Results 211 to 220 of about 191,770 (239)
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Nonenzymic acetylation of histones with acetyl phosphate and acetyl adenylate
Biochemistry, 1975Nonenzymatic acetylation of calf-thymus lysine- and arginine-rich histones was demonstrated to occur when these proteins were incubated with [14C]acetyl phosphate and [14C]acetyl adenylate. The levels of acetylation depend on both pH and on reagent concentration.
RAMPONI, GIAMPIETRO +2 more
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Clonazepam acetylation in fast and slow acetylators
Clinical Pharmacology and Therapeutics, 1981Six slow acetylators (SAs) and six rapid acetylators (RAs), as determined by sulfamethazine (SMZ) phenotyping, were each given a 2-mg oral dose of clonazepam. Ninety-six-hour urine collections from these subjects were analyzed for clonazepam, 7-amino clonazepam (7-AM, clonazepam nitroreduced metabolite), and 7-acetamido clonazepam (7-ACT, N-acetylated ...
Miller, Marvin E. +5 more
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Nonenzymatic acetylation of histones with acetyl-CoA
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1970Abstract 1. When purified calf thymus histones were incubated with [1-14C]acetyl-CoA and treated to remove the acid-soluble fraction with trichloroacetic acid, a large amount of radioactivity still remained in the 15 % trichloroacetic acid-insoluble precipitate. 2.
W K, Paik, D, Pearson, H W, Lee, S, Kim
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International Journal of Toxicology, 2023
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 2002, along with updated information regarding product types and concentrations of use, and confirmed that Acetyl Triethyl Citrate, Acetyl Tributyl Citrate, Acetyl Triethylhexyl Citrate, and Acetyl Trihexyl Citrate are safe as cosmetic ...
Wilbur, Johnson +11 more
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The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 2002, along with updated information regarding product types and concentrations of use, and confirmed that Acetyl Triethyl Citrate, Acetyl Tributyl Citrate, Acetyl Triethylhexyl Citrate, and Acetyl Trihexyl Citrate are safe as cosmetic ...
Wilbur, Johnson +11 more
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Acetylation of nucleosides and acetyl migration
Tetrahedron, 1968Abstract Acetylation of the 2′-OH group predominances over acetylation of the 3′-OH group in derivatives of adenosine, uridine, 3β- d -xylosyluracil and 3β- d -lyxosyluracil. In each case subsequent equilibrium of the products of acetylation results in a net acetyl migration away from the glycosidic link.
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Life Sciences, 1981
Abstract Myocardial histone acetylation was investigated in an isolated perfused heart preparation. Radioactive acetate rapidly accumulated in the intracellular compartment which preceded the covalent modification of histones. The acetylation of nucleohistones was rapid and reached a maximum during the first 20 min of perfusion.
P B, Taylor, E A, Cook
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Abstract Myocardial histone acetylation was investigated in an isolated perfused heart preparation. Radioactive acetate rapidly accumulated in the intracellular compartment which preceded the covalent modification of histones. The acetylation of nucleohistones was rapid and reached a maximum during the first 20 min of perfusion.
P B, Taylor, E A, Cook
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Birth defects original article series, 1990
The human acetylation polymorphism has been known for more than three decades since its discovery during the metabolic investigation of the antituberculous hydrazine drug, isoniazid. The trait was originally known as the "isoniazid acetylation polymorphism" but is now usually abbreviated to the "acetylation polymorphism" because the acetylation of ...
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The human acetylation polymorphism has been known for more than three decades since its discovery during the metabolic investigation of the antituberculous hydrazine drug, isoniazid. The trait was originally known as the "isoniazid acetylation polymorphism" but is now usually abbreviated to the "acetylation polymorphism" because the acetylation of ...
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Psychopharmacology, 1979
Microsome-free preparations of rodent and human liver were shown to contain N-acetyl transferase from experiments using procainamide as substrate. These preparations then acetylated phenelzine from the quantitative transfer of radiolabeled acetate. This in vitro demonstration of phenelzine acetylation in rodent and human liver was corroborated by the ...
W J, Tilstone, P, Margot, E C, Johnstone
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Microsome-free preparations of rodent and human liver were shown to contain N-acetyl transferase from experiments using procainamide as substrate. These preparations then acetylated phenelzine from the quantitative transfer of radiolabeled acetate. This in vitro demonstration of phenelzine acetylation in rodent and human liver was corroborated by the ...
W J, Tilstone, P, Margot, E C, Johnstone
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Acta Crystallographica Section C Crystal Structure Communications, 1988
S-Benzylthio thioacetate, C9H10OS2, Mr = 198.31, monoclinic, P2(1), a = 5.7112(5), b = 8.1912(5), c = 10.6486(8) A, beta = 92.230(8) degrees, V = 497.8(1) A3, Z = 2, Dm = 1.32(1), Dx = 1.323 Mg m-3, lambda(Mo K alpha) = 0.71073 A, mu = 0.47 mm-1, F(000) = 208, T = 299(1) K, RF = 0.024 for 812 reflections. In this molecule, the S-S [2.024(1) A] and S-C [
E, John, J A, Potenza, H J, Schugar
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S-Benzylthio thioacetate, C9H10OS2, Mr = 198.31, monoclinic, P2(1), a = 5.7112(5), b = 8.1912(5), c = 10.6486(8) A, beta = 92.230(8) degrees, V = 497.8(1) A3, Z = 2, Dm = 1.32(1), Dx = 1.323 Mg m-3, lambda(Mo K alpha) = 0.71073 A, mu = 0.47 mm-1, F(000) = 208, T = 299(1) K, RF = 0.024 for 812 reflections. In this molecule, the S-S [2.024(1) A] and S-C [
E, John, J A, Potenza, H J, Schugar
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