Results 11 to 20 of about 218,218 (394)
Identification of acetylated diether lipids in halophilic Archaea
MicrobiologyOpen, 2022 As a hallmark of Archaea, their cell membranes are comprised of ether lipids. However, Archaea‐type ether lipids have recently been identified in Bacteria as well, with a somewhat different composition: In Bacillales, sn‐glycerol 1‐phosphate is ...
Cosimo Kropp +6 more
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Optimized bisubstrate inhibitors for the actin N-terminal acetyltransferase NAA80
Frontiers in Chemistry, 2023 Acetylation of protein N-termini is one of the most common protein modifications in the eukaryotic cell and is catalyzed by the N-terminal acetyltransferase family of enzymes.
Line M. Myklebust +8 more
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Acetyltransferases and tumour suppression [PDF]
Breast Cancer Research, 2000 The acetyltransferase p300 was first identified associated with the adenoviral transforming protein E1A, suggesting a potential role for p300 in the regulation of cell proliferation. Direct evidence demonstrating a role for p300 in human tumours was lacking until the recently publication by Gayther et al, which strongly supports a role for p300 as a ...
Karen H. Vousden, Andrew C. Phillips
openaire +3 more sources
The BRCA2 is a histone acetyltransferase [PDF]
Oncogene, 1998 Patients carrying mutations in BRCA1 or BRCA2 tumor suppressor genes have shown to have high risk in developing breast and ovarian cancers. Two potential functions of BRCA2 were proposed which includes role in the regulation of transcription and also in DNA repair.
J.-P. Zou +3 more
openaire +2 more sources
Acetylation of Lactate Dehydrogenase Negatively Regulates the Acidogenicity of Streptococcus mutans
mBio, 2022 Lysine acetylation, a ubiquitous and dynamic regulatory posttranslational modification (PTM), affects hundreds of proteins across all domains of life.
Qizhao Ma +10 more
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The Acetyltransferase p300/CBP-Associated Factor Is a p53 Target Gene in Breast Tumor Cells
Neoplasia: An International Journal for Oncology Research, 2004 p300/CBP-associated factor (PCAF) is a coactivator of the tumor suppressor, p53. PCAF participates in p53's transactivation of target genes through acetylation of both bound p53 and histones within p53 target promoters.
George S. Watts +6 more
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Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2019 The aim of the study. To determine the ffect of polymorphism of glutathione-S-transferase class M1 and NAT2 genes on the efficacy of tuberculosis treatment. Material and methods.
Todoriko L. D. +2 more
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The Role of Histone Protein Acetylation in Regulating Endothelial Function
Frontiers in Cell and Developmental Biology, 2021 Endothelial cell (EC), consisting of the innermost cellular layer of all types of vessels, is not only a barrier composer but also performing multiple functions in physiological processes.
Zhi Fang +5 more
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Distribution of choline acetyltransferase (ChAT) immunoreactivity in the brain of the teleost cyprinus carpio [PDF]
, 2018 Cholinergic systems play a role in basic cerebral functions and its dysfunction is associated with deficit in neurodegenerative disease. Mechanisms involved in human brain diseases, are often approached by using fish models, especially cyprinids, given ...
Casini, Arianna +3 more
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Gcn5-Related N-Acetyltransferases (GNATs) With a Catalytic Serine Residue Can Play Ping-Pong Too
Frontiers in Molecular Biosciences, 2021 Enzymes in the Gcn5-related N-acetyltransferase (GNAT) superfamily are widespread and critically involved in multiple cellular processes ranging from antibiotic resistance to histone modification.
Jackson T. Baumgartner +13 more
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