Results 121 to 130 of about 185,010 (296)

The mechanisms in glucose metabolism of aging hippocampus

open access: yesIbrain, EarlyView.
Cognitive decline in elders stems from the irreversible loss and functional decline of neurons, with the hippocampus being particularly susceptible to age‐related neuronal deterioration. Glucose acts as the primary fuel for the brain, and a constant provision of glucose to the hippocampus is essential for memory and cognitive functions.
Rui He   +6 more
wiley   +1 more source

Perinatal Exposure to the Neonicotinoid Thiacloprid Impacts Transcription of Neuroplasticity and Neuroendocrine Markers in Mice but Not in the Zebrafish Model

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Neonicotinoids are widely used insecticides in agriculture, aquaculture, pet care, and urban pest control. Initially developed to selectively target the insect cholinergic system, their extensive use has raised concerns about adverse effects on nontarget vertebrates.
Kirthana Kunikullaya U   +6 more
wiley   +1 more source

Pyridostigmine as treatment for chronic gastrointestinal dysmotility in a child with Mowat‐Wilson syndrome: A case report and literature review

open access: yesJPGN Reports, EarlyView.
Abstract Gastrointestinal dysmotility is commonly reported among patients with Mowat‐Wilson syndrome (MWS) and poses a significant symptomatic burden. Unfortunately, there remains a knowledge gap regarding effective treatment strategies. A 2‐year‐old male with MWS presented with chronic paradoxical abdominal pain, constipation, and progressively ...
Grace J. Lin   +5 more
wiley   +1 more source

Pediatric intestinal pseudo‐obstruction found in 3‐year‐old male with Rett‐related mutation of methyl‐CpG binding protein 2

open access: yesJPGN Reports, EarlyView.
Abstract A 3‐year‐old male with chronic abdominal distention, constipation, and severe malnutrition is diagnosed with pediatric intestinal pseudo‐obstruction (PIPO) after extensive evaluation that excluded mechanical, malabsorptive, metabolic, inflammatory, and infectious causes. Aside from speech delay, he has a normal neurologic exam.
Angela Tran, Namrata Patel‐Sanchez
wiley   +1 more source

Acute Effects of the 5‐Hydroxytryptamine Type 4 Receptor Agonist Mosapride on Pharyngeal Swallowing Physiology in Adults

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The 5‐hydroxytryptamine type 4 receptor agonist mosapride is known to modulate esophageal peristalsis and enhance lower esophageal sphincter compliance. However, its impact on oropharyngeal swallowing physiology remains insufficiently characterized.
Shu‐Wei Liang   +7 more
wiley   +1 more source

Novel Biomolecule‐Infused Gelatin Injectable for Treatment of Recurrent Laryngeal Nerve Injury

open access: yesThe Laryngoscope, EarlyView.
Biomolecule‐infused gelatin shows promising nerve regeneration, attenuation of muscle atrophy, and functional electromyography outcomes after recurrent laryngeal nerve injury. This biomolecule cocktail may serve as a possible long‐term treatment for vocal fold paralysis and warrants further research in additional animal models.
Ananya Tadikonda   +9 more
wiley   +1 more source

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