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Nicotinic acetylcholine receptor at 9 A resolution.
Journal of Molecular Biology, 1993The nicotinic acetylcholine receptor is a cation-selective, ligand-gated ion channel, involved in signal transmission at the chemical synapse. This paper reports the three-dimensional appearance of the channel in the closed conformation, at 9 A ...
N. Unwin
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Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation
Nature, 2002Hong Wang +12 more
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Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
Journal of Molecular Biology, 2005N. Unwin
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Antibodies to the Acetylcholine Receptor
1984The nicotinic acetylcholine receptor (AChR) is one of the key proteins governing the function of the neuromuscular junction. It is the first neurotransmitter receptor to be identified as a molecular entity and to be isolated and purified in an active form.
Miry C. Souroujon +2 more
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Structure and gating mechanism of the acetylcholine receptor pore
Nature, 2003A. Miyazawa, Y. Fujiyoshi, N. Unwin
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2000
Publisher Summary Acetylcholine receptors (AChR) come in two major subtypes, nicotinic and muscarinic, which are named for the agonists that activate them: nicotine and muscarine. Mutations in muscle nAChR subunits produce the congenital fast and slow channel syndromes, while mutations in neuronal nAChRs have been found in nocturnal frontal lobe ...
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Publisher Summary Acetylcholine receptors (AChR) come in two major subtypes, nicotinic and muscarinic, which are named for the agonists that activate them: nicotine and muscarine. Mutations in muscle nAChR subunits produce the congenital fast and slow channel syndromes, while mutations in neuronal nAChRs have been found in nocturnal frontal lobe ...
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Chapter 13: Evolution and acetylcholine receptors
1993Publisher Summary It has emerged in the past few years that the great majority of receptors for neurotransmitters belong to just two structural classes— namely, the ion channel receptor to which the nicotinic receptor belongs and the G-protein coupled receptor to which the muscarinic receptor belongs.
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Acetylcholine receptors in water
Supramolecular Chemistry, 2017This review focuses on the recognition and the detection of the acetylcholine neurotransmitter by artificial receptors, in water and buffered water.
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