Results 1 to 10 of about 288,337 (198)
A study of the ‘desensitization’ produced by acetylcholine at the motor end‐plate
Journal of Physiology, 1957 B. Katz, S. Thesleff
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Dopamine and glutamate regulate striatal acetylcholine in decision-making
Nature, 2023 Experiments in mice provide insight into the dynamic relationship between dopamine and acetylcholine in the ventrolateral striatum and how this signalling circuit affects decision-making and behaviour.
Lynne Chantranupong +5 more
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Frontiers in Neural Circuits, 2022 Acetylcholine (ACh) can act on pre- and post-synaptic muscarinic receptors (mAChR) in the cortex to influence a myriad of cognitive processes. Two functionally-distinct regions of the prefrontal cortex—the lateral prefrontal cortex (LPFC) and the ...
Alexandra Tsolias +2 more
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Chinese Journal of Physiology, 2020 The purpose of this study was to quantitatively assess the difference in sudomotor function between healthy males and females in their early twenties by measuring skin surface area and activated sweat gland density (ASGD). The quantitative sudomotor axon
Tae-Hwan Park +3 more
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An optimized acetylcholine sensor for monitoring in vivo cholinergic activity
Nature Methods, 2020 The ability to directly measure acetylcholine (ACh) release is an essential step toward understanding its physiological function. Here we optimized the GRABACh (GPCR-activation-based ACh) sensor to achieve substantially improved sensitivity in ACh ...
Miao Jing +23 more
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eLife, 2022 The auditory mismatch negativity (MMN) has been proposed as a biomarker of NMDA receptor (NMDAR) dysfunction in schizophrenia. Such dysfunction may be caused by aberrant interactions of different neuromodulators with NMDARs, which could explain clinical ...
Lilian Aline Weber +6 more
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eLife, 2021 The hippocampus plays a central role in long-term memory formation, and different hippocampal network states are thought to have different functions in this process. These network states are controlled by neuromodulatory inputs, including the cholinergic
Przemyslaw Jarzebowski +3 more
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PLoS ONE, 2014 Despite extensive studies on nicotinic acetylcholine receptors (nAChRs) and homologues, details of acetylcholine binding are not completely resolved. Here, we report the crystal structure of acetylcholine bound to the receptor homologue acetylcholine ...
Jeppe A Olsen +4 more
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eLife, 2021 Basal forebrain cholinergic neurons (BFCNs) project throughout the cortex to regulate arousal, stimulus salience, plasticity, and learning. Although often treated as a monolithic structure, the basal forebrain features distinct connectivity along its ...
Blaise Robert +6 more
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