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British Journal of Pharmacology, 2006 This article traces the development of knowledge about the physiology and pharmacology of acetylcholine and its receptors between 1930 and 2005, with emphasis on contributions by members of the British Pharmacological Society, and by other British pharmacologists and physiologists.British Journal of Pharmacology(2006)147, S120–S126.
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Acetylcholine regulation of GnRH neuronal activity: A circuit in the medial septum
Frontiers in Endocrinology, 2023 In vertebrates, gonadotropin-releasing hormone (GnRH)-secreting neurons control fertility by regulating gonadotrophs in the anterior pituitary. While it is known that acetylcholine (ACh) influences GnRH secretion, whether the effect is direct or indirect,
David M. Shostak +3 more
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Cells, 2023 Major features of aging might be progressive decreases in cognitive function and physical activity, in addition to withered appearance. Previously, we reported that the intracerebroventricular injection of human neural stem cells (NSCs named F3) encoded ...
Jangbeen Kyung +7 more
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WormBook, 2007 Acetylcholine is the major excitatory neurotransmitter at nematode neuromuscular junctions, and more than a third of the cells in the C. elegans nervous system release acetylcholine. Through a combination of forward genetics, drug-resistance selections, and genomic analysis, mutants have been identified for all of the steps specifically required for ...
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Lipid Membrane State Change by Catalytic Protonation and the Implications for Synaptic Transmission
Membranes, 2021 In cholinergic synapses, the neurotransmitter acetylcholine (ACh) is rapidly hydrolyzed by esterases to choline and acetic acid (AH). It is believed that this reaction serves the purpose of deactivating ACh once it has exerted its effect on a receptor ...
Christian Fillafer +2 more
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Chemosensors, 2022 A study of the transient potential signals obtained with a cation-selective electrode based on an ion-exchanger was carried out for solutions of the following individual cations at different concentrations: H+, Li+, Na+, K+, Rb+, Mg2+, Ca2+, choline (Ch+)
José Antonio González-Franco +2 more
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Grape Seed Oil as a Natural Therapy in Male Rats with Alzheimer’s Diseases [PDF]
Advanced Pharmaceutical Bulletin, 2020 Purpose: Alzheimer’s disease (AD) is a chronic neurodegenerative disorder, with an increasing prevalence rate, mostly related to cholinergic system.
Farnoosh Berahmand +3 more
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Effects of different sugammadex doses on the train of four ratio recovery progression during rocuronium induced neuromuscular blockade in the rat phrenic nerve hemidiaphragm [PDF]
Korean Journal of Anesthesiology, 2020 Background In this study, we used an ex-vivo model to investigate the recovery pattern of both the train-of-four (TOF) ratio and first twitch tension of TOF (T1), and determined their relationship during recovery from rocuronium-induced neuromuscular ...
Yong Beom Kim +5 more
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Frontiers in Neural Circuits, 2022 Acetylcholine (ACh) can act on pre- and post-synaptic muscarinic receptors (mAChR) in the cortex to influence a myriad of cognitive processes. Two functionally-distinct regions of the prefrontal cortex—the lateral prefrontal cortex (LPFC) and the ...
Alexandra Tsolias +2 more
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Frontiers in Neural Circuits, 2020 The inferior colliculus processes nearly all ascending auditory information. Most collicular cells respond to sound, and for a majority of these cells, the responses can be modulated by acetylcholine (ACh). The cholinergic effects are varied and, for the
William A. Noftz +5 more
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