Results 261 to 270 of about 328,755 (334)

Digital design and optimization of the integrated synthesis and crystallization process using data‐driven approaches

AIChE Journal, EarlyView.
Abstract This study presents a data‐driven modeling and multi‐objective optimization framework for an integrated section of continuous pharmaceutical manufacturing, focusing on flow synthesis and continuous crystallization. To address data scarcity and trade‐offs among product quality, efficiency, and environmental impact, the framework combines ...
Yiming Ma, Wei Li, Jiaxu Liu, Gao Shang, Huaiyu Yang, Junbo Gong, Zoltan K. Nagy, Brahim Benyahia   +7 more
wiley   +1 more source

The advances in acetylation modification in senescence and aging-related diseases. [PDF]

Front Physiol
Xu M, Wang W, Lu S, Xiong M, Zhao T, Yu Y, Song C, Yang J, Zhang N, Cao L, Sun G, Chen S, Wang P.   +12 more
europepmc   +1 more source

Mycosis Fungoides, Sézary Syndrome, and Cutaneous B‐Cell Lymphomas: 2025 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, EarlyView.
ABSTRACT Disease Overview Primary cutaneous lymphomas are a rare and heterogeneous group of extranodal lymphomas that require the integration of clinical and histopathologic data for classification and treatment. Diagnosis Diagnosis and disease classification is based on histopathologic review and immunohistochemical staining of an appropriate skin ...
Alexandra C. Hristov, Trilokraj Tejasvi, Ryan A. Wilcox   +2 more
wiley   +1 more source

A-485 alleviates postmenopausal osteoporosis by activating GLUD1 deacetylation through the SENP1-Sirt3 signal pathway. [PDF]

J Orthop Surg Res
Ma Y, Zou X, Jian Q, Dong J, Huang X, Zhai Y, Qian L.   +6 more
europepmc   +1 more source

Compound Heterozygous Variants in ZSWIM7 Gene Linked to Infertility and Its Role in Gonadal Development

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT This study aims to elucidate the role of the ZSWIM7 gene in the etiology of infertility, focusing on its potential association with premature ovarian insufficiency and azoospermia. We investigated an 18‐year‐old female patient who presented with primary amenorrhea, hypoplasia of the uterus and ovaries, Tanner stage II breast and pubic hair ...
Denise M. Christofolini, Guilherme Pinn, Thainá Vilella, Maria I. Melaragno, Mariana Moysés‐Oliveira, Luciano Pompei, Rare Genomes Project Consortium, Bianca Bianco, Caio P. Barbosa   +8 more
wiley   +1 more source

Comprehensive multi-omics analysis of histone acetylation modulators identifies ASH1L as a novel aggressive marker for osteosarcoma. [PDF]

Discov Oncol
Ni C, Sun Q, Yin H.
europepmc   +1 more source

Function and regulation of mammalian pyruvate dehydrogenase complex. Acetylation, interlipoyl acetyl transfer, and migration of the pyruvate dehydrogenase component.

, 1979
Richard L. Cate, T.E. Roche
openalex   +1 more source

Phenotypic Characterization of Seven Pediatric Patients Diagnosed With KAT6B‐Related Disorders: Case Series and Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Genitopatellar syndrome (GPS) and Say‐Barber‐Biesecker‐Young‐Simpson Syndrome (SBBYSS) are clinically distinct neurodevelopmental disorders caused by monoallelic pathogenic variants in KAT6B. In some cases, GPS and SBBYSS features can overlap, determining an intermediate phenotype.
Vittorio Maglione, Antonio Pizzuti, Gioia Mastromoro, Eleonora Cresta, Paola Favata, Maria Cristina Digilio, Rossella Capolino, Maria Lisa Dentici, Lorenzo Sinibaldi, Antonio Novelli, Marco Tartaglia, Gianluca Terrin, Viviana Cardilli   +12 more
wiley   +1 more source

Wood modification in Slovenia [PDF]

, 2020
Burnard, Michael David, Kitek Kuzman, Manja, Kutnar, Andreja   +2 more
core   +1 more source

Differential Pasting and Rheological Properties of Diverse Underutilized Starches Modified by Acetic Anhydride and Vinyl Acetate. [PDF]

Foods
Xu S, Gebre BA, Zhang C, Mekonnen SA, Ma M, Zhang H, Sui Z, Corke H.   +7 more
europepmc   +1 more source