Results 201 to 210 of about 374,029 (398)
A K, Balls, F L, Aldrich
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MeCP2 lactylation protects against ischemic stroke by reducing brain infarct volume and improving neurological outcomes. Lactylation at K210/K249 exerts neuroprotective effects by repressing the transcription of apoptosis‐associated genes, including Pdcd4 and Pla2g6. HDAC3 and p300 serve as key regulatory enzymes for MeCP2 lactylation following stroke.
Min Sun+13 more
wiley +1 more source
ON THE ACETYLATION OF ALIPHATIC AMINES BY KIDNEY PREPARATIONS
Marie B. Phillips, H.S. Anker
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The Chemistry Jute-lignin. Part IX. Acetylation of Lignin. [PDF]
PULIN BEHARI SARKAR
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Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain
W. Gu, R. Roeder
semanticscholar +1 more source
Diallyl trisulfides (DATs) selectively induce cuproptosis in hepatic stellate cells (HSCs) by targeting Ras‐related protein Rab‐18 (RAB18) and regulating lipophagy. DATs promote RAB18 phase separation, enhance mitochondrial‐associated membrane structures (MAMs) formation, and increase succinylation of dihydrolipoamide dehydrogenase (DLD) at K320.
Haoyuan Tian+16 more
wiley +1 more source
Confined Migration Drives Stem Cell Differentiation
Human mesenchymal stem cell (hMSC) homing to sites of regeneration requires navigation through mechanically confining extracellular matrix environments, inducing rapid and dramatic morphological adaptation. By exposing hMSCs to specific levels of physiological confinement, it is demonstrated that confinement can induce osteogenesis, and that this fate ...
Xu Gao+6 more
wiley +1 more source
High Sugar Induced RCC2 Lactylation Drives Breast Cancer Tumorigenicity Through Upregulating MAD2L1
This study finds that KAT2A mediates the lactylation modification of the non‐histone protein RCC2 at K124, facilitating the recruitment of free SERBP1 and aiding in the formation of the initial SERBP1‐MAD2L1 complex. SERBP1 enhances the stability of MAD2L1 mRNA and promotes cellular proliferation.
Bowen Zheng+11 more
wiley +1 more source