Results 261 to 270 of about 125,133 (347)

Hippocampal‐Specific Insulin Resistance Elicits Synaptic Effects on Glutamate Neurotransmission

Journal of Neurochemistry, Volume 169, Issue 6, June 2025.
In animals with hippocampal‐specific insulin resistance, reduced vGluT2 and synaptophysin expression resulted in lowered synaptic glutamate concentrations. These animals also exhibited reduced serine phosphorylation of GluA1 (green postsynaptic receptor) and reduced expression of GluN2B (purple postsynaptic receptor).
Jennifer M. Erichsen, Jennifer L. Woodruff, Claudia A. Grillo, Gerardo G. Piroli, Jim R. Fadel, Lawrence P. Reagan   +5 more
wiley   +1 more source

Neonatal Congenital Myasthenic Syndrome Linked to CHAT Gene Variants: A Case Report and Treatment Insights. [PDF]

Am J Case Rep
Khalil MR, Laulund LW, Aavild Ploug AJ, Elle IC, Fenger-Groen J.   +4 more
europepmc   +1 more source

Quantitative simulation of endplate currents at neuromuscular junctions based on the reaction of acetylcholine with acetylcholine receptor and acetylcholinesterase

, 1979
Terrone L. Rosenberry
openalex   +1 more source

Turnover Time of Acetylcholinesterase

Journal of Biological Chemistry, 1961
openaire   +3 more sources

Altered Vesicular Acetylcholine Transporter Expression Regulates Acetylcholine Abundance in the Brain of Drosophila melanogaster

Journal of Neurochemistry, Volume 169, Issue 6, June 2025.
The vesicular acetylcholine transporter (VAChT) packages and transports the neurotransmitter acetylcholine (ACh) into synaptic vesicles for exocytosis, and its activity is necessary for essential life functions such as locomotion and cognition. Yet, the mechanism through which this important protein mediates ACh release is not fully understood. Here we
Rohina A. Nemat, Timothy Chaya, Angeline‐Claudia Atheby, Hakeem O. Lawal   +3 more
wiley   +1 more source

Loss of Pathogenicity and Evidence of Horizontal Gene Transfer in Colletotrichum gloeosporioides From a Medicinal Plant

Molecular Plant Pathology, Volume 26, Issue 6, June 2025.
A Colletotrichum gloeosporioides strain from Huperzia serrata lacks key pathogenicity genes CgDN3 and cap20 and has fewer pelB, pnl and pg genes. pksIII, for synthesis of huperzine A, was probably acquired by the host plant from the fungus. ABSTRACT Colletotrichum gloeosporioides is a major agricultural pathogen of crops that has also been identified ...
Xizhen Yue, Jia Yang, Jiale Qi, Shanshan Gao, Qingmiao Huo, Xinxin Guo, Hongwei Guo, Jinmei Luo, Yiran Wang, Yirui Zhao, Rongxing Liu, He Wang, Shichen Yi, Yanping Fu, Xu Ji, Yahui Wei, Wei He, Bin Guo   +17 more
wiley   +1 more source

Purification by Affinity Chromatography of the Molecular Forms of Acetylcholinesterase Present in Fresh Electric-Organ Tissue of Electric Eel

, 1972
Yadin Dudai, Israel Silman, Meir Shinitzky, Shmaryahu Blumberg   +3 more
openalex   +1 more source

Elucidating the enzyme network driving Amaryllidaceae alkaloids biosynthesis in Leucojum aestivum

Plant Biotechnology Journal, Volume 23, Issue 6, Page 1988-2005, June 2025.
Schematic representation of Amaryllidaceae alkaloid biosynthesis in Leucojum aestivum. Norbelladine synthase (LaNBS) and noroxomaritidine/norcraugsodine reductase (LaNRII) catalyze the condensation of tyramine and 3,4‐dihydroxybenzaldehyde to form norbelladine, which is subsequently O‐methylated by norbelladine‐4′‐O‐methyltransferase (LaN4′OMT ...
Basanta Lamichhane, Sarah‐Eve Gélinas, Natacha Merindol, Manoj Koirala, Karen Cristine Gonçalves dos Santos, Hugo Germain, Isabel Desgagné‐Penix   +6 more
wiley   +1 more source

Chemoenzymatic Total Synthesis of Lansai B

Chemistry – A European Journal, Volume 31, Issue 26, May 8, 2025.
Lansai B was obtained in a chemoenzymatic approach from the small building block 5‐bromoindole utilizing two enzymes. Applying a tryptophan synthase and a further characterized C3‐methyltransferase the sterically demanding framework is constructed within just six steps. After late‐stage Suzuki‐coupling and n‐methylation the natural product was isolated.
Marcel Schatton, Mona Haase, Julia Tenhaef, Catharina Gronkowsky, Stephan Noack, Jörg Pietruszka   +5 more
wiley   +1 more source

Evaluating the effects of pharmaceutical pollutants on common carp (<i>Cyprinus carpio</i>): histopathological and antioxidant responses. [PDF]

Front Physiol
Shaalan WM, Idriss SKA, Lee JS, Mohamed NH, Sayed AEH.   +4 more
europepmc   +1 more source