Results 21 to 30 of about 396 (171)
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease
Hepatology, EarlyView., 2022 RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso +16 more
wiley +1 more source
Studying the Protective Effect of N-acetyl cysteine and Lcarnitine on Testicular Toxicity Induced by Valproic Acid Administration in Adult Male Albino Rats [PDF]
Ain Shams Journal of Forensic Medicine and Clinical Toxicology, 2023 Introduction: Sodium valproate (VPA) is a well-known antiepileptic drug used in treatment of generalized seizures and cause many toxic effects. Aim: This study aimed to highlight the VPA effects on testes in adult male albino rats and protective effect ...
Ahmed Said +5 more
doaj +1 more source
Acetyl-L-Carnitine in Parkinson’s Disease [PDF]
, 2012 Parkinson’s disease (PD) is the most common neurodegenerative movement disorder that is estimated to affect approximately 1% of the population older than 65 years of age (deRijk et al., 2006; Saunders, 2000). PD was first described in 1818 by the British physician J. Parkinson.
SINICROPI, Maria Stefania +3 more
openaire +2 more sources
Metabolites, 2021 The diabetic heart is energetically and metabolically abnormal, with increased fatty acid oxidation and decreased glucose oxidation. One factor contributing to the metabolic dysfunction in diabetes may be abnormal handling of acetyl and acyl groups by ...
Dragana Savic +9 more
doaj +1 more source
Acetyl-L-carnitine flux to lipids in cells estimated using isotopomer spectral analysis
Journal of Lipid Research, 1997 Acetyl-L-carnitine is known as a reservoir of activated acetyl units and as a modulator of metabolic function. The objective of this study was to quantify the fate of the acetyl moiety of acetyl-L-carnitine in lipogenic pathways.
L Lligona-Trulla +4 more
doaj +1 more source
Reproductive and Developmental Medicine, 2020 Objective: To investigate the relationship between the concentration of L-carnitine in semen and sperm parameters and investigate the epigenetic profile in sperm cell after L-carnitine usage. Methods: From February 2017 to February 2018, 46 semen samples
Xiao-Hui Jiang +7 more
doaj +1 more source
Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer's Dementia.
PLoS ONE, 2016 This study aimed to determine the serum levels of free L-carnitine, acetyl-L-carnitine and 34 acyl-L-carnitine in healthy subjects and in patients with or at risk of Alzheimer's disease.
Adriana Cristofano +10 more
doaj +1 more source
l-carnitine, a friend or foe for cardiovascular disease? A Mendelian randomization study
BMC Medicine, 2022 Background l-carnitine is emerging as an item of interest for cardiovascular disease (CVD) prevention and treatment, but controversy exists. To examine the effectiveness and safety of l-carnitine, we assessed how genetically different levels of l ...
Jie V. Zhao +3 more
doaj +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
L-carnitine use as a trigger for the onset of Kleine-Levin syndrome: A case presentation (eng)
Klinik Psikiyatri Dergisi, 2022 Kleine- Levin Syndrome (KLS) is a rare phenomenon characterized by repeating episodes of hypersomnia, cognitive and behavioral impairments, compulsive eating behavior, and hypersexuality.
Ferhat Yaylaci +2 more
doaj +1 more source