Results 61 to 70 of about 83,041 (240)
Nitrates for the Management of Acute Heart Failure Syndromes, A Systematic Review [PDF]
, 2016 © The Author(s) 2016Intravenous nitrates are widely used in the management of acute heart failure syndrome (AHFS) yet with lack of robust evidence to support their use.
Farag, Mohamed +2 more
core +2 more sources
Autism Research, EarlyView.ABSTRACT Recent studies have implicated oxidative stress in the pathophysiology of autism spectrum disorder (ASD). Postmortem brain studies have revealed decreased levels of the reduced form of glutathione (GSH), an important antioxidant, in some brain regions in individuals with ASD; however, in vivo evidence is lacking.
Toshiki Iwabuchi +10 more
wiley +1 more source
Contrast-induced acute kidney injury and renal support for acute kidney injury : a KDIGO summary (part 2) [PDF]
, 2013 Acute kidney injury (AKI) is a common and serious problem affecting millions and causing death and disability for many. In 2012, Kidney Disease: Improving Global Outcomes completed the first ever international multidisciplinary clinical practice ...
Kellum, John A, Lameire, Norbert
core +2 more sources
Oxidative Stress Modulation and Antileishmanial Activity of Salvinia auriculata
Chemistry &Biodiversity, EarlyView.Ethanolic extract of Salvinia auriculata showed significant antioxidant and antileishmanial activities. Salviniside II, the major metabolite, was isolated, structurally characterized, and evaluated, but exhibited weaker antiparasitic effects when compared to the whole extract.
Augusto César Rodrigues +6 more
wiley +1 more source
Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives
ChemPlusChem, EarlyView.Nitroso (hetero)aromatic compounds are bioactive molecules with antiviral, anticancer, neuroprotective, and antimicrobial properties. This review highlights their mechanisms of action—oxidative stress, DNA damage, and enzyme inhibition—alongside synthesis, structure–activity relationships, and toxicity challenges, offering insight into their ...
Silvia Roscales, Aurelio G. Csáky
wiley +1 more source
A look inside the association codeine-paracetamol: clinical pharmacology supports analgesic efficacy [PDF]
, 2015 Acute and chronic pain often requires a multimodal approach. Combination therapy reduces the number of individual daily administrations and improves patient's compliance with the prescribed analgesic treatment. Despite the association codeine/paracetamol
COLUZZI, FLAMINIA, MATTIA, Consalvo
core
Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis. [PDF]
, 2013 Miner1 is a redox-active 2Fe2S cluster protein. Mutations in Miner1 result in Wolfram Syndrome, a metabolic disease associated with diabetes, blindness, deafness, and a shortened lifespan.
Andreyev, Alexander Y +12 more
core +1 more source
Considerations for drug trials in hypertrophic cardiomyopathy
ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant +17 more
wiley +1 more source
16 N-ACETYLCYSTEINE THERAPY OF CHILDHOOD ACETAMINOPHEN OVERDOSE [PDF]
, 1978 Barry H. Rumack +2 more
openalex +1 more source