Results 111 to 120 of about 227,192 (263)

Multifunctional hyaluronic acid hydrogel integrating exosome‐encapsulating gelatin microspheres accelerates skeletal muscle regeneration via TGF‐β1 activation and enhanced myogenic cell viability

open access: yesBMEMat, EarlyView.
Schematic illustration of preparation of injectable H/G@Co@miR‐206 hydrogel for efficient skeletal muscle regeneration in cardiotoxin‐induced skeletal muscle injury SD rat model. Abstract The effective treatment of acute skeletal muscle injuries remains challenging, necessitating therapeutic strategies that concurrently reestablish vascular perfusion ...
Zhengzhe Han   +9 more
wiley   +1 more source

Nachr subtypes present in the rodent habenulo-interpeduncular pathway and their involvement in 3h-acetylcholine release

open access: yes, 2008
The habenula (Hb) is a diencephalic structure that receives substantial input from multiple parts of the limbic system, and communicates with the nucleus interpeduncularis (IPN) by means of the fasciculus retroflexus.
A. Zanardi   +8 more
core   +1 more source

Septic encephalopathy: does inflammation drive the brain crazy?

open access: yesBrazilian Journal of Psychiatry, 2014
Sepsis and the multiorgan dysfunction syndrome are among the most common reasons for admission to an intensive care unit, and are a leading cause of death.
Felipe Dal-Pizzol   +2 more
doaj   +1 more source

Acetylcholine in extracts and perfusates of urinary bladder

open access: yes, 1967
Tissue extracts of the urinary bladder of the rat, cat and guinea-pig contain an acetylcholine-like substance which is considered to be stored predominantly in post-ganglionic nerve fibres.
G B CHESHER
core   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

open access: yesBMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma   +8 more
wiley   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

open access: yesBMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng   +4 more
wiley   +1 more source

Clinical and neurophysiological characteristics of heterozygous NPC1 carriers

open access: yesJIMD Reports, 2019
Niemann‐Pick disease type C (NPC) is an uncommon lysosomal storage disorder, which is characterized neuropathologically by cholinergic dysfunction and presents clinically with a broad series of neurological signs and symptoms.
Alberto Benussi   +10 more
doaj   +1 more source

Critical Period Regulation by Thyroid Hormones: Potential Mechanisms and Sex-Specific Aspects

open access: yesFrontiers in Molecular Neuroscience, 2019
Adequate perinatal levels of thyroid hormones (THs) are required for normal brain function and development. Studies in non-mammalian species suggest that TH might be involved in the regulation of critical periods (CPs) of heightened plasticity.
Gervasio Batista   +3 more
doaj   +1 more source

Inclusion Complexations of Levamisole and Cocaine With Molecular Baskets. Fluorescence Displacement Assay for Detection of Cocaine and Its Adulterant Levamisole in Aqueous Media

open access: yesChemistry – A European Journal, EarlyView.
Levamisole is a common adulterant found in street‐distributed cocaine. Molecular baskets have been shown to form stable inclusion complexes with both substances. While levamisole inserts its benzene into the basket's cavity, cocaine utilizes its bicyclic ring for encapsulation.
Christopher T. Mortensen   +7 more
wiley   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples   +10 more
wiley   +1 more source

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