Results 191 to 200 of about 218,218 (394)
The PP2A‐B56 Binding Site LxxIxE Contributes to Asp‐Mediated Spindle Pole Stability
Cytoskeleton, EarlyView.ABSTRACT The organization of microtubules into a mitotic spindle is critical for animal cell proliferation and involves the cooperation of hundreds of proteins whose molecular roles and regulation are not fully understood. The protein product of the Drosophila gene abnormal spindle, Asp, is a microtubule‐associated protein required for correct mitotic ...
Margaux Quiniou +6 more
wiley +1 more source
An Orthogonal Way of Writing the Tubulin Code
Cytoskeleton, EarlyView.ABSTRACT The Elongator complex has long been characterized for its role in tRNA modification and modulation of protein translation. Beyond these established functions, recent findings reveal an unexpected role for Elongator in directly interacting and tuning microtubule dynamics and properties, broadening its biological significance in eukaryotic cells.
Vicente Jose Planelles‐Herrero +1 more
wiley +1 more source
A sensitive fluorescent assay for N-acetyltransferase activity in human lymphocytes from newborns and adults [PDF]
, 1979 Miriam H. Meisler, C.Michael Reinke
openalex +1 more source
Clinical Pharmacology in Drug Development, EarlyView.Abstract A modified controlled‐release sodium valproate formulation (VAL001, test) was compared with an approved enteric‐coated tablet formulation (Absenor, reference). Pharmacokinetics and safety/tolerability were evaluated in healthy subjects to bridge with positive efficacy results from an early‐phase patient trial of valproate in combination with ...
Nikhil Ahuja +8 more
wiley +1 more source
Carnitine Acetyltransferase in Nervous Tissue
, 1966 Richard E. McCaman +2 more
openalex +1 more source
Multiple N-acetyltransferases and drug metabolism. Tissue distribution, characterization and significance of mammalian N-acetyltransferase [PDF]
, 1973 D. J. Hearse, Wendell W. Weber
openalex +1 more source
ESC Heart Failure, EarlyView.Abstract Introduction Cardiac energy metabolism is disrupted in heart failure with preserved ejection fraction (HFpEF), as characterized by a switch from glucose oxidation towards fatty acid oxidation. However, although oxidation of ketones is an important source of ATP it remains unclear how the heart oxidizes ketones in HFpEF.
Qiuyu Sun +8 more
wiley +1 more source
The kinetic properties of human placental choline acetyltransferase [PDF]
, 1971 David L. Morris +2 more
openalex +1 more source
European Journal of Heart Failure, EarlyView.Abstract Obesity and heart failure (HF) represent two growing pandemics. In the general population, obesity affects one in eight adults and is linked with an increased risk for HF. Obesity is even more common in patients with HF, where it complicates the diagnosis of HF and is linked with worse symptoms and impaired exercise capacity. Over the past few
Gianluigi Savarese +28 more
wiley +1 more source