Results 151 to 160 of about 124,177 (265)

The Second Hit Hypothesis in Animal and Human Dystonia: The Role of Peripheral Nerve Trauma and Spinal Cord Injury

Movement Disorders, EarlyView.
The “second‐hit” hypothesis proposes that both a genetic predisposition and an environmental insult—such as peripheral nerve trauma or spinal cord injury—are required for dystonia development. This review explores how neuroinflammation and maladaptive plasticity, triggered by nerve and spinal cord injury, contribute to dystonia pathogenesis.
Lisa Harder‐Rauschenberger, Chi Wang Ip   +1 more
wiley   +1 more source

Structural insights into the progressive recovery of α7 nicotinic acetylcholine receptor from nicotine-induced desensitization. [PDF]

Sci Adv
Liu S, Chen H, Zhu X, Ye F, Zhao Y, Qin J, Zheng Y, Wang X, Zhang L, Chen H, Li X, Mu W, Fu Y, Luo C, Hou H, Bai C, Liu L, Tian C.   +17 more
europepmc   +1 more source

The Sleep–Wake Cycle in the Nicotinic Alpha-9 Acetylcholine Receptor Subunit Knock-Out Mice [PDF]

, 2017
Natalia Madrid-López, Jorge L. Estrada, Javier Díaz, Alejandro Bassi, Paul H. Délano, Adrián Ocampo-Garcés   +5 more
openalex   +1 more source

Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors

Medicinal Research Reviews, EarlyView.
ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara, Gómez‐Santacana Xavier, Llebaria Amadeu, Rovira Xavier   +3 more
wiley   +1 more source

Serum Levels of Alpha7 Nicotinic Acetylcholine Receptor and Their Association With Cardiovascular Autonomic Function Tests in Healthy Young Adults. [PDF]

Cureus
Karthik S, Elakiya M, Balamurugesan K.
europepmc   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Antifibrotic Effects of an α7 Nicotinic Acetylcholine Receptor Agonist in Keloid Fibroblasts and a Rat Scar Model. [PDF]

Int J Mol Sci
Roh H, Kim YH, Heo KJ, Hong JW, Lee WJ.
europepmc   +1 more source

Post Hoc, Sex‐Specific Subgroup Analysis of Efgartigimod in Patients With Generalized Myasthenia Gravis From the ADAPT Trial: A Sex and Gender Equity in Research (SAGER) Guidelines Approach

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Sex‐specific differences in myasthenia gravis (MG) are widely acknowledged, yet data on sex‐based outcomes of MG treatment are scarce. In accordance with Sex and Gender Equity in Research guidelines, this post hoc analysis assessed potential sex‐specific differences in treatment outcomes in acetylcholine receptor antibody ...
Sarah Hoffmann, Sihui Zhao, Filip Callewaert, Silke Schoppe, Csilla Rózsa, Jennifer Spillane   +5 more
wiley   +1 more source

Nicotine in e-cigarette aerosol reduces GABA neuron migration via the α7 nicotinic acetylcholine receptor. [PDF]

Sci Rep
Parnell AA, McCarthy DM, Trupiano MX, Schatschneider C, Bhide PG.   +4 more
europepmc   +1 more source

Fluorescent staining of acetylcholine receptors in vertebrate skeletal muscle

, 1974
Mitchell J. Anderson, M.W. Cohen
openalex   +2 more sources