Results 251 to 260 of about 230,380 (304)

THE ACETYLATION OF PROTHROMBIN

Canadian Journal of Biochemistry and Physiology, 1960
Purified bovine prothrombin was acetylated to a range of 27 to 30% of its amino groups. Except for just significant amounts it lost its power to generate thrombin-C. Upon activation the yield of thrombin-E was 100% on the basis of the thrombin-C yield that was obtained on an aliquot sample of the prothrombin before acetylation.
R H, LANDABURU, W H, SEEGERS
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Nonenzymic acetylation of histones with acetyl phosphate and acetyl adenylate

Biochemistry, 1975
Nonenzymatic acetylation of calf-thymus lysine- and arginine-rich histones was demonstrated to occur when these proteins were incubated with [14C]acetyl phosphate and [14C]acetyl adenylate. The levels of acetylation depend on both pH and on reagent concentration.
RAMPONI, GIAMPIETRO, MANAO, GIAMPAOLO, CAMICI, GUIDO   +2 more
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Acetyl-CoA, protein acetylation, and liver cancer

Molecular Cell, 2022
Using multi-omics approaches, Park et al. show that reduced cellular acetyl-CoA and protein hypoacetylation promote liver cancer growth and dedifferentiation.
Zhengming, Wu, Kun-Liang, Guan
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Clonazepam acetylation in fast and slow acetylators

Clinical Pharmacology and Therapeutics, 1981
Six slow acetylators (SAs) and six rapid acetylators (RAs), as determined by sulfamethazine (SMZ) phenotyping, were each given a 2-mg oral dose of clonazepam. Ninety-six-hour urine collections from these subjects were analyzed for clonazepam, 7-amino clonazepam (7-AM, clonazepam nitroreduced metabolite), and 7-acetamido clonazepam (7-ACT, N-acetylated ...
Miller, Marvin E., Garland, W. A., Min, B. H., Ludwick, B. T., Ballard, R. H., Levy, R. H.   +5 more
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Nonenzymatic acetylation of histones with acetyl-CoA

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1970
Abstract 1. When purified calf thymus histones were incubated with [1-14C]acetyl-CoA and treated to remove the acid-soluble fraction with trichloroacetic acid, a large amount of radioactivity still remained in the 15 % trichloroacetic acid-insoluble precipitate. 2.
W K, Paik, D, Pearson, H W, Lee, S, Kim
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Acetylation of phenelzine

Psychopharmacology, 1979
Microsome-free preparations of rodent and human liver were shown to contain N-acetyl transferase from experiments using procainamide as substrate. These preparations then acetylated phenelzine from the quantitative transfer of radiolabeled acetate. This in vitro demonstration of phenelzine acetylation in rodent and human liver was corroborated by the ...
W J, Tilstone, P, Margot, E C, Johnstone
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Acetylation of nucleosides and acetyl migration

Tetrahedron, 1968
Abstract Acetylation of the 2′-OH group predominances over acetylation of the 3′-OH group in derivatives of adenosine, uridine, 3β- d -xylosyluracil and 3β- d -lyxosyluracil. In each case subsequent equilibrium of the products of acetylation results in a net acetyl migration away from the glycosidic link.
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A micromethod for the measurement of acetyl phosphate and acetyl coenzyme A

Analytical Biochemistry, 1980
Abstract A method for the determination of acetyl phosphate in cell-free extracts is described. The sensitivity of this method is 20 pmol/ml of extract. An adaptation that permits the measurement of picomole quantities of acetyl CoA is also presented.
A G, Hunt, J, Hong
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