Results 21 to 30 of about 116,282 (198)
Expression and function of nicotinic acetylcholine receptors in stem cells
AIMS Bioengineering, 2016 Nicotinic acetylcholine receptors are prototypical ligand gated ion channels typically found in muscular and neuronal tissues. Functional nicotinic acetylcholine receptors, however, have also recently been identified on other cell types, including stem ...
Herman S. Cheung +2 more
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eLife, 2022 Human adult muscle-type acetylcholine receptors are heteropentameric ion channels formed from two α-subunits, and one each of the β-, δ-, and ε-subunits.
Christian JG Tessier +5 more
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Critical Care, 2018 Acetylcholine receptor antagonists have been shown to improve outcome in patients with severe acute respiratory distress syndrome. However, it is incompletely understood how these agents improve outcome.
Diana Jansen +2 more
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THE NATURE OF ACETYLCHOLINE RECEPTOR [PDF]
Acta Medica Iranica, 1983 The present work with consideratlon to the autoradiographic pictures, suggests that cholinergic receptors are located at the gate of a channel originating from synaptic cleft coming to lie within the muscle fibre. AChE molecules stand at the gate of this
M.E. TASHAYOD
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Anti-inflammation of spirocyclopiperazinium salt compound LXM-10 targeting α7 nAChR and M4 mAChR and inhibiting JAK2/STAT3 pathway in rats. [PDF]
PLoS ONE, 2013 The present study aims to investigate the therapeutic effects of LXM-10 by intragastric administration in both acute and chronic inflammatory models, and to explore the underlying molecular mechanisms.
Weiwei Zhang +5 more
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BMC Neurology, 2019 Background Myasthenia gravis is the most common disease affecting the neuromuscular junction. The most common etiology among patients with juvenile myasthenia gravis is the production of antibodies against the acetylcholine receptor.
Cheng-Che Chou +13 more
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Recent Duplication and Functional Divergence in Parasitic Nematode Levamisole-Sensitive Acetylcholine Receptors. [PDF]
PLoS Neglected Tropical Diseases, 2016 Helminth parasites rely on fast-synaptic transmission in their neuromusculature to experience the outside world and respond to it. Acetylcholine plays a pivotal role in this and its receptors are targeted by a wide variety of both natural and synthetic ...
Thomas B Duguet +6 more
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Critical Care Research and Practice, 2021 After the introduction of suxamethonium in 1953, cases of cardiac arrest during induction of anesthesia were recorded. In the following years, hyperkalemia was identified as the cause, and the connection to acetylcholine receptor modulation as the ...
Henrik Lynge Hovgaard, Peter Juhl-Olsen
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Acetylcholine release and inhibitory interneuron activity in hippocampal CA1
Frontiers in Synaptic Neuroscience, 2014 Acetylcholine release in the central nervous system (CNS) has an important role in attention, recall and memory formation. One region influenced by acetylcholine is the hippocampus, which receives inputs from the medial septum and diagonal band of Broca ...
A. Rory McQuiston
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Anti-Kv1.4 Antibody Without Myasthenia Gravis
JACC: Case Reports, 2023 Anti-Kv1.4 antibody is often detected in thymoma-associated myasthenia gravis patients with anti-acetylcholine receptor antibody. Herein, we describe 2 patients with concurrent myocarditis and myositis.
Naoto Kuyama, MD +12 more
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