Results 1 to 10 of about 452,665 (338)

Effect of the cholinergic system of the lateral periaqueductal gray (lPAG) on blood pressure and heart rate in normal and hydralazine hypotensive rats [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2023
Objective(s): Due to the presence of the cholinergic system in the lateral periaqueductal gray (lPAG) column, the cardiovascular effects of Acetylcholine (ACH) and its receptors in normotensive and hydralazine (HYD) hypotensive rats in this area were ...
Atiyeh Ghorbani   +4 more
doaj   +1 more source

Dopamine and glutamate regulate striatal acetylcholine in decision-making

open access: yesNature, 2023
Experiments in mice provide insight into the dynamic relationship between dopamine and acetylcholine in the ventrolateral striatum and how this signalling circuit affects decision-making and behaviour.
Lynne Chantranupong   +5 more
semanticscholar   +1 more source

FAST (Flexible Acetylcholine Sensing Thread): Real-Time Detection of Acetylcholine with a Flexible Solid-Contact Potentiometric Sensor

open access: yesBioengineering, 2023
Acetylcholine (ACh) is involved in memory and learning and has implications in neurodegenerative diseases; it is therefore important to study the dynamics of ACh in the brain.
Farbod Amirghasemi   +5 more
doaj   +1 more source

An optimized acetylcholine sensor for monitoring in vivo cholinergic activity

open access: yesNature Methods, 2020
The ability to directly measure acetylcholine (ACh) release is an essential step toward understanding its physiological function. Here we optimized the GRABACh (GPCR-activation-based ACh) sensor to achieve substantially improved sensitivity in ACh ...
Miao Jing   +23 more
semanticscholar   +1 more source

Transient receptor potential canonical type 3 channels control the vascular contractility of mouse mesenteric arteries [PDF]

open access: yes, 2014
Transient receptor potential canonical type 3 (TRPC3) channels are non-selective cation channels and regulate intracellular Ca2+ concentration. We examined the role of TRPC3 channels in agonist-, membrane depolarization (high K+)-, and mechanical ...
Abramowitz, Joel   +6 more
core   +5 more sources

The Neuromodulatory Role of the Noradrenergic and Cholinergic Systems and Their Interplay in Cognitive Functions: A Focused Review

open access: yesBrain Sciences, 2022
The noradrenergic and cholinergic modulation of functionally distinct regions of the brain has become one of the primary organizational principles behind understanding the contribution of each system to the diversity of neural computation in the central ...
Cody Slater   +4 more
doaj   +1 more source

Grape Seed Oil as a Natural Therapy in Male Rats with Alzheimer’s Diseases [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2020
Purpose: Alzheimer’s disease (AD) is a chronic neurodegenerative disorder, with an increasing prevalence rate, mostly related to cholinergic system.
Farnoosh Berahmand   +3 more
doaj   +1 more source

Chemical Weapons in the Iran-Iraq War (1980–1988). 6. Accumulated Experience in the Treatment of Lesions with Poisonous Nerve Agents

open access: yesВестник войск РХБ защиты, 2023
The Iran-Iraq war (1980–1988) was the first modern war in which chemical weapons were used. The purpose of this work is to summarize the experience of treating victims, affected by nerve agents. The publications of Iranian authors in different scientific
M. V. Supotnitskiy
doaj   +1 more source

Acetylcholine From Tuft Cells: The Updated Insights Beyond Its Immune and Chemosensory Functions

open access: yesFrontiers in Cell and Developmental Biology, 2020
Tuft cells, rare solitary chemosensory cells, are distributed in mucosal epithelium throughout mammalian organs. Their nomenclatures are various in different organs and may be confused with other similar cells.
Jun Pan   +10 more
doaj   +1 more source

Revisiting the Endocytosis of the M2 Muscarinic Acetylcholine Receptor

open access: yesMembranes, 2015
The agonist-induced endocytosis of the muscarinic acetylcholine receptor M2 is different from that of the other members of the muscarinic receptor family.
Wymke Ockenga, Ritva Tikkanen
doaj   +1 more source

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