Histone acetylation dynamics regulating plant development and stress responses
Cellular and Molecular Life Sciences, 2021 Verandra Kumar, J. Thakur, M. Prasad
semanticscholar +1 more source
Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress
Nature Communications, 2019 Autophagy receptor p62/SQSTM1 promotes the assembly and removal of ubiquitylated proteins by forming p62 bodies and mediating their encapsulation in autophagosomes.
Zhiyuan You +11 more
semanticscholar +1 more source
Colon‐Targeted Natural Polysaccharide‐Berberine Armored Hydrogel for the Treatment of Colitis
Advanced Healthcare Materials, EarlyView.In this research, a novel hydrogel system targeting the colon is developed, incorporating Rhubarb polysaccharides and berberine‐loaded dendrimer. This hydrogel, forms through intermolecular hydrogen bonding and electrostatic interactions, accumulates in colonic tissues, effectively alleviating pathological immune hyperactivation while modulating gut ...
Miao Guo +8 more
wiley +1 more source
The formation of mercapturic acids. 3. N-Acetylation of S-substituted cysteines in the rabbit, rat and guinea pig [PDF]
, 1959 H. G. Bray +2 more
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Histone Acetylation Promotes Neutrophil Extracellular Trap Formation
Biomolecules, 2019 Neutrophils undergo a unique form of cell death to generate neutrophil extracellular traps (NETs). It is well established that citrullination of histones (e.g., CitH3) facilitates chromatin decondensation during NET formation (NETosis), particularly ...
Hussein J Hamam, M. Khan, N. Palaniyar
semanticscholar +1 more source
Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis
Advanced Healthcare Materials, EarlyView.This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han +7 more
wiley +1 more source
Acetylation of Holocellulose in Fibrous State [PDF]
, 1955 Toshikazu Fujimura
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Epigenetic Chromatin Silencing: Bistability and Front Propagation
, 2007 The role of post-translational modification of histones in eukaryotic gene regulation is well recognized. Epigenetic silencing of genes via heritable chromatin modifications plays a major role in cell fate specification in higher organisms.
Alberts B +13 more
core +1 more source
Circulation Research, 2019 Rationale: SERCA2a, sarco-endoplasmic reticulum Ca2+-ATPase, is a critical determinant of cardiac function. Reduced level and activity of SERCA2a are major features of heart failure.
Przemek A. Gorski +21 more
semanticscholar +1 more source
Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response
Advanced Healthcare Materials, EarlyView.In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim +11 more
wiley +1 more source