Results 51 to 60 of about 42,990 (270)

The source of malonyl-CoA in rat heart The calcium paradox releases acetyl-CoA carboxylase and not propionyl-CoA carboxylase

open access: yes, 1986
The formation of malonyl-CoA in rat heart is catalyzed by cytosolic acetyl-CoA carboxylase. The existence of this enzyme in heart is difficult to prove by the abundant occurrence of mitochondrial propionyl-CoA carboxylase, which is also able to catalyze ...
Dubelaar, Marie-Louise   +7 more
core   +1 more source

Hepatic zonation of acetyl-CoA carboxylase activity [PDF]

open access: yesBiochemical Journal, 1990
The activities of several hepatic enzymes are preferentially zonated to the periportal or perivenous cells of the liver acinus. Employing dual-digitonin-pulse perfusion of rat liver in the study of acetyl-CoA carboxylase (ACC), we have identified a heretofore unrecognized feature of hepatic zonation, namely an intrahepatic gradient in enzyme specific ...
Quistorff, Bjørn   +2 more
openaire   +3 more sources

MicroRNA‐Seq Analysis Reveals a Critical Role for miR‐222 in Bovine Intramuscular Adipogenesis via the DDIT4/mTORC1 Axis

open access: yesAnimal Research and One Health, EarlyView.
Schematic diagram illustrating how miR‐222 promotes bovine intramuscular adipogenesis by targeting DDIT4 to activate the mTORC1 signaling pathway. ABSTRACT Intramuscular fat (IMF) is a key determinant of beef quality, particularly with respect to tenderness, flavor, and juiciness.
Jianbing Tan   +7 more
wiley   +1 more source

Diet-induced obesity impairs mammary development and lactogenesis in murine mammary gland

open access: yes, 2005
We have developed a mouse model of diet-induced obesity that shows numerous abnormalities relating to mammary gland function. Animals ate 40% more calories when offered a high-fat diet and gained weight at three times the rate of controls. They exhibited
Kelly, Paul A.   +9 more
core   +1 more source

A Novel β/ε Subunit Combination Expands the Tri-Subunit Acyl-CoA Carboxylase Repertoire in Streptomyces coelicolor

open access: yesMicroorganisms
Acyl-CoA carboxylase (YCC) complexes generate essential starter and extender units for fatty acid and polyketide biosynthesis in Actinobacteria. In Streptomyces coelicolor, two tri-subunit YCC complexes, acetyl-CoA carboxylase (ACC) and propionyl-CoA ...
Shiyu Wu   +8 more
doaj   +1 more source

Acetyl CoA Carboxylase: The Purified Transcarboxylase Component [PDF]

open access: yesProceedings of the National Academy of Sciences, 1971
Acetyl CoA carboxylase of Escherichia coli has been resolved into three functionally dissimilar proteins: ( 1 ) biotin-carboxyl carrier protein (BCCP); ( 2 ) a biotin carboxylase component that catalyzes the Mn-ATP-dependent carboxylation of BCCP to form CO
A W, Alberts, S G, Gordon, P R, Vagelos
openaire   +2 more sources

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

open access: yesAnimal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar   +8 more
wiley   +1 more source

De novo synthesis and elongation of fatty acids by subcellular fractions of monkey aorta

open access: yesJournal of Lipid Research, 1968
Subcellular fractions of aorta of squirrel monkey (Saimiri sciureus) were examined for their ability to synthesize and elongate fatty acids. High-speed supernate (HSS) incorporated substantial quantities of malonyl CoA into fatty acids while acetyl CoA ...
Charles F. Howard, Jr.
doaj   +1 more source

Pyrrolocin C and equisetin inhibit bacterial acetyl-CoA carboxylase.

open access: yesPLoS ONE, 2020
Antimicrobial resistance is a growing global health and economic concern. Current antimicrobial agents are becoming less effective against common bacterial infections.
Erica C Larson   +7 more
doaj   +1 more source

Indole‐3‐Acetic Acid Protects Bovine Hepatocytes Against Palmitic Acid‐Induced Lipid Accumulation and ER Stress Through SIRT3

open access: yesAnimal Research and One Health, EarlyView.
Cows with ketosis during the perinatal period often experience damage to the liver, a core metabolic organ, thereby exacerbating the disease's inherent vicious cycle. This study indicates that serum 3‐IAA concentrations were reduced in ketotic cows and show a significant negative correlation with hepatic TG content.
Dandan Qi   +15 more
wiley   +1 more source

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