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Genetic and pharmacological targeting of nicotinic acetylcholine receptor action blocks tumor progression in mouse models of breast cancer. [PDF]

J Immunol
Heard MA, Qian J, Sayeed S, Mechlowicz S, Zhang Q, Yeluri S, Pool K, Yamane R, Morris GP, Eliceiri BP.   +9 more
europepmc   +1 more source

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Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation

Nature, 2002
Hong Wang, Man Yu, M. Ochani, C. Amella, Mahira Tanović, Seenu M. Susarla, J. Li, Haichao Wang, Huan Yang, Luis Ulloa, Y. Al-Abed, C. Czura, K. Tracey   +12 more
semanticscholar   +3 more sources

Acetylcholine receptor channel imaged in the open state

Nature, 1995
N. Unwin
semanticscholar   +3 more sources

Acetylcholine receptors

Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1975
a-Bungarotoxin is one of a class of proteins, isolated from snake venoms, which antagonize the action of acetylcholine at vertebrate neuromuscular junctions and ‘electroplaques' of electric fish. a-Bungarotoxin blocks acetylcholine action irreversibly and may be labelled with either 125 I or 3
D P, Green, R, Miledi, M, Perez de la Mora, A, Vincent   +3 more
openaire   +2 more sources

Muscarinic Acetylcholine Receptors

Current Pharmaceutical Design, 2006
Muscarinic acetylcholine receptors mediate diverse physiological functions. At present, five receptor subtypes (M(1) - M(5)) have been identified. The odd-numbered receptors (M(1), M(3), and M(5)) are preferentially coupled to G(q/11) and activate phospholipase C, which initiates the phosphatidylinositol trisphosphate cascade leading to intracellular ...
Masaru, Ishii, Yoshihisa, Kurachi
openaire   +2 more sources

α9: An acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells

Cell, 1994
A. Elgoyhen, David S. Johnson, J. Boulter, D. Vetter, S. Heinemann   +4 more
semanticscholar   +3 more sources

Muscarinic acetylcholine receptor

Progress in Neurobiology, 1978
ABSTRACT Muscarinic acetylcholine receptors from rat cerebral cortex and small intestine were studied by the high affinity and high specific activity antagonists 3 H-3-quinuclidinyl benzilate (3-QNB) (29.4 Ci/mmol) and 3 H-N-methyl-4-piperidinyl benzilate (4-NMPB) (55.4 Ci/mmol).
E, Heilbronn, T, Bartfai
openaire   +2 more sources

Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor

Nature, 1986
T. Kubo, K. Fukuda, A. Mikami, A. Maeda, Hideo Takahashi, M. Mishina, T. Haga, K. Haga, A. Ichiyama, K. Kangawa, M. Kojima, H. Matsuo, T. Hirose, S. Numa   +13 more
semanticscholar   +3 more sources

Nicotinic Acetylcholine Receptors

2003
Publisher Summary This chapter deals with nicotinic acetylcholine receptors. Nicotinic acetylcholine receptors (nAChRs) are cholinergic receptors that form ligand-gated ion channels in the plasma membranes of certain neurons and on the postsynaptic side of the neuromuscular junction. As ionotropic receptors, nAChRs are directly linked to ion channels
openaire   +2 more sources

Isolation of Acetylcholine Receptors

Annual Review of Pharmacology, 1972
When ACh acts in an excitatory way, it increases the conductance of a post-synaptic membrane for Na+ and K+, leading to membrane depolariza­ tion. We shall use the term acetylcholine receptor (AChR) for those ma­ cromolecules involved in this transduction that bear the recognition site( s) for ACh and other cholinergic ligands.
R D, O'Brien, M E, Eldefrawi, A T, Eldefrawi   +2 more
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