Results 241 to 250 of about 230,380 (304)

Design of Fuel‐Dependent, Complex‐Coacervate‐Based Synthetic Cells

Chemistry – A European Journal, EarlyView.
Fuel‐dependent synthetic cells form and persist only in the presence of chemical fuel, decaying under starvation. We establish design rules for hexapeptide‐based coacervates, showing that tryptophan enhances polyanion binding, extends lifetime, and reduces waste sensitivity.
Anna‐Lena Holtmannspötter, Xiaoyao Chen, Yiyi Fu, Melisa Badem, Phillip S. Weiß, Nicolas Glück, Chase Kanitz, Veronika Rupp, Kaige Wang, Job Boekhoven   +9 more
wiley   +1 more source

Acetylation-triggered degradation of MSX1 impairs palatal development. [PDF]

Cell Death Discov
Meng L, You J, Zhang Z, Jiang Y, Liu Y, Zhou M, Ma J, Jiang X.   +7 more
europepmc   +1 more source

Synthesis and Biological Evaluation of Well‐Defined M6P(n)‐Modified Glycopeptides for Targeted Protein Degradation

Chemistry – A European Journal, EarlyView.
A synthetic methodology has been developed to prepare multifunctional M6P and M6Pn ligands of different valency. The glycopeptides were conjugated to cetuximab and then examined to mediate cellular uptake of fluorescently labeled EGFRvIII. Only cetuximab modified by glycopeptides having 3 or 6 M6P or M6Pn residues demonstrated greater uptake.
Patrycja Lenartowicz, Jan‐Willem H. Langenbach, Nataliia Voloshyna, David Aidukas, Arwin J. Brouwer, John A. W. Kruijtzer, Geert‐Jan Boons   +6 more
wiley   +1 more source

Insulin enables acquisition of the IL7R⁺ memory phenotype in PD1⁺ T cells in RA tissues. [PDF]

Cell Death Dis
Chandrasekaran V, Erlandsson MC, Svensson D, Malmhäll-Bah E, Silfverswärd ST, Pullerits R, Katona G, Bokarewa MI.   +7 more
europepmc   +1 more source

Lactylation at lysine 145 fosters KAT8-TIP60 complex formation to promote p53 acetylation at lysine 120 and its pro-apoptotic function. [PDF]

Nat Commun
Liu H, Li Z, Lei D, Xie H, Yang X, Zhou C, Li S, Li W, Zeng Z, Kang L.   +9 more
europepmc   +1 more source

Inflammation Drives Phosphorylation and Acetylation of MutS Homolog 3 and Interaction with Cytosolic HDAC6. [PDF]

J Cancer
Tseng-Rogenski SS, Koi M, Carethers JM.
europepmc   +1 more source

mTOR-NAA10-C7orf50 axis senses nutritional status to coordinate ribosome biogenesis and autophagy. [PDF]

Sci Adv
Sun J, Yang M, Li Q, Liang J, Feng H, Gao L, Wang Y, Liu H, Guo C, Tang TS.   +9 more
europepmc   +1 more source

CDK1 Phosphorylates KAT8 at Ser348 to Stabilize the MSL Complex and Promote H4K16 Acetylation in Non-Small Cell Lung Cancer. [PDF]

Cells
Chu J, Zhao Q, Ye H, Li M, Wang Y, Xu T, Cai Y, Jin J.   +7 more
europepmc   +1 more source

PTM encoding: decoding the mechanisms of exercise-induced metabolic memory through spatiotemporal modification networks. [PDF]

Front Sports Act Living
Shen Y, Mao Z, Zhang X, Yang Y, Shen Z, He H, Chen C, Liu J.   +7 more
europepmc   +1 more source