research Communications, 1997 The present work was performed to identify the subcellular localization of hepatic acetyl-CoA carboxylase (ACC). Cellular organelles involved in fatty acid oxidation that contain a malonyl-CoA sensitive carnitine palmitoyltransferase (CPT) activity or that are linked to the control of this activity were analysed for the presence of ACC.
Geelen, M.J.H. +4 more
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Fine-tuning acetyl-CoA carboxylase 1 activity through localization: functional genomics reveals a role for the lysine acetyltransferase NuA4 and sphingolipid metabolism in regulating Acc1 activity and localization [PDF]
, 2022 Acetyl-CoA Carboxylase 1 catalyzes the conversion of acetyl-CoA to malonyl-CoA, the committed step of de novo fatty acid synthesis. As a master regulator of lipid synthesis, acetyl-CoA carboxylase 1 has been proposed to be a therapeutic target for ...
Fullerton, Morgan D +10 more
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Inhibition of rat liver acetyl CoA carboxylase by chloride
Journal of Lipid Research, 1980 The activity of acetyl CoA carboxylase in both crude and purified rat liver preparations was reduced in the presence of sodium or potassium chloride and increased in the presence of potassium acetate.
J B Allred, K L Roehrig
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The source of malonyl-CoA in rat heart The calcium paradox releases acetyl-CoA carboxylase and not propionyl-CoA carboxylase [PDF]
, 1986 The formation of malonyl-CoA in rat heart is catalyzed by cytosolic acetyl-CoA carboxylase. The existence of this enzyme in heart is difficult to prove by the abundant occurrence of mitochondrial propionyl-CoA carboxylase, which is also able to catalyze ...
Dubelaar, Marie-Louise +7 more
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Journal of Lipid Research, 2003 Hamsters were fed a control diet or diets containing palm, olive, safflower, or fish oil for 2 weeks. In villus cell populations from duodenum, jejunum, and ileum, rates of intestinal fatty acid and cholesterol synthesis were estimated, as were sterol ...
F. Jeffrey Field +2 more
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Nature Communications, 2022 Here the authors report that inhibition of de novo fatty acid synthesis by deleting the enzyme Acetyl-CoA-Carboxylase 1 in the intestinal epithelium results in the loss of crypt structures and a specific decline in Lgr5+ intestinal epithelial stem cells.
Shuting Li +14 more
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