Results 21 to 30 of about 432,537 (413)
New reliable and robust potentiometric ion-selective electrodes were fabricated using poly(3,4-ethylenedioxythiophene)/poly(styrenesulfonate) (PEDOT/PSS) as the solid contact between the sensing membrane and electrical substrate for an acetylcholine (ACh)
Nashwa H. Ashmawy+5 more
doaj +1 more source
Acetylcholine (ACh) is believed to act as a neuromodulator in cortical circuits that support cognition, specifically in processes including learning, memory consolidation, vigilance, arousal and attention. The cholinergic modulation of cortical processes
Jennifer J. Coppola, Anita A. Disney
doaj +1 more source
T-cell derived acetylcholine aids host defenses during enteric bacterial infection with Citrobacter rodentium. [PDF]
The regulation of mucosal immune function is critical to host protection from enteric pathogens but is incompletely understood. The nervous system and the neurotransmitter acetylcholine play an integral part in host defense against enteric bacterial ...
Bevins, Charles L+12 more
core +2 more sources
Phospholipases A2 represent the most abundant family of snake venom proteins. They manifest an array of biological activities, which is constantly expanding. We have recently shown that a protein bitanarin, isolated from the venom of the puff adder Bitis
Catherine A Vulfius+9 more
doaj +1 more source
Sex‐Specific Genetic Variants are Associated With Coronary Endothelial Dysfunction
BackgroundEndothelial dysfunction is an early stage of atherosclerosis. Single‐nucleotide polymorphisms (SNPs) have been associated with vascular dysfunction, cardiac events, and coronary artery remodeling.
Satoshi Yoshino+9 more
doaj +1 more source
The inferior colliculus (IC), the midbrain hub of the central auditory system, receives extensive cholinergic input from the pontomesencephalic tegmentum.
Luis M. Rivera-Perez+2 more
doaj +1 more source
Mammalian nicotinic acetylcholine receptors: from structure to function.
The classical studies of nicotine by Langley at the turn of the 20th century introduced the concept of a "receptive substance," from which the idea of a "receptor" came to light.
E. Albuquerque+3 more
semanticscholar +1 more source
Resolution of complex fluorescence spectra of lipids and nicotinic acetylcholine receptor by multivariate analysis reveals protein-mediated effects on the receptor's immediate lipid microenvironment [PDF]
Analysis of fluorescent spectra from complex biological systems containing various fluorescent probes with overlapping emission bands is a challenging task. Valuable information can be extracted from the full spectra, however, by using multivariate analysis (MA) of measurements at different wavelengths.
arxiv +1 more source
Transient receptor potential canonical type 3 channels control the vascular contractility of mouse mesenteric arteries [PDF]
Transient receptor potential canonical type 3 (TRPC3) channels are non-selective cation channels and regulate intracellular Ca2+ concentration. We examined the role of TRPC3 channels in agonist-, membrane depolarization (high K+)-, and mechanical ...
Abramowitz, Joel+6 more
core +2 more sources
Spontaneous Lipid Binding to the Nicotinic Acetylcholine Receptor in a Native Membrane [PDF]
The nicotinic acetylcholine receptor (nAChR) and other pentameric ligand-gated ion channels (pLGICs) are native to neuronal membranes with an unusual lipid composition. While it is well-established that these receptors can be significantly modulated by lipids, the underlying mechanisms have been primarily studied in model membranes with only a few ...
arxiv +1 more source