Results 41 to 50 of about 396 (171)
Effects of L-carnitine and L-acetyl-carnitine on testicular sperm motility and chromatin quality [PDF]
Iranian Journal of Reproductive Medicine, 2012 Background: Sperm cells extracted from testes (TESE) have poor chromatin quality and motility. Various substances are used in the laboratory to increase sperm motility and improve the ART outcomes; however, there are few research which considered ...
Elham Aliabadi +5 more
doaj
Role of Carnitine in Non-alcoholic Fatty Liver Disease and Other Related Diseases: An Update
Frontiers in Medicine, 2021 Carnitine is an amino acid-derived substance that coordinates a wide range of biological processes. Such functions include transport of long-chain fatty acids from the cytoplasm to the mitochondrial matrix, regulation of acetyl-CoA/CoA, control of inter ...
Na Li, Na Li, Hui Zhao
doaj +1 more source
TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis
Advanced Science, EarlyView.A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu +12 more
wiley +1 more source
Open Veterinary JournalBackground: This study was conducted to investigate the biochemical impact of acetyl-L-carnitine (350 mg/ewe) administration with or without Selenium-fortified Saccharomyces cerevisiae (0.03 mg/kg body weight) on 24 mature ewes for 60 days.
Sarmad Talib Abdulazeez +1 more
doaj +1 more source
Scientific Reports, 2021 To understand the characteristic of changes of serum metabolites between healthy people and patients with hepatitis B virus (HBV) infection at different stages of disease, and to provide reference metabolomics information for clinical diagnosis of liver ...
Hui Li +5 more
doaj +1 more source
The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence
AgriFood: Journal of Agricultural Products for Food, EarlyView.Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John +4 more
wiley +1 more source
Acetyl-l-Carnitine in the Treatment of Peripheral Neuropathies: A Narrative Review
Pain and TherapyAcetyl-l-carnitine is an ester of l-carnitine, both endogenous molecules, with a vital role in lipid metabolism. Exogenously delivered acetyl-l-carnitine is endowed with neuroprotective and neurotrophic actions due to its antioxidant and metabolic ...
Diego Maria Michele Fornasari
doaj +1 more source
Biomedicines, 2023 Carnitines play a key physiological role in oocyte metabolism and redox homeostasis. In clinical and animal studies, carnitine administration alleviated metabolic and reproductive dysfunction associated with polycystic ovarian syndrome (PCOS).
Martina Placidi +10 more
doaj +1 more source
Animal Research and One Health, EarlyView.Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar +8 more
wiley +1 more source
OCTN2-Mediated Acetyl-l-Carnitine Transport in Human Pulmonary Epithelial Cells In Vitro
Pharmaceutics, 2019 The carnitine transporter OCTN2 is associated with asthma and other inflammatory diseases. The aims of this work were (i) to determine carnitine uptake into freshly isolated human alveolar type I (ATI)-like epithelial cells in primary culture, (ii) to ...
Johanna J. Salomon +7 more
doaj +1 more source