Results 241 to 250 of about 49,331 (295)

Mechanism of metamifop inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in Echinochloa crus-galli. [PDF]

Sci Rep, 2016
Xia X, Tang W, He S, Kang J, Ma H, Li J.
europepmc   +1 more source

Ovarian Aging: A Multifaceted Perspective on Mechanisms

Cell Proliferation, Volume 59, Issue 1, January 2026.
A mechanistic network of ovarian aging, highlighting mitochondrial dysfunction as a central hub interconnected with genetic, metabolic, and inflammatory pathways.
Xiaoqing Zhang, Xinyi Dong, Xue Zhang, Suying Yuan, Qiran Zhang, Zilu Guo, Xiaoxue Yang, Qionghua Wang, Tianlan Yang, Donghui Huang   +9 more
wiley   +1 more source

Structural characterisation of nucleotide sugar short‐chain dehydrogenases/reductases from the thermophilic pseudomurein‐containing methanogen Methanothermobacter thermautotrophicus ΔH

The FEBS Journal, Volume 293, Issue 2, Page 492-513, January 2026.
Nucleotide sugar short‐chain dehydrogenases/reductases (NS‐SDRs) are involved in pseudomurein and capsular polysaccharide formation in methanogenic Archaea. Methanothermobacter thermautotrophicus possesses several NS‐SDRs labelled Mth375, Mth380, Mth373, Mth631 and Mth1789.
Vincenzo Carbone, Linley R. Schofield, Patrick J. B. Edwards, Andrew J. Sutherland‐Smith, Ron S. Ronimus   +4 more
wiley   +1 more source

Convergent Metabolic Pathways in MASH Therapeutics: An AMPK‐Centric Analysis

Journal of Cellular and Molecular Medicine, Volume 30, Issue 2, January 2026.
ABSTRACT Metabolic dysfunction‐associated steatohepatitis (MASH) is a leading cause of liver‐related morbidity driven by systemic metabolic dysregulation. The recent approval of resmetirom and the clinical success of GLP‐1 receptor agonists have heralded a new era in MASH therapy, yet a convergent understanding of the complex mechanisms of these ...
Seungchan Choi, Jin‐Seok Jung, Yie‐sung Seo, Sungmin Song, Jeehye Ham, Hannah Chung, Yousef Ramadan, Kangchan Choi   +7 more
wiley   +1 more source

Bioenergetic profiles and respiratory control in mitochondrial physiology: Precision analysis of oxidative phosphorylation

Experimental Physiology, Volume 111, Issue 1, Page 179-211, 1 January 2026.
Abstract Oxidative phosphorylation (OXPHOS) is fundamental to mitochondrial function. Respirometry with living cells provides limited information compared to precision OXPHOS analysis with mitochondrial preparations, including isolated mitochondria, tissue homogenates, permeabilized tissues, and permeabilized cells.
Alba Timón‐Gómez, Carolina Doerrier, Zuzana Sumbalová, Luiz F. Garcia‐Souza, Eleonora Baglivo, Luiza H. D. Cardoso, Erich Gnaiger   +6 more
wiley   +1 more source

Dietary nitrate supplementation mitigates age‐related changes at the neuromuscular junction in mice

The Journal of Physiology, Volume 604, Issue 2, Page 886-916, 15 January 2026.
Abstract figure legend Ageing is associated with a decline in muscle mass and strength, namely sarcopenia, significantly impacting the quality of life in older individuals. Different strategies are being explored to counteract these detrimental effects. In the present study, we investigated a non‐invasive nutritional approach: the impact of 2 months of
Maira Rossi, Lucrezia Zuccarelli, Lorenza Brocca, Cristiana Sazzi, Clarissa Gissi, Paola Rossi, Bruno Grassi, Simone Porcelli, Roberto Bottinelli, Maria Antonietta Pellegrino   +9 more
wiley   +1 more source

Leaf Ethanol Extract of Dimocarpus longan Lour. Ameliorates Type 2 Diabetes Mellitus in Rats by Regulating Metabolic Pathways and Gut Microbiota

Biochemistry Research International, Volume 2026, Issue 1, 2026.
Background The leaves of Dimocarpus longan Lour. are used unilaterally as Chinese herbal medicines to treat diabetes in Chongzuo and Hezhou, Guangxi, but the mechanism of its treatment of diabetes is not yet clear, and further research is needed. Methods This study examined the effects of leaf ethanol extract of D.s longan Lour.
Chunlian Lu, Piaoxue Zheng, Sisi Chen, Yanli Liang, Yuxin Jiang, Anqi Huo, Jingjing Xie, Jiawen Peng, Yuming Ma, Jiali Wei, Zhidong Ma, Hua Zhu, Jie Liang, Luis C. N. Da Silva   +13 more
wiley   +1 more source

Bidirectional Regulation of NLRP3 Inflammasome and Mitochondrial Quality Control in Sepsis: Mechanisms and Therapeutic Implications

Mediators of Inflammation, Volume 2026, Issue 1, 2026.
Characterized by its capacity to induce organ failure, sepsis constitutes a life‐threatening pathological state with high incidence and mortality rates. Current treatments primarily focus on antimicrobial therapy and organ support, lacking direct interventions targeting the restoration of cellular or organelle function.
Xiangxin Liao, Yixun Wang, Zhaohui Zhang, Xingguang Qu, Gaosheng Zhou, Laurent L′homme   +5 more
wiley   +1 more source

Effects of endurance training on skeletal muscle mitochondrial respiration in Siberian huskies and Alaskan huskies

Physiological Reports, Volume 14, Issue 2, January 2026.
Abstract Siberian huskies (SH) and Alaskan huskies (AH), sharing ancestry with ancient sled dogs, were hypothesized to achieve similar skeletal muscle (SM) mitochondrial respiration capacities and densities through endurance training. High‐resolution respirometry of SM biopsies from SH and AH during off‐season (5 SH, 4 AH) and racing‐season (5 SH, 7 AH)
Silje Sælen‐Helgesson, Anne Dragøy Hafstad, Trine Lund, Ingebjørg Helena Nymo, Chiara Ciccone, Shona Hiedi Wood, Lars P. Folkow, Monica Alterskjær Sundset   +7 more
wiley   +1 more source

Biomimetic sulfur-catalyzed carbonyl transfer enables the carbonylative difunctionalization of unactivated alkenes. [PDF]

Chem Sci
Wang Y, Wu XF.
europepmc   +1 more source