Results 111 to 120 of about 185,010 (296)

Effects of geranylgeranylacetone on diastolic and microvascular function in patients with heart failure with a preserved ejection fraction: A phase 2, randomized, placebo‐controlled, crossover trial

European Journal of Heart Failure, EarlyView.
Abstract Aims Heart failure with preserved ejection fraction (HFpEF) is a major healthcare burden with limited treatment options. Geranylgeranylacetone (GGA) has been shown to improve myocardial compliance and endothelial function in preclinical models.
Soufiane Nassiri, Geert H.D. Voordes, Loek van Heerebeek, Daniël H. van Raalte, Marianne C. Verhaar, Daan J. Touw, Merle M. Krebber, Dirk J. Duncker, Etto C. Eringa, M. Louis Handoko, Adriaan A. Voors, on behalf of the RECONNEXT Consortium   +11 more
wiley   +1 more source

The distribution of acetylcholine in the peripheral and the central nervous system

, 1941
F. C. MacIntosh
openalex   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Studies on the coronary flow and the oxygen consumption of the isolated dog heart in ventricular fibrillation and the effects of epinephrine, levarterenol, isoproterenol, acetylcholine, 5-hydroxytryptamine, ATP, theophyllin-ethylendiamine, nitroglycerin and papaverine on it.

, 1957
Koroku Hashimoto
openalex   +2 more sources

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Acetylcholin [PDF]

, 2020
Helga Peter, Thomas Penzel
openaire   +1 more source

The influence of temperature on the acetylcholine output from a sympathetic ganglion [PDF]

, 1956
Krista Kostial, Vale Vouk
openalex   +1 more source

Cytotoxicity of 19 Pesticides in Rainbow Trout Gill, Liver, and Intestinal Cell Lines

Environmental Toxicology and Chemistry, EarlyView.
Abstract The rainbow trout gill cell line (RTgill‐W1), via test guideline 249 of the Organisation for Economic Co‐operation and Development, has been established as a promising New Approach Methodology, although to advance confidence in the method more case studies are needed that: 1) expand our understanding of applicability domains (chemicals with ...
Sophie Emberley‐Korkmaz, Krittika Mittal, Na'im Temlock, Jessica Head, Niladri Basu   +4 more
wiley   +1 more source

Medicine‐Food Plant Polysaccharides Modulate Diabetes and Diabetic Complications Through Maintaining Gut Function: A Review

Food Frontiers, EarlyView.
Polysaccharides derived from medicine‐food plants restore intestinal barrier integrity and microbiota balance while modulating short‐chain fatty acid levels. These modifications significantly alleviate diabetes and its complications, including nephropathy, retinopathy, cardiovascular disease, and neuropathy.
Yi Long, Wanglong Yu, Pingping Yang, Minxuan Xu, Jitao Ling, Yuting Wu, Xiao Liu, Liu Ouyang, Yan Xiong, Jianping Liu, Yiming Gan, Jing Zhang, Peng Yu, Deju Zhang   +13 more
wiley   +1 more source

PRESENCE OF ACETYLCHOLINE IN THE MALAYAN JACK‐FRUIT, ARTOCARPUS INTEGRA [PDF]

, 1955
Robert C. Lin
openalex   +1 more source