Results 61 to 70 of about 42,990 (270)
Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy
BMEMat, EarlyView.Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu +5 more
wiley +1 more source
Frontiers in Microbiology, 2016 The family of PII signal transduction proteins (members GlnB, GlnK, NifI) plays key roles in various cellular processes related to nitrogen metabolism at different functional levels.
Waldemar Hauf +5 more
doaj +1 more source
The polymerization of acetyl-CoA carboxylase.
Journal of Biological Chemistry, 1983 Citrate, an allosteric activator of acetyl-CoA carboxylase, induces polymerization of an inactive protomeric form of the enzyme into an active filamentous form composed of 10-20 protomers. The light-scattering properties of the carboxylase were used to study the kinetics of its polymerization and depolymerization.
N B, Beaty, M D, Lane
openaire +2 more sources
Cloning of human acetyl‐CoA carboxylase cDNA [PDF]
European Journal of Biochemistry, 1994 Acetyl‐CoA carboxylase is the rate‐limiting enzyme in the biogenesis of long‐chain fatty acids. In order to understand the mechanisms that regulate human acetyl‐CoA carboxylase at the gene level, and the relationship between its structure and function, cDNA clones for human acetyl‐CoA carboxylase have been isolated and sequenced.
J, Ha +5 more
openaire +2 more sources
The Distinctive Regulatory Mechanisms of Bacterial Acetyl-CoA Carboxylase
, 2018 Metabolic Regulation is a complex system used to control cellular metabolism in response to conditions in the cell’s environment. For most enzymes, the cell can rely upon a minimal amount of regulation; however, critical enzymes, such as acetyl-CoA ...
Evans, Alexandra Leigh
core +1 more source
Structural basis for regulation of human acetyl-CoA carboxylase
, 2018 Acetyl-CoA carboxylase catalyses the ATP-dependent carboxylation of acetyl-CoA, a rate-limiting step in fatty acid biosynthesis(1,2). Eukaryotic acetyl-CoA carboxylases are large, homodimeric multienzymes.
Hagmann, Anna +6 more
core +2 more sources
ACETYL-COA-CARBOXYLASE ACTIVITY IN NORMALLY DEVELOPING WHEAT LEAVES
, 1987 ACETYL-COA-CARBOXYLASE ACTIVITY IN NORMALLY DEVELOPING WHEAT ...
JC HAWKE (17322886), RM LEECH (18713899)
core +1 more source
Phosphorylation of pea chloroplast acetyl‐CoA carboxylase [PDF]
The Plant Journal, 1999 SummaryWe have examined whether chloroplast acetyl‐CoA carboxylase is a phosphoprotein. Pea (Pisum sativum) chloroplasts were incubated in the presence of [γ‐33P]‐ATP and radiolabeled proteins were examined after immunoprecipitation with antibodies against all four known subunits of heteromeric chloroplast acetyl‐CoA carboxylase.
, Savage, , Ohlrogge
openaire +2 more sources
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Sequences of acetyl CoA carboxylase promoter for tumour necrosis factor action
Mediators of Inflammation, 1993 Tumour necrosis factor (TNF) inhibits the accumulation of acetyl CoA carboxylase (ACC) mRNA by decreasing the rate of ACC gene transcription. The ACC mRNA species found in 30A5 cells are generated from promoter II and TNF inhibits the accumulation of ...
Keerang Park +2 more
doaj +1 more source