Results 261 to 270 of about 176,114 (393)

Spliceosome protein alterations differentiate hubs of the default mode connectome during the progression of Alzheimer's disease

Brain Pathology, Volume 35, Issue 5, September 2025.
Default mode network (DMN) consists, in part, of the frontal (FC), precuneus (PreC), and posterior cingulate cortex (PCC), which plays a critical role in episodic memory and retrieval of autobiographical memories, displays spatiotemporal differences in the onset of amyloid and hypometabolism that reflects tau neurodegeneration and loss of connectivity ...
Sylvia E. Perez, Muhammad Nadeem, Bin He, Jennifer C. Miguel, David G. Moreno, Marta Moreno‐Rodriguez, Michael Malek‐Ahmadi, Chadwick M. Hales, Elliott J. Mufson   +8 more
wiley   +1 more source

Treatment Patterns and Disease Burden of Juvenile Myasthenia Gravis in the United States: A Cohort Study Using Health Care Claims Databases. [PDF]

Neurology
Zhou J, Nilius S, Pilipczuk O, Scowcroft A, Tarancón T, Tennigkeit F, Zaremba P, Chandra N, Kuntz N, Strober J, Brandsema J.   +10 more
europepmc   +1 more source

Morin hydrate reduces survival and fertility, delays development and weakens lipid reserves in Aedes aegypti

Medical and Veterinary Entomology, Volume 39, Issue 3, Page 592-602, September 2025.
Morin hydrate promoted mortality and reduced the rate of pupation and egg laying in Aedes aegypti larvae that survive treatment. Morin hydrate reduces the levels of triacylglycerol, the main lipid reserve in A. aegypti larvae. The expression of proteins involved in lipogenesis and lipolysis was downregulated and upregulated, respectively, in larvae ...
Luan Valim dos Santos, Elaine Rodrigues Miranda Nery da Silva, Matheus Silva Caiado, Renan Albuquerque Camasmie, Herbert Marcusi Souza de Agustini, Raquel do Nascimento de Souza, Bruno Guimarães Marinho, Rosane Nora Castro, Mario Geraldo de Carvalho, Emerson Guedes Pontes   +9 more
wiley   +1 more source

Epidemiology and patient characteristics of the US myasthenia gravis population: real-world evidence from a large insurance claims database. [PDF]

BMJ Neurol Open
Miller-Wilson LA, Arackal J, Edwards Y, Schwinn J, Rockstein KE, Venker B, Nowak RJ.   +6 more
europepmc   +1 more source

Studies on the rare of central catecholaminergic mechanisms in the antidotal effect of the oxime HI 6 in soman poisoned mice [PDF]

, 1988
Arbogast, Helmut, Hallek, M., Reithmann, C., Szinicz, L.   +3 more
core  

The first 25 years of the Northwestern University SuperAging Program

Alzheimer's &Dementia, Volume 21, Issue 8, August 2025.
Abstract During late life, “average” does not mean “intact.” For example, cross‐sectional data from a common word list learning test show that average delayed word recall raw score at age 80 (5/15) is approximately half that at age 56 to 66 (9/15). Cognitive and neurobiological dissolution is therefore implicitly incorporated into concepts of the aging
Sandra Weintraub, Tamar Gefen, Changiz Geula, M‐Marsel Mesulam   +3 more
wiley   +1 more source

Essential Oil of <i>Lippia origanoides</i> Kunth: Nanoformulation, Anticholinesterase Activity, and Molecular Docking. [PDF]

Molecules
Júnior AQDS, Rodrigues GDS, Barroso AS, Figueiredo PLB, Machado FP, Ferreira MA, Fernandes CP, Santos GBD, Mourão RHV.   +8 more
europepmc   +1 more source

Quantitative simulation of endplate currents at neuromuscular junctions based on the reaction of acetylcholine with acetylcholine receptor and acetylcholinesterase

, 1979
Terrone L. Rosenberry
openalex   +1 more source

Astrovascular decoupling in awake 5×FAD mice is associated with reduced astrocytic calcium

Alzheimer's &Dementia, Volume 21, Issue 8, August 2025.
Abstract INTRODUCTION Evidence points to dysregulated Ca2+ in neurons and astrocytes in models of amyloidosis. While most of these data were obtained in vitro or in vivo under anesthesia, less work has investigated these variables in awake ambulating mice.
Ruei‐Lung Lin, Sophiya L. Sims, Nicholas A. Wright, Léopoldine B. Galopin, Blaine E. Weiss, Susan D. Kraner, Jacquelyn E. Rhinehart, Ting‐Hsuan Lu, Pradoldej Sompol, Christopher M. Norris, Olivier Thibault   +10 more
wiley   +1 more source

Utilizing ADMET Analysis and Molecular Docking to Elucidate the Neuroprotective Mechanisms of a Cannabis-Containing Herbal Remedy (Suk-Saiyasna) in Inhibiting Acetylcholinesterase. [PDF]

Int J Mol Sci
Sumontri S, Eiamart W, Tadtong S, Samee W.   +3 more
europepmc   +1 more source