Results 11 to 20 of about 88,160 (292)

Modification of antidote therapy for poisoning due to massive admission of paracetamol

Трансплантология (Москва), 2022
Background. Paracetamol poisoning is common all over the world, including in Russia. In 20–25% of cases, a massive dose of the drug is observed: more than 30–40 g of paracetamol at a time.The aim of the study was to demonstrate the efficacy of using an ...
A. Yu. Simonova, M. M. Potskhveriya, M. V. Belova, K. K. Ilyashenko, N. E. Stolbova, Yu. A. Kurilkin   +5 more
doaj   +1 more source

Dissolution of Biofilm Secreted by Three Different Strains of Pseudomonas aeruginosa with Bromelain, N-Acetylcysteine, and Their Combinations

Applied Sciences, 2021
Bacterial infection of hernia mesh with the formation of biofilms presents a barrier to antibiotic treatment with subsequent surgical intervention and hospitalization.
Carly J. Carter, Krishna Pillai, Samina Badar, Ahmed H. Mekkawy, Javed Akhter, Thomas Jefferies, Sarah J. Valle, David L. Morris   +7 more
doaj   +1 more source

Outcomes after angiography with sodium bicarbonate and acetylcysteine [PDF]

, 2018
Background: Intravenous sodium bicarbonate and oral acetylcysteine are widely used to prevent acute kidney injury and associated adverse outcomes after angiography without definitive evidence of their efficacy.
,, Androsenko, Maria, Bhatt, Deepak L., Brophy, Mary, Cass, Alan, Chertow, Glenn M., Conner, Todd A., Ferguson, Ryan, Gallagher, Martin, Garcia, Santiago, Jneid, Hani, Kaufman, James, McFalls, Edward O., Myles, John, Palevsky, Paul M., Parikh, Chirag R., Shunk, Kendrick, Thwin, Soe-Soe, Weisbord, Steven D., Wu, Hongsheng   +19 more
core   +1 more source

Acute Paracetamol Toxicity: A Study of Severity Assessment and Management at Alexandria Poison Control Center" [PDF]

Asia Pacific Journal of Medical Toxicology
Background: Paracetamol poisoning is a common cause of drug-induced liver injury, especially due to its widespread availability. This study evaluates the frequency, clinical presentation, severity, and treatment outcomes of acute paracetamol toxicity ...
Manal Abdel El-Aziz, Riham Elkassass, Hanaa Elhoshy, Nourhan Saeed   +3 more
doaj   +1 more source

Drug repurposing for reducing the risk of cataract extraction in patients with diabetes mellitus: integration of artificial intelligence-based drug prediction and clinical corroboration

Frontiers in Pharmacology, 2023
Diabetes mellitus (DM) increases the incidence of age-related cataracts. Currently, no medication is approved or known to delay clinical cataract progression.
Zhenxiang Gao, Maria Gorenflo, Maria Gorenflo, David C. Kaelber, Vincent M. Monnier, Rong Xu   +5 more
doaj   +1 more source

Effects of N-acetylcysteine on amphetamine-induced sensitization in mice

Brazilian Journal of Psychiatry, 2017
Objective: N-acetylcysteine (NAC) is beneficial in psychiatric conditions, including schizophrenia. Patients with schizophrenia exhibit mesolimbic dopamine hyperfunction consequent to an endogenous sensitization process. This sensitization can be modeled
Ana P. Herrmann, Roberta Andrejew, Radharani Benvenutti, Clarissa S. Gama, Elaine Elisabetsky   +4 more
doaj   +1 more source

Reduction in Phencyclidine Induced Sensorimotor Gating Deficits in the Rat Following Increased System Xc − Activity in the Medial Prefrontal Cortex [PDF]

, 2013
Rationale: Aspects of schizophrenia, including deficits in sensorimotor gating, have been linked to glutamate dysfunction and/or oxidative stress in the prefrontal cortex. System xc −, a cystine–glutamate antiporter, is a poorly understood mechanism that
A Araque, A Kulak, A Wilmsmeier, B Moghaddam, B Moghaddam, B Oranje, BJ Morris, D Braff, D Lobner, D Matsuzawa, D Piani, DA Baker, DA Baker, David A. Baker, DH Ingvar, DL Braff, DV Pow, FK Graham, G Battaglia, G Franzen, G Paxinos, G Paxinos, G Rajkowska, HH Chen, J Cilia, JA Lieberman, JH Cabungcal, JI Sagara, Jon Resch, JT Coyle, K Japha, K Moussawi, K Moussawi, K Ogita, K Schwabe, K Shimosato, KE Poskanzer, KF Berman, KQ Do, Krista Qualmann, KS Kau, L Deserno, L Pasti, LA Glantz, Linghai Kong, LJ Garey, M Berk, M Berk, M Koch, M Li, M Raffa, MA Geyer, MC Angulo, ME Jackson, MJ Marino, MM Moran, NA Oberheim, NM Veelen van, NR Swerdlow, NR Swerdlow, NR Swerdlow, NR Swerdlow, O Kranich, P Bezzi, P Steullet, R Bridges, R Gysin, R Janaky, S Bannai, S Bannai, S Bannai, SG Potkin, SuJean Choi, T Majic, V Kumari, V Parpura, Victoria Lutgen, VM Goghari, VP Bakshi, WE Bunney, Y Cho, ZC Ye   +81 more
core   +2 more sources

N-Acetylcysteine Compared to Metformin, Improves The Expression Profile of Growth Differentiation Factor-9 and Receptor Tyrosine Kinase c-Kit in The Oocytes of Patients with Polycystic Ovarian Syndrome [PDF]

International Journal of Fertility and Sterility, 2018
Background Paracrine disruption of growth factors in women with polycystic ovarian syndrome (PCOS) results in production of low quality oocyte, especially following ovulation induction.
Ebrahim Cheraghi, Malek Soleimani Mehranjani, Seyed Mohammad Ali Shariatzadeh, Mohammad Hossein Nasr Esfahani, Behrang Alani   +4 more
doaj   +1 more source

Long-Term Treatment of Unresectable Pseudomyxoma Peritonei with Multiple Treatments of Intratumoural Bromelain and Acetylcysteine (BromAc®): A Case Report

Case Reports in Oncology, 2023
Pseudomyxoma peritonei is a rare peritoneal malignancy characterized by the progressive accumulation of mucinous material and tumour within the abdomen and pelvis.
Jessica Yang, Derek Glenn, Suhrid Lodh, Sarah Valle, David Lawson Morris   +4 more
doaj   +1 more source

Contrast-associated acute kidney injury : does it really exist, and if so, what to do about it? [PDF]

, 2019
For decades, when contrast agents are administrated, physicians have been concerned because of the risk of inducing acute kidney injury (AKI). Recent literature questions the existence of AKI induced by contrast, but animal studies clearly showed harmful
Hoste, Eric, Vandenberghe, Wim
core   +2 more sources