Results 31 to 40 of about 343,067 (338)
Frontiers in Cellular Neuroscience, 2023 Cholinergic modulation of the brain cortex is critical for cognitive processes, and altered cholinergic modulation of the prefrontal cortex is emerging as an important mechanism of neuropathic pain.
Taylor Jefferson +2 more
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Frontiers in Behavioral Neuroscience, 2022 Introduction: Altered signaling or function of acetylcholine (ACh) has been reported in various neurological diseases, including Alzheimer’s disease, Tourette syndrome, epilepsy among others.
R. Oliver Goral +11 more
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Cholinergic cells in the nucleus basalis of mice express the N-methyl-D-aspartate-receptor subunit NR2C and its replacement by the NR2B subunit enhances frontal and amygdaloid acetylcholine levels [PDF]
, 2006 It is known that glutamatergic and cholinergic systems interact functionally at the level of the cholinergic basal forebrain. The N-methyl-D-aspartate receptor (NMDA-R) is a multiprotein complex composed of NR1, NR2 and/or NR3 subunits.
Broide R.S. +11 more
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Alpha9 nicotinic acetylcholine receptors and the treatment of pain [PDF]
, 2009 Chronic pain is a vexing worldwide problem that causes substantial disability and consumes significant medical resources. Although there are numerous analgesic medications, these work through a small set of molecular mechanisms.
Absalom, Nathan +4 more
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Muscarinic receptors mediate motivation via preparatory neural activity in humans
eLifeMotivation depends on dopamine, but might be modulated by acetylcholine which influences dopamine release in the striatum, and amplifies motivation in animal studies.
John P Grogan +5 more
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A photoisomerizable muscarinic antagonist. Studies of binding and of conductance relaxations in frog heart [PDF]
, 1982 These experiments employ the photoisomerizable compound, 3,3'-bis- [alpha-(trimethylammonium)methyl]azobenzene (Bis-Q), to study the response to muscarinic agents in frog myocardium. In homogenates from the heart, trans-Bis-Q blocks the binding of [3H]-N-
Birdsall, Nigel J. M. +5 more
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Frontiers in Molecular NeuroscienceIntroductionThe pedunculopontine nucleus (PPN) plays a role in coordinating complex behaviors and adapting to changing environmental conditions. The specific role of cholinergic neurons in PPN function is not well understood, but their ascending ...
Yuwoong Kim +3 more
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The Regulatory Effects of Acetyl-CoA Distribution in the Healthy and Diseased Brain
Frontiers in Cellular Neuroscience, 2018 Brain neurons, to support their neurotransmitter functions, require a several times higher supply of glucose than non-excitable cells. Pyruvate, the end product of glycolysis, through pyruvate dehydrogenase complex reaction, is a principal source of ...
Anna Ronowska +7 more
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Effect of lithium on acetylcholine esterase activity, and isozyme pattern in developing chick brain [PDF]
, 2004 Acetylcholine Esterase is an enzyme, which hydrolyses acetylcholine and is used as a marker for cholinergic neural function. It is known to be involved in synaptogenesis.
Gouri, Ms Anahita +3 more
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Acetylcholine and Acetylcholine Receptors in Taste Receptor Cells [PDF]
Chemical Senses, 2005 Neuroactive substances play important roles as transmitters and neuromodulators. Although many of these substances and/or their receptors are known to be present in taste receptor cells and nerve fibers innervating taste buds, physiological functions of these substances are not well understood (Nagai et al., 1996).
Tatsuya, Ogura, Weihong, Lin
openaire +2 more sources