Results 51 to 60 of about 43,087 (252)
Structural basis for regulation of human acetyl-CoA carboxylase [PDF]
, 2018 Acetyl-CoA carboxylase catalyses the ATP-dependent carboxylation of acetyl-CoA, a rate-limiting step in fatty acid biosynthesis(1,2). Eukaryotic acetyl-CoA carboxylases are large, homodimeric multienzymes.
Hagmann, Anna +6 more
core +3 more sources
ACETYL-COA-CARBOXYLASE ACTIVITY IN NORMALLY DEVELOPING WHEAT LEAVES [PDF]
, 1987 ACETYL-COA-CARBOXYLASE ACTIVITY IN NORMALLY DEVELOPING WHEAT ...
JC HAWKE (17322886), RM LEECH (18713899)
core +2 more sources
Inhibition of rat liver acetyl CoA carboxylase by chloride
Journal of Lipid Research, 1980 The activity of acetyl CoA carboxylase in both crude and purified rat liver preparations was reduced in the presence of sodium or potassium chloride and increased in the presence of potassium acetate.
J B Allred, K L Roehrig
doaj +1 more source
Fatty acids and their metabolism critically regulate podocyte survival [PDF]
, 2014 Diabetic nephropathy (DN) is the most common cause of end-stage renal disease in industrialized countries, and most affected patients have type 2 diabetes.
Kampe, Kapil Dev
core +1 more source
Journal of Lipid Research, 2003 Hamsters were fed a control diet or diets containing palm, olive, safflower, or fish oil for 2 weeks. In villus cell populations from duodenum, jejunum, and ileum, rates of intestinal fatty acid and cholesterol synthesis were estimated, as were sterol ...
F. Jeffrey Field +2 more
doaj +1 more source
A Biotin Analog Inhibits Acetyl-CoA Carboxylase Activity and Adipogenesis [PDF]
, 2002 Acetyl-CoA carboxylase catalyzes the first committed step in the synthesis of long chain fatty acids. In this study, we observed that treatment of 3T3-L1 cells with biotin chloroacetylated at the 1\u27 nitrogen reduced the enzymatic activity of cytosolic
Jacqueline M. Stephens +5 more
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Expression of genes encoding acetyl-CoA carboxylase, biotin synthase, and acetyl-CoA generating enzymes in Arabidopsis thaliana [PDF]
, 1997 Acetyl-CoA carboxylase catalyzes the formation of malonyl-CoA from acetyl-CoA. The four genes encoding heteromeric acetyl-CoA carboxylase are coordinately expressed in leaves, flowers, and developing siliques and embryos. The highest expression occurs in
Ke, Jinshan
core +1 more source
Nature Communications, 2022 Here the authors report that inhibition of de novo fatty acid synthesis by deleting the enzyme Acetyl-CoA-Carboxylase 1 in the intestinal epithelium results in the loss of crypt structures and a specific decline in Lgr5+ intestinal epithelial stem cells.
Shuting Li +14 more
doaj +1 more source
Hepatic zonation of acetyl-CoA carboxylase activity [PDF]
Biochemical Journal, 1990 The activities of several hepatic enzymes are preferentially zonated to the periportal or perivenous cells of the liver acinus. Employing dual-digitonin-pulse perfusion of rat liver in the study of acetyl-CoA carboxylase (ACC), we have identified a heretofore unrecognized feature of hepatic zonation, namely an intrahepatic gradient in enzyme specific ...
Quistorff, Bjørn +2 more
openaire +3 more sources
Purification and characterisation of an insulin-stimulated protein-serine kinase which phosphorylates acetyl-CoA carboxylase [PDF]
, 1998 An insulin-stimulated protein kinase specific for acetyl-CoA carboxylase has been purified from rat epididymal adipose tissue using Mono-Q chromatography.
Moule, S.K +8 more
core +1 more source